Ajay Thatte

UT Austin ‘21 to Ph.D. Student at UPenn • @MJMitchell_Lab @NSF Graduate Research Fellow • Lipid Nanoparticles for Immune Engineering • BlueSky: ASThatte

[Ajay Thatte @ASThatte2]

Super excited to share a major part of my dissertation work, now out in Advanced Materials!

[Mike Mitchell @MJMitchell_Lab]

Check out our latest in Advanced Materials led by recent @MJMitchell_Lab PhD @ASThatte2 in collaboration w @JilianMelamed @WeissmanLab on a steroid LNP platform for mRNA delivery while mitigating inflammation for treating autoimmune disease!

Open access: https://t.co/VoevrGC2mN

[Mike Mitchell @MJMitchell_Lab]

Excited to announce that @MJMitchell_Lab PhD student @ASThatte2's thesis defense titled “Engineering mRNA lipid nanoparticles to combat inflammatory and autoimmune disease” is tomorrow, June 5th at 2 PM ET!

Location: Glandt Forum, @UPennSinghNano

Zoom: https://t.co/JA2fwImkep

[Alex Hamilton @a_hmltn]

Thrilled to share the final installment from my Ph.D. research @MJMitchell_Lab! Featuring high-throughput screening using molecular barcoding, a cancer vaccine model, and new tools to evaluate LNP protein corona formation!

Read it in Advanced Materials: https://t.co/Qji4plz4ng

[Ajay Thatte @ASThatte2]

Had so much fun writing this Focus Article on next-gen CAR T cell engineering using lipid nanoparticles!

[Mike Mitchell @MJMitchell_Lab]

Check out our latest in Nanoscale Horizons co-led by @MJMitchell_Lab Postdocs and PhD students Melgious Ang, Ann Metzloff, and @ASThatte2 on lipid nanoparticles for engineering next generation CAR T cell immunotherapy!
https://t.co/6LKSYH66k3

[Ajay Thatte @ASThatte2]

@rvdmnanomeds @WillemNANO @radboudumc Congrats, Roy!

[Ajay Thatte @ASThatte2]

@nanoMEZmerize @MJMitchell_Lab @WeissmanLab @JilianMelamed Thanks, Marco!

[Ajay Thatte @ASThatte2]

Thank you to #CRS2025 for the award! Huge thanks to @MJMitchell_Lab for all the support and @WeissmanLab @JilianMelamed for being the best collaborators!

[Mike Mitchell @MJMitchell_Lab]

Huge congrats to @MJMitchell_Lab PhD student @ASThatte2 for winning the @Merck best poster award at #CRS2025 for his work on mRNA LNP autoimmune therapies! @CRSScience

[Ajay Thatte @ASThatte2]

@SwingleKelsey @MJMitchell_Lab @WeissmanLab @JilianMelamed Thanks, Kelsey!

[Mike Mitchell @MJMitchell_Lab]

We will also have two posters by @ASThatte2 on steroid lipid nanoparticles for mRNA autoimmune disease therapeutics and Melgious Ang on photoactivatable lipid nanoparticles! #CRS2025 @CRSScience

[Mike Mitchell @MJMitchell_Lab]

Mitchell Lab is off to #CRS2025 to give 8 talks by @Junchao_online @_emilyhan_ @DongyoonKim5 @HannahGeisler_ @ShiQiangqiang @hannahyamagata @hannahsafford_ on mRNA vaccines, lipid nanoparticles, cancer immunotherapy, fetal and maternal health, CNS targeting and more! @CRSScience

[Ajay Thatte @ASThatte2]

@MJMitchell_Lab @MagBillingsley @BWFUND Wooo go Maggie!

[The New York Times @nytimes]

Breaking News: A baby with a rare disorder made medical history by receiving the first custom gene-editing treatment. The technique used has the potential to help people with thousands of other uncommon genetic diseases. https://t.co/6RB5ttiKmX

[Mike Mitchell @MJMitchell_Lab]

Check out our latest publication in @nanoletters led by @MJMitchell_Lab PhD student and lab softball Coach @hannahsafford_ where we explore tuning LNP elasticity using atomic force microscopy to enhance mRNA LNP delivery to the placenta!

Link to article: https://t.co/lKsE9Ua2IF

[Ajay Thatte @ASThatte2]

Congrats to star undergrad, Ben Nachod for winning the William C. Hall Scholarship! Great job! 🎉@MJMitchell_Lab @PennEngineers @pennbioeng

[SFBiomaterials @SFBiomaterials]

We are thrilled to announce the Society's 2025 Award Recipients and celebrate their remarkable achievements in the field of biomaterials science. Join us in applauding the exceptional leaders who are shaping the future of biomaterials! Read more here - https://t.co/0rSGLmyjB4

[Mike Mitchell @MJMitchell_Lab]

Standing room only for @SwingleKelsey’s seminar on mRNA LNPs to treat pregnancy disorders at @Penn’s Center for Women’s Health hosted by @Marisa_S_B! What a special opportunity to see one of our own from @MJMitchell_Lab give their faculty interview seminar on campus! #proudPI

[Aoife O'Farrell @O_Farrell_Aoife]

Very excited to share our new work, now on @biorxivpreprint, on specificity of memory in human macrophages https://t.co/gQvcAlCs12 (1/8)

[Ajay Thatte @ASThatte2]

@SwingleKelsey @Nature @pennbioeng @MJMitchell_Lab Congratulations, Kelsey!

[Kelsey Swingle @SwingleKelsey]

Thrilled to share our recent work out today in @Nature on an mRNA therapeutic to treat pre-eclampsia! This work has been a true passion project from my time @pennbioeng in @MJMitchell_Lab, and I’m excited to continue important research in women’s health!

https://t.co/xntZAZsPoN

[Mike Mitchell @MJMitchell_Lab]

Come check out a killer poster by @hannahyamagata on a new class of aromatic lipid nanoparticles that outperform industry standard mRNA vaccines this morning at 10am at #BMES2024! We also have two posters by @MJMitchell_Lab undergrads Ben Nachod and Sridatta Teerdhala!

[Ajay Thatte @ASThatte2]

Enjoyed highlighting this comprehensive study in @NatChemEng linking biophysical cues to mechanisms of gene delivery!

[Mike Mitchell @MJMitchell_Lab]

Check out our latest in Nature Chemical Engineering @NatChemEng led by @MJMitchell_Lab PhD student @ASThatte2 and Postdoc @DongyoonKim5 on Hai-Quan Mao's work identifying fluid viscosity as a key biophysical parameter governing gene delivery!

Free access: https://t.co/THNpBK6KpD