@nihardesai89@ASH_hematology@docakx@AbbasiMuqtadir@drkeithsiau@DrRishabhOnco@drsthanus Management: as long as the diagnosis of PCL is confirmed, I’d like to intensify the treatment in the induction phase with polychemotherapy (e.g. DTPACE), followed by autoBMT.
Given the patient’s age and the presumable frailty, I’d go with quadruple therapy based on daratumumabe.
EDITORIAL | Ninguém vai chorar pelo Irã – “Sejam lá quais as motivações por trás da guerra, se a derrubada do regime iraniano for o seu resultado, será bom para o mundo inteiro”. Leia o texto completo em https://t.co/HirYPStZD9
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ANEMIA IS NOT A LIST OF DIAGNOSES
We’re taught to approach anemia by pattern.
We use mechanisms implicitly.
We rarely articulate them.
Few are taught to layer probability onto physiology.
Critical appraisal of RCTs isn’t rocket science despite what some say.
If the control arm is not the standard of care at the time the study was run (sadly this happens all too frequently) the results are not applicable to your practice.