Zima

hi.

[Zima @AtRyan_]

@spicybwoyuk @thisisyourparty @DemSocialists @nycDSA creative

[Zima @AtRyan_]

@shauseth Alphafold has been pretty massive in bio research

[Zima @AtRyan_]

@QueMsVici @ericweinstein Thank you for this

[Taj Ali @Taj_Ali1]

Huge swing away from Labour in Ilford as an Independent councillor is elected.

This was the result in Ilford North at the last General Election

[Edward Snowden @Snowden]

Everyone in the world needs to see this.

Note that this footage permits no room for "it was a mistake," showing repeated, specifically-targeted strikes on the unarmed and even wounded. The sort of behavior the ICJ explicitly forbid in the genocide ruling against Israel.

[Andrew Côté @Andercot]

Groundbreaking New Theory of Life, the Universe, and Everything

@leecronin has a new theory of Selection that draws from information theory, complexity science, physics, chemistry, and biology.

Here's how Assembly Theory provides a universal radar for all possible life:

tl;dr:
- Any possible Object can be described by their complexity, or steps it took to create them, and number, or relative abundance.
- Selection processes produce Objects of high complexity and in large numbers
- This lets you compare how 'evolved' any two things are, whether they are living or not, and makes testable predictions on their evolutionary history.

Just like Entropy quantifies how much information content a system has, Assembly Theory quantifies how 'evolved' any system is.

What does Assembly Theory Answer?
Assembly Theory tries to get at something profound - is there a universal framework for understanding any possible selection process, beyond just what we think of as living systems?

Even further than that, is there a way to understand not just that functions of biological systems (or social systems, etc) are generated via evolution and selection, but how certain forms come to predominate in a given environment - how does evolution select from among a vast possible space of future configurations?

Physics doesn't provide the answer - it makes no difference between random fluctuations, and long processes of selection. Biological natural selection also doesn't explain the origins of life - you have to have an existing complicated chemical landscape to provide Life's building blocks.

And more-so, Biology only heuristically provides a description of how social systems, manufactured products, ideas, and non-living systems can evolve and undergo selection over time.

Assembly Theory is incredible simple and elegant:

Every object has two two key properties:

Assembly Index, or the number of steps it takes to create something. For a molecule this could be number of chemical bonds; for a genetic sequence, the number of DNA letters.

Copy Number, or the relative abundance of of that object in its environment.

With these two concepts we can define Assembly Number, which is roughly, what is the likelihood this object was produced by a selection process, as opposed to random chance?

This is an absolute first for a theory general enough to span chemistry to biology to manufactured products.

In general, it was found that living systems possess an Assembly Number greater than 15, while non-living objects are found to be less.

You can calculate the assembly number of anything using just a mass spectrometer, which is incredible, since @leecronin then used this assembly number to correctly reconstruct a tree of life of evolved systems without any gene sequencing.

Whats the 'So-What' of Assembly Theory?

A mathematically predictive model of natural selection and inheritance, and a generalized threshold of complexity for any system enables something truly profound:

Assembly Theory provides a universal and general 'radar' for any possible living system, or, something that has evolved through natural selection, regardless of its chemical basis - carbon, sulfur, silicon, etc.

Life in our universe may be far stranger than we possibly imagined; Assembly Theory may prove to be the beginnings of an entirely new scientific field - the equivalent of a Statistical Mechanics for any arbitrary evolutionary process.

This is certainly one of the more interesting and novel theories to be published in recent years for its potentially grand-sweeping scope and interdisciplinary nature.

You know it has potential when scientists from physics, chemistry, biology, and complexity theory are all upset and digging in.

@leecronin is one to watch for anyone interested in new foundational theories of Life, the Universe, and Everything.

[Ghost Maggie Serota @maggieserota]

The "He's Just Some Guy" sign is cracking me up

[Nosheen Iqbal @NosheenIqbal]

🎧What will a childless city look like?

I speak to the always great @chakrabortty about how London is flipping itself inside out and why the dystopian hollowing out of the capital impacts the rest of the UK … https://t.co/ZfS8I915Du

[Massimo @Rainmaker1973]

The jackdaws are gathering material for a comfy nest and offering a free trim to the moulting red deer: a kind of symbiotic relationship

[read more: https://t.co/1QJ4vkS1Ad]
[��� HD, Lawrence Chatton: https://t.co/zKMQuCEQlR]
https://t.co/lXWUwHkJXZ

[Bojan Tunguz @tunguz]

10 things money can’t buy:

- Time
- Happiness
- $SVB
- Integrity
- Love
- Character
- Manners
- Health
- Respect
- Morals

[Zima @AtRyan_]

@weird_lil_cornr @eade_bengard @simps_ai Wondering about this too, should devalue content on OF considerably

[Zima @AtRyan_]

@ErrorRaffyline0 @rubinovitz @OpenAI @Penn Could be exciting to see more manual work like labour decreasing in cost as more peons head into industries like construction

[Zima @AtRyan_]

@_bojanin @10x_er Housing as a service (HaaS)?

[pika capital @pikacap]

shoutout landlords

[Ava @noampomsky]

can’t explain why but having one or two little projects you’re very absorbed by is critical for your general wellbeing

[Bojan Tunguz @tunguz]

You can beat a dead horse to water, but rising tides lifts all boats.

[Greta Thunberg @GretaThunberg]

yes, please do enlighten me. email me at [email protected]

[Bojan Tunguz @tunguz]

Thanks to ChatGPT every character can now be playable. You have no excuse for remaining an NPC. Do better.

[Adam Singer @AdamSinger]

@luke_metro Men will ask questions to gptChat instead of going to therapy