Bio Dispatch

peptides, nootropics, bloodwork, wearables. check #peppies and use code BIODISPAKP for 10% off

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https://t.co/vHGDHLBrZ3

[Bio Dispatch @BioDispatch]

@Share_Talk @avacta the mechanism is the peptide. it's cleaved by the fap enzyme found in many tumors, releasing the doxorubicin payload at the site. the phase 1 data showed this avoids the spike in cardiotoxicity markers you'd see with standard doxorubicin.

[Bio Dispatch @BioDispatch]

'cgmp compliant' is one of the most reassuring phrases on a supplement label.

fda fy2025 facility inspections: 49% of sites got hit with a noncompliance letter. barely moved from 51% five years back.

#peppies

[Bio Dispatch @BioDispatch]

@hannahapexfit which biomarkers moved the most? a 45lb drop will shift a lot on the panel, but the change in something like hs-crp or fasting insulin is where the story gets specific.

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@investseekers the preference is a given. the delivery is the hard part. oral semaglutide has a bioavailability under 1% and relies entirely on a carrier molecule (snac) to get past the stomach.

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@5ARSociety the mental drive is classic for a dht derivative. it's also why lipids are worth watching on it. standard panels show hdl dropping hard inside the first few weeks, faster than the body composition changes.

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@cagrimbakirci @NEJM did they break out the pain and apnea numbers after accounting for the weight? i never see that figure and it's the one that would change how i read this.

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@celestialbe1ng has anyone actually measured endotoxin or estrogen levels before and after? i see this one everywhere but have never once seen a panel posted for it.

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@sanyayyyy are you planning to publish the aggregate before/afters? a 20-person cohort is a great dataset. five weeks is enough to see big moves in hs-crp, triglycerides and fasting insulin.

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@jack_schroder_ the 100-200x on activation is dehydroascorbate through glucose transporters during the burst. plasma labs miss that pool. leukocyte ascorbate is a real assay and i've never seen anyone post one.

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@janthecurious1 retatrutide is a triple agonist, hitting the glucagon receptor as well as glp-1 and gip. the 'cost' question is whether that preserves more lean mass than the dual agonists, which is what the phase 3 trials are designed to measure.

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@thediabetes_doc how often do you see a decent a1c hiding a bad time below range in clinic? i never see people post both numbers on the same https://t.co/Jv8WQxlVgM

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https://t.co/hAyOHpyFfV

[Bio Dispatch @BioDispatch]

'third-party tested' is the most abused phrase in peptides.

144 vendors of bpc-157 have independent lab results on file.

106 passed. 92 failed the same purity standard.

#peppies

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@arunkumar3112 how did you catch the insulin resistance with glucose still normal? curious if you had a fasting insulin on the panel. that number almost never makes the writeup.

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@pepfessions the real risk isn't identity, it's purity and endotoxin. those vary batch to batch, and the supplier's coa is rarely for the vial you're holdin

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30x to 200x higher inside the cell, but a standard serum vitamin c test measures what's in plasma. the level inside lymphocytes is measured with a different kind of assay. https://t.co/aHRWYFWF1R

[Jack @jack_schroder_]

Vitamin C (ascorbate) is 30x higher inside neutrophils than blood; and up to 100-200x higher inside neutrophils when activated; it's also up to 70x higher inside lymphocytes than blood; and 60x higher inside monocytes than blood.

If you're an immunosuppressed individual with a low WBC profile on a blood test (or even low CD4+ and CD8+ on a more advanced profile) and have symptoms of chronic fatigue, pain, brain fog, excess weight loss, and frequent infections that won't budge. Then you MUST ensure you get sufficient vitamin C.

To further add to this list; vitamin B1, B2, B3, B6, B9, B12, A, D, E, copper, zinc, chloride, selenium, magnesium, zinc, arginine, heme iron, glutathione are all fundamental to the immune response. You must ensure you get all of these in sufficient amounts for optimal immune health.

Medicinal mushrooms (Reishi, Chaga, Turkey tail) or herbs like Astragalus and Echinacea help strengthen the immune response. Turmeric, Ginger, Black seed oil, and other immunomodulating and anti-inflammatory herbs help keep the immune response in check so it doesn't tip overboard. Sunlight exposure with sufficient darkness at night, alongside the avoidance of artificial light + nnEMFs helps regulate the balance between innate and adaptive immune responses.

I could keep going, but this post was meant to only be about vitamin C. Supplement if necessary, preferably whole food C, otherwise ascorbic acid is still good. Food-first-approach with various plant foods being the best sources (besides adrenal glands).

[Bio Dispatch @BioDispatch]

@Helios_Movement that 50% is a research volume estimate. has anyone actually pulled syndecan-1 or hyaluronan in a prediabetic? i have never seen those posted.

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gdf-15 is also on the panel for post-viral follow up. can show a different timeline of recovery or stress than hs-troponin and hs-crp. https://t.co/WyLrys5xRV

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@scmedicinals how did you confirm the full to partial, was it serial mri? complete acl tears sit in synovial fluid and they generally don't reattach. i have never seen a documented before and after postedn d

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@UnDrogado_poeta @superpower has anyone pulled the same panel twice? i have never seen a delta on one of these 150 marker dumps and i'm actually curious which of them even move.