Baric Laboratory

Researching #SARSCoV2, SARS-CoV, MERS-CoV, Dengue, Zika, and human norovirus at the University of North Carolina. Shared laboratory account.

[Baric Laboratory @Baric_Lab]

Lots of exciting discussions about antiviral discovery and pandemic preparedness at the READDI symposium last week! @GillingsGlobal @UNC @UNC_Micro_Imm #lovevirology
https://t.co/GaU94OkF0p

[Baric Laboratory @Baric_Lab]

Great showing from past and present UNC coronavirologists at #NIDO2023!

[Baric Laboratory @Baric_Lab]

Our collaborative universal vaccine study is out in @NatureComms. These ferritin nanoparticle RBD vaccines protect monkeys against #SARS2 #Beta #Delta and protect mice against #SARSCoV and bat CoVs. Led by @David_RMartinez and @aschaefe29 from our group.

https://t.co/Lyh1P9UQNt

[Baric Laboratory @Baric_Lab]

Our Post-Acute Sequelae of SARS-CoV-2 (PASC) mouse pathogenesis model paper is out @ScienceTM . This study was led by @KDinnon @SarahRLeist Ethan Fritch and our #lunginstitute collaborators! Also with support from @aschaefe29 and @LisaGralinski
#COVID19

https://t.co/iqsEyk7vdK

[Baric Laboratory @Baric_Lab]

Our #sarbecovirus pathogenesis paper is now out in @mbiojournal . This herculean effort was led by @aschaefe29 @MTFerris with strong support from @SarahRLeist @LisaGralinski @David_RMartinez and our friends from the @Heise_Lab and @msdiamondlab !

https://t.co/Pg5pBwJVXJ

[Baric Laboratory @Baric_Lab]

Our study with @scrippsresearch led by @andrabi_raiees and Dennis Burton is finally out in Nature Immunology. Here we define the protective efficacy of RBD mAbs against SARS-related viruses.

Congrats to @LPVictorTse @David_RMartinez @aschaefe29 and @LisaGralinski !

@NatImmunol

[Baric Laboratory @Baric_Lab]

We're hiring!

We are seeking an experienced virologist to help lead our flavivirus research program. Apply below to join our group at UNC!

https://t.co/wbYFiM7d9D

[Timothy Sheahan @timothysheahan]

Fun! #postdocs on #coronavirus #pathogenesis and #antivirals apply here https://t.co/usDHjsGfM0

[Timothy Sheahan @timothysheahan]

We are looking for #postdocs to study #RNAvirus pathogenesis and therapeutic development #academia #jobs #SARSCoV2 #COVID19 @UNCpublichealth

[Baric Laboratory @Baric_Lab]

#antivirals #postdoc #job posting https://t.co/JZbphIFlZG

[Baric Laboratory @Baric_Lab]

We are looking for Postdocs to study RNA viral pathogenesis, vaccines and therapeutics @UNCpublichealth #jobs #postdocjobs #coronavirus #SARSCoV2 #COVID19 https://t.co/vuU9ojwgza

[Baric Laboratory @Baric_Lab]

#Vaccines #postdoc #job posting https://t.co/vuU9ojwgza

[Timothy Sheahan @timothysheahan]

Psyched to share our story about an oral broadly acting #antiviral therapeutic that diminishes #SARSCoV2 disease and works against #MERSCoV too. Heavy lift by @aschaefe29 @David_RMartinez @Baric_Lab @UNCpublichealth @UNCResearch @ScienceTM https://t.co/Yz1MPqRZpf

[Baric Laboratory @Baric_Lab]

We need more oral #antivirals to treat #COVID19. Here we show nucleoside prodrug therapy can improve #SARSCoV2 disease in mice. @David_RMartinez @aschaefe29 @timothysheahan @UNCResearch @UNCpublichealth @ScienceTM https://t.co/kdswPEFoWj

[Baric Laboratory @Baric_Lab]

This work was led by @KDinnon, @SarahRLeist, Kenichi Okuda, Hong Dang and @FritchEthan and it represents an immense amount of work by many, many people in the lab. It would not have been possible without fantastic collaborators in Pathology and at the Marsico Lung Institute.

[Baric Laboratory @Baric_Lab]

We are excited to share our latest work on SARS-CoV-2 pathophysiology - A model of persistent post SARS-CoV-2 induced lung disease for target identification and testing of therapeutic strategies. https://t.co/OMVLdk3khE

[Baric Laboratory @Baric_Lab]

This manuscript also marks our first use of GeoMx digital spacial profiling, an incredibly useful tool for dissecting the the chronic lung pathophysiology we see after infection.

[Baric Laboratory @Baric_Lab]

NC Science, Math, and Engineering Professionals and Trainees: if you are interested in an opportunity that will help engage K12 students in STEM research, please consider volunteering for the NC Science and Engineering Fair Scientific Review Committee: https://t.co/IL0p5kAQj3

[Baric Laboratory @Baric_Lab]

Our preprint with the @lab_haynes and @Dapeng_LI is out. @David_RMartinez and @aschaefe29 led this from our group and tested the breadth of a #universal #SARSCoV2 vaccine that protected macaques and mice against all tested variants and SARS-like viruses.

https://t.co/bbC2k8kFDy