Happy to see our new protocol published in @bioprotocolbyte I encourage you to read it and explore
a new ex vivo approach to assess mitochondrial ROS by flow cytometry in AAV-tagged #astrocytes in Adult Mice.
https://t.co/iPRagfumT9
#ROS#mitochondria#neuroscience@ibfg_es
Here, we found that mitochondrial Ca2+ efflux, mediated by the NCLX, goes well beyond just controlling ion levels
Inhibition of NCLX activity in #astrocytes - one of the most abundant (and important!) cell types in the brain - increases glycolysis & lactate secretion ⚡️
The actual stars of the brain 🌟
I'm happy to share that the accepted version of my PhD's main work was just made available #OpenAccess 🔓 at the Journal of Neurochemistry, granted with #OpenScience 📖 badges (Open Data & Materials)
🧶
https://t.co/2jCCtn6PSq
@ISN_society
Y el Premio Nobel de Química 2020 va finalmente para Emmanuelle Charpentier y Jennifer Doudna por "the development of a method for genome editing". Se premian las #CRISPR pero NO se reconoce la contribución esencial de Francis Mojica.
@NobelPrize
https://t.co/gOQbuCjVbT
PREDOCTORAL CONTRACT ON BRAIN ENERGY METABOLISM AND AUTOPHAGY IN SALAMANCA
Are you interested, or do you know someone interested, in carrying out a 4-yr doctoral thesis on the connection between brain metabolism and autophagy using genetic mouse models?
Please, read/forward 👇
Read the Sept Special Issue @TrendsImmuno on #Microglia & #Astrocytes, showcasing the heterogeneity & complex roles of these non-neuronal cells in #mouse & #human#CNS, the crosstalk between these cells & other #brain cells, & health/disease implications!! https://t.co/l3ik33mL48
A missense in HSF2BP causing Primary Ovarian Insufficiency affects meiotic recombination by its novel interactor C19ORF57/BRME1 https://t.co/B3k8Ayxdza
A Nature study shows that astroglial mitochondrial cannabinoid receptor (CB1) signaling can directly regulate glucose metabolism to fine-tune neuronal activity and social interactions in mice. https://t.co/LZfdvK3eRM
We know that behavioral responses can be modulated by specific a brain region/circuit and/or cell-type. But this study highlights the fact that the interaction between different brain cells might be also very important to understand how the brain control our actions. 12/15
This is why @MarsicanoLab joined forces with @bolanosjuanp, who has extensively demonstrated the ability to decipher specific mechanisms controlling brain bioenergetics and dissecting opposite bioenergetic roles between neurons and astrocytes 4/15
https://t.co/HxGgtnATrc
#IBFG_Paper | @bolanosjuanp´s lab & @MarsicanoLab have published in @nature the article "Glucose metabolism links astroglial mitochondria to cannabinoid effects".
More info: https://t.co/UhmXQa83FC
Group web: https://t.co/vPgcS2cbiV
L’équipe de @MarsicanoLab@Inserm@univbordeaux, en collaboration avec @usal, met en lumière les relations entre la consommation de cannabis et la réduction des interactions sociales des consommateurs. Publication aujourd’hui dans @nature
Illustration par @cp_illustrates
Thrilled to announce our work is out today @Nature! Enjoy this open article on how #cannabinoid(s) rely on #mitochondria(l) CB1R and #ROS in #astrocyte(s) to set social #behavior. A joint tour de force with @MarsicanoLab lab and cols. Thread below! n/10
https://t.co/jcV0FeT6vM
It's finally out! Our collaborative work together with the group of @bolanosjuanp is out in @nature. Our study is the first to show that the social impairment sometimes associated with cannabis use is the result of altered brain glucose metabolism (1/15)
https://t.co/ysTUg0W5Ss
📢El IBFG ofrece #ContratosPuente2020 con el objetivo de financiar el comienzo de la #TesisDoctoral. El plazo de solicitud finaliza el 25/JULIO/2020.
Mas información del procedimiento⬇️