O Atlético de Madrid é o clube das 5 principais ligas com mais jogos sem sofrer gols desde a chegada de Diego Simeone.
Atlético de Madrid: 257 🆙
Juventus: 247
Manchester City: 231
Barcelona: 230
PSG: 229
🔴⚪
El Atlético de Madrid, con Diego Pablo Simeone como entrenador, continúa sin perder un sólo partido de eliminatoria de Champions como local:
13/14:
4-1 vs Milán.
1-0 vs Barcelona.
0-0 vs Chelsea.
14/15:
1-0 vs Leverkusen.
0-0 vs Madrid.
15/16:
0-0 vs PSV.
2-0 vs Barça.
1-0 vs Bayern.
16/17:
0-0 vs Leverkusen.
1-0 vs Leicester.
2-1 vs Madrid.
18/19:
2-0 vs Juventus.
19/20:
1-0 vs Liverpool.
21/22:
1-1 vs Manchester United.
0-0 vs Manchester City.
23/24:
2-1 vs Inter.
2-1 vs Dortmund.
24/25:
1-0 vs Madrid.
25/26:
4-1 vs Brujas.
13 victorias, 6 empates, 0 derrotas.
25 goles a favor, 6 goles en contra.
QUÉ LOCURA DE DATOS.
Los dos mejores fichajes esta temporada del Atleti están claros.
Pubill y Hancko.
Vaya solidez, vaya salida de balón, son dos muros.
Por fin tenemos una pareja de centrales top, cosa que no pasaba desde el Godin-Miranda.
ESTAMOS MUY DE VUELTA
🚨 Gregory Van der Wiel's incredible testimony about his career 😳🥺
𝗔𝗕𝗦𝗢𝗟𝗨𝗧𝗘𝗟𝗬 read this 👇
“I won 16 trophies. And I felt nothing. No joy, no pride, no relief. Nothing. I couldn’t enjoy a single moment of my career. Because I was too busy… wearing a mask. Pretending to be okay. Avoiding anything that might unsettle me. Showing that I had everything under control.
I wore that mask for so long that I eventually became the mask itself. A robot playing a role without feeling a thing.
If you feel this way, that mask isn’t protecting you. It’s killing you. Take it off.
What would you give to play without fear? To step onto the field and feel totally FREE. No pre-game anxiety. No post-game depression. Just you. Fully present. Fully focused. Fully yourself.
Most athletes will never know that feeling. They’ll spend their entire careers playing in fear. Fear of the coach’s reaction. Fear of the fans’ judgment. Fear of the media headlines. Fear of their own thoughts.
And they’ll call it ‘pressure.’ They’ll say: ‘That’s just football.’
It’s not. It’s a prison. And I lived in it for 15 years.
I played stiffly when I should have played freely. I held back when I should have exploded. I doubted myself when I should have had confidence.
The version of myself I could have been? It still exists, somewhere. It never saw the light of day. It still torments me, it still haunts me.
But you? You still have time.
You have time to develop the mindset that will set you free. You have time to perfect the tools that will make you invincible in every match.
This inner work is demanding. It’s the hardest thing you’ll ever do in your life. And it’s truly the only thing that changes everything.”
En las cuentas de la Comunidad de Madrid una de las cosas más vergonzosas son los intereses de demora a Quirón y Ribera. En 2025 fueron 26 millones
En el hilo adjunto te lo explicaba
Lo digo por contextualizar lo de la inversión para investigar el cáncer vs Broncano
Un mercado más y seguimos sin tener un 5 de garantías. Nos han traído un mejicano que es una incógnita y Rodrigo, que posiblemente será un grande, pero aún le queda. Nos han dejado a medias una vez más.
1⃣ Parece una calle cualquiera, pero el número 35 del Carrer de l'Avenir de Barcelona —concretamente la 2ª puerta de la planta 6ª— es el domicilio más mencionado en el Boletín Oficial del Registro Mercantil (BORME) durante los últimos 20 años. Sale en 2.196 ocasiones.
¿Por qué?
El Cholo podrá cometer errores, por supuesto. Pero el dia que veáis en la cara de Gil Marín, Alemany o Cerezo la mitad del sufrimiento que tiene en cada partido viendo al equipo, empezamos a hablar de quien es el problema. Se llama sentimiento
This isn’t a random scientist who got lucky.
Mariano Barbacid discovered the first human oncogene in 1982. He isolated H-RAS from bladder cancer cells and proved a single point mutation could trigger cancer. That finding launched the entire field of molecular oncology.
KRAS mutations cause 90% of pancreatic cancers. For 43 years, oncologists called KRAS “undruggable” because the protein had no obvious binding pocket. Barbacid spent the last decade using genetically engineered mice to systematically test every node in the KRAS signaling pathway, looking for combinations that would work without killing the patient.
The triple therapy blocks KRAS three ways at once: the main growth signal, the escape routes through EGFR and HER2, and the stress-response backup through STAT3. Cut the engine, seal the exits, disable the emergency system. Tumors vanished in mice and didn’t return for 200+ days after treatment stopped.
Pancreatic cancer has a 13% five-year survival rate. 8% for the ductal adenocarcinoma type this therapy targets. Most patients live one year after diagnosis.
The catch: this is preclinical. Human trials are 3+ years away. One of the drugs, RMC-6236, might get approved this year, but the full triple combination has regulatory hurdles.
Still. The man who discovered human oncogenes in 1982 may have just figured out how to eliminate the cancer those genes cause. That’s a 43-year arc from first principles to potential cure. Science rarely works this clean.