Birgit Habenstein

PI @CNRS in #NMR of molecular assemblies, amyloids, membrane proteins, lipids

[Birgit Habenstein @bihalo]

Our work on how Geobacillus MreB interacts with ATP, ADP and lipid membranes has today been published by the Biophysical society! Nice result of a productive collaboration! https://t.co/LA00nAkCua

@CNRSchimie

[Birgit Habenstein @bihalo]

In our today published paper in Advanced Science we show how a master-regulator membrane-targeting sequence, initially described in bacteria, confers membrane phase dependant nanodomain association! Great collaboration! @CNRSchimie @CNRSbiologie https://t.co/fTv7ewy56K

[Birgit Habenstein @bihalo]

The 6ème Journée RMN du Grand Sud will be held in Bordeaux on 19th May 2026! We are looking forward to welcoming you with a great program including two invited lectures by Rasmus Linser and Anne Lesage. Registration is free : https://t.co/bWCOW737LS
@CNRS @iecb_bordeaux

[Birgit Habenstein @bihalo]

Our first review of the RePo-SUDOE consortium was published today! We review how efficient computational and experimental biophysics cooperate in cancer drug development.
https://t.co/q1e1bQHz4o

[Birgit Habenstein @bihalo]

You still have time to register early bird for the conference on integrative structural biology in Bordeaux from 15th-19th Dec.! We have delayed the deadline for abstract submission until 7th Oct. ⏲️ @CNRSchimie https://t.co/8yAFLYlAiW

[Birgit Habenstein @bihalo]

I am looking for a motivated biochemistry or biophysics engineer (Master 2 level) for a position at the @CNRSchimie in Bordeaux. Don't hesitate to contact me directly or submit your application at the dedicated website:
https://t.co/jkFcXuOgol

[Birgit Habenstein @bihalo]

It's time to register for the 4th Integrative Structural Biology Meeting from 15th-19th Dec. in Bordeaux... We wait for you with a list of exceptional speakers and will be happy to welcome you! For more information see below:
https://t.co/8yAFLYlAiW @CNRSchimie @CNRSbiologie

[Birgit Habenstein @bihalo]

I am happy and honored to be selected for promotion to research director at @CNRSchimie ! A great thanks goes to all my great colleagues and collaborators!

[RePo-SUDOE @RePoSUDOE]

ES 📣El proyecto RePo-SUDOE estuvo presente en la reunión anual del CBMN, compartiendo avances con estudiantes e investigadores en biofísica y reposicionamiento de fármacos 💊🧪

¡Gracias al CBMN por su apoyo a la ciencia colaborativa!

📎 https://t.co/xh0uSGotKB

[Birgit Habenstein @bihalo]

Are you motivated to join the international and interdisciplinary team @RePoSUDOE @CNRSchimie @CNRSAquitaine ? Only pre-requisite: you need a PhD in chemistry or biophysics. ... you can find the job offer here or dm me: https://t.co/6oZqJjrOA6

[Birgit Habenstein @bihalo]

A great conference in beautiful countryside, thanks to the organizers of our first RePo-SUDOE conference!

[RePo-SUDOE @RePoSUDOE]

FR 🌟 La 1ère Conférence du Projet RePo-SUDOE a réuni des experts internationaux pour discuter de drug repurposing, partager des cas de succès et promouvoir de nouvelles opportunités d’innovation pour la région SUDOE💊🌍.

Plus d'information: https://t.co/RHF7m6hex8

[CNRS Chimie @CNRSchimie]

Pour la huitième année consécutive, le CNRS a renouvelé son soutien en faveur des jeunes chimistes en relançant l’appel à projet Emergence, qui finance des projets novateurs par rapport à l'état de l'art.

Retrouvez ici les lauréats et leurs portraits 📝

https://t.co/6qpTYjb6HB

[Birgit Habenstein @bihalo]

It was a great opportunity to visit two sites of the University of Sao Paulo University, in Sao Paulo and Ribeirao Preto. Thank you @CNRSchimie !

[Jacques Maddaluno @jmaddalu]

Trois témoignages de jeunes collègues sur le programme Emergence@International de @CNRSchimie présentés dans https://t.co/m3R7VlyWli

[Birgit Habenstein @bihalo]

After 3 years of hard work, Dr. Zeren Xu has obtained today the PhD title of the University of Bordeaux. Same day as the publication of his first article! Congratulations !

[Jean-Philip Piquemal @jppiquem]

#compchem New group paper published in @CommsBio:
"Dynamic pre-structuration of lipid nanodomain-segregating remorin proteins"
https://t.co/Fk6cGfLz39
Remorins are multifunctional proteins, regulating immunity, development and symbiosis in plants. When associating to the membrane, remorins sequester specific lipids into functional membrane nanodomains. The multigenic protein family contains six groups, classified upon their protein-domain composition. Membrane targeting of remorins occurs independently from the secretory pathway. Instead, they are directed into different nanodomains depending on their phylogenetic group. All family
members contain a C-terminal membrane anchor and a homo-oligomerization domain, flanked by an intrinsically disordered region of variable length at the N-terminal end. We here combined molecular imaging, NMR spectroscopy, protein structure calculations and advanced molecular dynamics simulation to unveil a stable pre-structuration of coiled-coil dimers as nanodomain-targeting units, containing a tunable fuzzy coat and a bar code-like positive surface charge before membrane association. Our data suggest that remorins fold in the cytosol with the N-terminal disordered region as a structural ensemble around a dimeric anti-parallel coiled-coil core containing a symmetric interface motif reminiscent of a hydrophobic Leucine zipper. The domain geometry, the charge distribution in the coiled-coil remorins and the differences in structures and dynamics between C-terminal lipid anchors of the remorin groups provide a selective platform for phospholipid binding when encountering the membrane surface.
Great work led by @bihalo. @AdrienSchahl @Matth_Chavent

[Birgit Habenstein @bihalo]

Thank you for this nice collaborative work where we show that flotillins can act as the destabilizers of phospholipid membranes! Surprisingly, this effect is not only inflicted by the membrane interacting domains but also by the coiled-coil region. @a_alvarezmena @BramkampLab

[Birgit Habenstein @bihalo]

Thanks for welcoming me at the University of Sao Paulo and thanks for giving me this opportunity (@CNRSchimie)! It was great to discuss science and perspectives. USP campus sites in Sao Paulo and Ribeirao Preto are exceptional places for science, landscape and hospitality.

[Birgit Habenstein @bihalo]

@EmMcRae_Chem @CNRS @iecb_bordeaux Thanks for your enthusiastic participation!

[Emma McRae @EmMcRae_Chem]

Day 1 of the Structural Biophysics Workshop @CNRS @iecb_bordeaux! ✅ Tons of fun learning AFM and Cryo-EM techniques and meeting lots of European colleagues in gorgeous Bordeaux! And lots of practice for my French 😅 Thanks to @bihalo (and others!) for organizing!

[Birgit Habenstein @bihalo]

Thanks to the organizers for this great CCPN meeting and the fantastic walk (even sunny!!)!

[Chris Waudby 🦋 @chris_waudby]

@cerm_cirmmp Final talk of the morning is from Birgit Habenstein @bihalo on solid-state NMR of biological assemblies

[Chris Waudby 🦋 @chris_waudby]

@cerm_cirmmp Final talk of the morning is from Birgit Habenstein @bihalo on solid-state NMR of biological assemblies