Bing Zhang

Assistant Professor @Westlake_Uni || Stem cell and tissue homeostasis || Systemic regulation of regeneration and health ||

[Cell @CellCellPress]

Now online! Sympathetic-epithelial crosstalk governs tissue-resident memory T cell immunosurveillance in the skin https://t.co/I4UeYVvG37

[Westlake University @Westlake_Uni]

🧬 Our nervous system doesn’t just “feel” stress—it can quietly reshape how tissues defend themselves. In a new @CellCellPress study, Westlake University teams (@bingzhang_lab Lab × Ting Zhou Lab) uncover a neuro-epithelial “translation” circuit.

🔬 Key finding: In an early melanoma mouse model, stress-like sympathetic activation reduced TRM and weakened immune surveillance, while blocking sympathetic signaling helped preserve this frontline defense. This cross-disciplinary work links body-wide stress responses to tissue-level immunity, with implications for cancer immunosurveillance and TRM-driven skin disease.

🔗 Read the full article https://t.co/7ebTjRttCY

#WestlakeUniversity #WhyWestlake #Research #Innovation #WorkAtWestlake #StudyAtWestlake #STEM #Hangzhou #China

[Bing Zhang @bingzhang_lab]

This provides a mechanistic link between stress physiology and tissue immunosurveillance. Congratulations to our co–first authors, Peng Zhang and Juju Miao, and to the entire Zhang & Zhou lab teams at Westlake. Full text link: https://t.co/7K8x5j8oKI

[Bing Zhang @bingzhang_lab]

Delighted to share our recent Cell paper. We identify a neuro–epithelial circuit that serves as a tunable input to barrier immunity: peripheral sympathetic signaling via NE→epithelial ADRB2 (rather than directly to T cells) controls recruitment and establishment of CD8⁺ TRM.

[Bing Zhang @bingzhang_lab]

Thanks Nature for reporting our recent work on intermittent fasting and hair follicle regeneration.

[nature @Nature]

This popular weight-loss regimen stunts hair growth

https://t.co/acph4Mcaor

[Bing Zhang @bingzhang_lab]

Full text link: https://t.co/oVIS3PudV9

[Bing Zhang @bingzhang_lab]

Excited to share our latest article on the impact of intermittent fasting on hair follicle stem cells (HFSCs) and hair follicle regeneration. We found that activated HFSCs undergo apoptosis upon fasting, caused by elevated cellular ROS upon metabolic switching to utilizing fat.

[Cell Press @CellPressNews]

Intermittent fasting has proven benefits for metabolic health, but study shows that it also slows hair growth in mice.

Learn more in @CellCellPress:
https://t.co/6hZlSCGo5u

#WestLakeUniversity Bing Zhang

[Bing Zhang @bingzhang_lab]

The metabolic switching is driven by the increased lipolysis of adipocytes in the niche, which is controlled by signals from the adrenal glands.

[Ezhkova Lab @EzhkovaLab]

🚨Please share: We are looking for a postdoctoral fellow to join our group to study the mechanisms of Merkel cell regeneration and sensory perception. Check out the job announcement👇

[Yejing Ge @yejingge]

Delighted to share our skin transposons paper now online @CellCellPress !#TransposableElements #mobileDNA #Regeneration #Skin #StemCell
https://t.co/J95D8Phtwr

Congrats to outstanding postdoc Ying Lyu and our amazing team YounJoo, Ericka, Richa, @MDA_UTHGrad #proudPI! A big shout out to our incredible collaborators @kchenken , Yue Lu, Taiping Chen, and others @MDAndersonNews .

In our murine model, we saw viral like particles originated from the endogenous retroviruses, accompanied by hair loss and stem cell exhaustion, which can be rescued by antiviral drugs. Very excited about the implications behind these findings, especially how innate antiviral pathways can be leveraged to expose cancer vulnerability #EndCancer. Look forward to the next discoveries!
Full article here: https://t.co/PVtnMJSnkX

[Westlake University @Westlake_Uni]

Join us at the Westlake University's special conference on the biology of aging in Novembe,r in collaboration with Cell Press. The field of aging biology provides essential knowledge into the processes and diseases associated with age. Understanding these cellular and molecular changes is pivotal for the development of strategies aimed at promoting healthier aging and increasing lifespan. Learn more & register here: https://t.co/2LRhZVomcW

[Westlake University @Westlake_Uni]

Applications are now OPEN! Join us this summer for the 'Frontiers of Life Sciences' International Undergraduate Summer Camp 2024 from July 23rd - August 6th.

We are looking for the brightest minds from across the world to learn and experience the latest cutting-edge research techniques and innovations.

Taught by internationally renowned professors, if you are looking to become a future pioneer in life sciences, then our 2-week tuition-free program is not to be missed!

Apply Now:
https://t.co/rT0OyXYBwL

[Jason Buenrostro @JD_Buenrostro]

We are recruiting postdoctoral fellows in neurobiology and development to complement our group specializing in genomic technologies, epigenetics and machine learning. projects are very well funded and we are interested in co-mentorship. Please DM if interested in hearing more!

[Yulia Shwartz @YuliaShwartz]

Are you passionate about unraveling the mysteries of stem cell regulation?

The Shwartz Lab is recruiting talented and driven Postdoctoral Research Associates to embark on an exciting journey to study skin stem cell regulation with us!

[Nature Reviews Molecular Cell Biology @NatRevMCB]

We'll do a more thorough Tweetorial of our February issue next week but for now please enjoy the hairstyles of our cover stars!

They're inspired by our recent Review on "Local and systemic mechanisms that control the hair follicle stem cell niche" by Ting Chen & @bingzhang_lab

[Bing Zhang @bingzhang_lab]

Super excited to share our latest review article on mechanisms of local and systemic regulation of hair follicle stem cells, written together with Dr. Ting Chen! 🌟 https://t.co/t6iozHUy4D

[Nature Reviews Molecular Cell Biology @NatRevMCB]

Now Online Local and systemic mechanisms that control the hair follicle stem cell niche https://t.co/kTJuAEJsbT

[Westlake University @Westlake_Uni]

The 2023 Westlake Postdoctoral Fellowship for Women is part of the Westlake Education Foundation's initiative for Westlake's #womeninSTEM. Through these outstanding individuals, we hope to inspire the general public, especially younger students, and to raise their aspirations in science-related careers.

[HSCRB @HSCRB]

SCRB Professor Ya-Chieh Hsu has received the inaugural Glenn Foundation Discovery Award for her work to understand molecular mechanisms that drive stem cell #aging & identify functionally important genes that can rejuvenate old stem cells in vivo directly https://t.co/6JGPQzTJ9z

[Westlake University @Westlake_Uni]

"I have worked at the three oldest universities in the world, and today I can visit the youngest one in the world. ""Westlake is a university in China, for China, and for the world."– Today Andrew Hamilton, President Emeritus of NYU, addressed our community here at Westlake University #WestlakeGlobal