BII Interest Group

We are a group of scientists, hoping to share insights of our work. Our hope is that you too enjoy the art of science as much as we do!

[BII Interest Group @BIIInterest]

Scientists from BII, together with scientists from GIS and Duke-NUS Medical School, made an important discovery about the shape and structure of the SARS-CoV-2 virus' genetic material that can help in producing more effective drugs to treat #COVID19.
https://t.co/whEeg9LYAU

[BII Interest Group @BIIInterest]

Dr. Sebastian Maurer-Stroh was recently featured in the Straits Times, where he shared that based on GISAID data, the Delta variant is very successful and no other variant looks set to take the world by storm in the near future. https://t.co/aJLP6nNL2m

#BII #COVID19 #GISAID

[BII Interest Group @BIIInterest]

Leveraging on NSCC’s #supercomputing resources, BII scientists studied #mutation mechanisms of the flu virus by utilizing high performance computing to understand the life cycle of Influenza A Virus to aid in development of #vaccines. | https://t.co/rRPFcGvD92

#virus #Influenza

[BII Interest Group @BIIInterest]

Dr. Sebastian Maurer-Stroh who was featured on The Straits Times yesterday, shared his insights on the #coronavirus #mutations and how it has changed over the past year.

Find out more -> https://t.co/cLZhkIVOO4

#BII #bioinformaticsinstutite #spikeprotein #mutation #COVID19

[BII Interest Group @BIIInterest]

Congratulations to the Computer Vision and Pattern Discovery Group (CVPD)! 🥳🎉

Link to research article -> https://t.co/DizX9kyKmI

Link to CVPD Group page -> https://t.co/nfJecBvETo

#BII #BioinformaticsInstitute #machinelearning

[BII Interest Group @BIIInterest]

BII scientists aided in demonstrating that Y-box-binding protein-1, YB-1, is involved in the last step of cell division and is required to initiate #cytokinesis via live-imaging and confocal microscopy. https://t.co/WcXatcxXFR

#BII #YB1 #phosphorylation

[BII Interest Group @BIIInterest]

BII scientists aided in discovering a previously unknown interaction between SARS-CoV-2 spike protein and #lipopolysaccharide, providing insights to the comorbidities that may increase risk for severe #COVID19 disease and providing new therapeutic targets. https://t.co/s72GpuyaS7

[BII Interest Group @BIIInterest]

Through the use of #moleculardynamics simulations based on homology modelling of a known structure, BII scientists helped predict how changes in the second-shell residues around substrate binding sites influences #affinity in simple #proteinstructures. https://t.co/eAAGJ8mhnk

[A*STAR @ASTARsg]

In the fight against #COVID19, Dr Sebastian Maurer-Stroh and his team at A*STAR are instrumental in setting up and maintaining the genome data shared on GISAID. Find out more : https://t.co/tMRqerO2q1

[BII Interest Group @BIIInterest]

BII scientists sought out to determine if there were differences between #radiomics features derived from patients with nasopharyngeal cancer, recurrent versus non-recurrent regions within the tumor, based on pre-treatment #MRI. https://t.co/qdKL0v6Rgx

[BII Interest Group @BIIInterest]

Scientists from BII's Atomistic Simulations and Design in biology group aided in discovering that targeting an under-studied #mutation of the tumor suppressor, #p53 could lead to new and effective opportunities to treat aggressive #lungcancer. https://t.co/i9aL5tJJ1k

[BII Interest Group @BIIInterest]

APD Lab recently participated in the inaugural Merck Connectivity 2020 challenge on looking at mobile app and device innovation for laboratory research and was awarded the Bronze award for their work.🎉| https://t.co/nTmv3lC5Ok

#BII #apdlab #scientificphoneapps #innovation

[BII Interest Group @BIIInterest]

A collaboration between researchers from BII, Duke-NUS and The University of Texas Medical Branch, have discovered how Dengue virus can change its shape to become resistant to vaccines and therapeutics. | https://t.co/fGCQkOunuU

#BII #bioinformaticsinstitute #dengue #viruses

[A*STAR Research @astar_research]

A*STAR researchers have found that the #dengue virus can change shape 😱

At lower temperatures, the virus' surface looks smooth due to its tightly-bound proteins. At high temperatures, the protein interactions are broken, making the virus look bumpy! | https://t.co/1T4vAeUhKe

[BII Interest Group @BIIInterest]

#BII #BioinformaticsInstitute #NaturalProduct #DrugDevelopment

[BII Interest Group @BIIInterest]

Scientists from BII and SIFBI collaborated to conduct #virtualscreening searching for #sortaseA inhibitors in their in-house natural compound library, identifying the potential of 2 natural compounds, N1287 and N2576, for treating S.aureus infections. | https://t.co/RCnflW15cp

[BII Interest Group @BIIInterest]

Dr. Samuel Gan (PI of the APD Lab) was recently interviewed on Channel NewsAsia 93.8FM on the team's research article with IHPC psychologists on #backgroundmusic for business recovery. | https://t.co/LjGuD2GYyG

Interview(08:40) ->https://t.co/uq4RTzCfVG

#BII #apdlab #psychology

[BII Interest Group @BIIInterest]

Dr. Sebastian Maurer-Stroh and team, were featured on Sunday Times for their contribution to the development of the classification of #SarsCoV2 viral clades and subclades, used to track the virus mutations and movement of the clades around the world. | https://t.co/AuQeqtTdLS

[BII Interest Group @BIIInterest]

A collaboration between researchers from BII, Duke-NUS and The University of Texas Medical Branch, have discovered how #dengue virus can change its shape to become resistant to vaccines and therapeutics. | https://t.co/krZVx3CotB

#BII #bioinformaticsinstitute #viruses

[A*STAR Research @astar_research]

X-men mutants aren’t the only ones that can shape-shift; viruses like #dengue can do it too! ��

A*STAR researchers have found that a strain of #dengue changes its shape from smooth to rough at different temperatures! | https://t.co/1T4vAeUhKe

[BII Interest Group @BIIInterest]

Through the use #DeepLearning techniques, BII scientists aided in the development and validation of an algorithm for the automated calculation of the Investigator's Global Assessment (IGA) scale for standardizing #acneseverity and outcome measures. https://t.co/8adrb1oCg9

[BII Interest Group @BIIInterest]

Scientists from the Multiscale Simulation , Modelling and Design group summarize computational and integrative modelling methods guided by biophysical data that have yielded #molecular insights into the "ins" and "outs" of #enveloped #flavivirus. https://t.co/vxxXTXTvfR