The ATLANTIS IBS Trial

In a trial of 463 primary care patients in England, amitriptyline was shown to be superior to placebo in key IBS therapeutic measures. Sharing the good news!

[The ATLANTIS IBS Trial @atlantisIBS]

What about side effects? The ATLANTIS trial showed low-dose amitriptyline was well-tolerated. While some anticholinergic effects were noted (e.g., dry mouth), they were generally mild and manageable via patient self-titration. Favourable risk/benefit profile.

[The ATLANTIS IBS Trial @atlantisIBS]

The ATLANTIS trial confirms low-dose amitriptyline's role in managing IBS. At low doses, its primary effect is on visceral hypersensitivity, not mood, offering a neurological approach for refractory symptoms. Visit https://t.co/QLfb98ocRv

[The ATLANTIS IBS Trial @atlantisIBS]

IBS is more than your gut - it's your quality of life. The ATLANTIS trial showed low-dose amitriptyline can help you get back to living with fewer interruptions from pain & discomfort. Talk to your doctor or visit https://t.co/rW9CqTw31F for more

[The ATLANTIS IBS Trial @atlantisIBS]

IBS symptoms can change daily. The ATLANTIS trial showed patients could gradually adjust their own amitriptyline dose, giving them more control. Flexible treatment that adapts to you. Visit https://t.co/rW9CqTw31F for more info.

[The ATLANTIS IBS Trial @atlantisIBS]

Low-dose amitriptyline shows clear superiority over placebo for IBS (61.3% vs 45.1% reported significant improvement). Funded by the NHS, the ATLANTIS trial provides robust evidence for this second-line treatment. See the data for yourself: https://t.co/QLfb98ocRv

[The ATLANTIS IBS Trial @atlantisIBS]

Struggling with IBS patients who fail to respond to first-line therapies? Don't forget low-dose amitriptyline. The ATLANTIS trial (n=463) provides compelling RCT evidence for this effective, safe, and inexpensive second-line option. Read the paper: https://t.co/QLfb98ocRv

[The ATLANTIS IBS Trial @atlantisIBS]

Looking to improve outcomes for refractory IBS without increasing consultation time? The ATLANTIS trial protocol empowers patients with self-titration of low-dose amitriptyline, a NICE-recommended therapy. See https://t.co/QLfb98ocRv for details

[The ATLANTIS IBS Trial @atlantisIBS]

Struggling with IBS patients who fail to respond to first-line therapies? Don't forget the evidence for low-dose amitriptyline. The ATLANTIS trial (n=463) provides compelling RCT evidence for this effective, safe, and inexpensive second-line option. Read the paper: https://t.co/SqXL9KxAVq

[The ATLANTIS IBS Trial @atlantisIBS]

Looking to improve outcomes for refractory IBS without increasing consultation time? The ATLANTIS trial protocol empowers patients with self-titration of low-dose amitriptyline, a NICE-recommended therapy. See https://t.co/QLfb98oKH3 for details

[The ATLANTIS IBS Trial @atlantisIBS]

IBS symptoms can change daily. The ATLANTIS trial showed patients could gradually adjust their own amitriptyline dose, giving them more control. Flexible treatment that adapts to you. Visit https://t.co/rW9CqTw31F for more info.

[The ATLANTIS IBS Trial @atlantisIBS]

Tried everything for your IBS? The ATLANTIS trial found low-dose amitriptyline could help when other treatments don't. A new, evidence-based option for persistent symptoms. Ask your GP or visit the trial's website: https://t.co/rW9CqTw31F

[The ATLANTIS IBS Trial @atlantisIBS]

📈 When first-line treatments prove ineffective, bring your IBS patients relief with amitriptyline. The robust ATLANTIS trial (n=463) demonstrates significant improvements in pain, bloating, and quality of life compared to placebo. See the trial's website for more: https://t.co/ZJqGu8L2TH

[The ATLANTIS IBS Trial @atlantisIBS]

🔑 Looking for effective next steps after first-line IBS therapies fall short? The ATLANTIS trial provides compelling evidence for amitriptyline as your second-line approach. This underutilised option significantly improves bowel habit satisfaction and reduces symptom impact on daily functioning. A NICE-compliant, evidence-based solution that could make a real difference for your IBS patients: https://t.co/ZJqGu8L2TH

[The ATLANTIS IBS Trial @atlantisIBS]

⚕️ The ATLANTIS treatment protocol allows patient self-titration of low-dose amitriptyline, reducing consultation burden while improving outcomes. Well-tolerated with manageable side effects, it empowers patients and delivers results. Read the Lancet paper for more: [link]

[The ATLANTIS IBS Trial @atlantisIBS]

📊 Want better outcomes for your IBS patients? The ATLANTIS trial points in a possible direction: Significant reductions in symptom severity scores across 55 general practices in a rigorous RCT. Amitriptyline is a NICE-compliant, effective, easy-to-manage treatment option.

[The ATLANTIS IBS Trial @atlantisIBS]

Tried everything for your IBS? The ATLANTIS trial found low-dose amitriptyline could help when other treatments don't. A new, evidence-based option for persistent symptoms. Ask your GP or visit the trial's website: https://t.co/rW9CqTw31F

@nihrresearch
@ukgastrodr
@gutscharityuk

[The ATLANTIS IBS Trial @atlantisIBS]

What about side effects? The ATLANTIS trial showed low-dose amitriptyline was well-tolerated. While some anticholinergic effects were noted (e.g., dry mouth), they were generally mild and manageable via patient self-titration. Favourable risk/benefit profile. See https://t.co/SqXL9KxAVq for full details.

@nihrresearch
@ukgastrodr
@gutscharityuk

[The ATLANTIS IBS Trial @atlantisIBS]

IBS is more than your gut - it's your quality of life. The ATLANTIS trial showed low-dose amitriptyline can help you get back to living with fewer interruptions from pain & discomfort. Talk to your doctor or visit https://t.co/9HqjErWbzn for more

@nihrresearch
@ukgastrodr
@gutscharityuk

[The ATLANTIS IBS Trial @atlantisIBS]

The ATLANTIS trial confirms low-dose amitriptyline's role in managing IBS. At low doses, its primary effect is on visceral hypersensitivity, not mood, offering a neurological approach for refractory symptoms. Visit https://t.co/QLfb98ocRv

@nihrresearch
@ukgastrodr
@gutscharityuk

[The ATLANTIS IBS Trial @atlantisIBS]

Looking for a trusted IBS treatment? The ATLANTIS trial was a major NIHR-funded study with 460+ people. Over 60% on low-dose amitriptyline saw significant improvement. Backed by science. See https://t.co/rW9CqTw31F for more info

@nihrresearch
@ukgastrodr
@gutscharityuk