In the New and Notable "Cellular nematics speeding up calcium propagation,"
Aashrith Saraswathibhatla highlights the paper "Nematic cell alignment directs calcium waves in an epithelial monolayer." https://t.co/bLFnMhlcp9
#OPENACCESS: What happens when a cell freezes from the inside? Like a water pipe bursting during winter, intracellular ice can quietly damage stem cells. Raman spectroscopy lets researchers watch this molecular freeze-drama unfold in real time.
https://t.co/RHJI2iX3hv
#OPENACCESS: A robust platform that computes NMR relaxation rates (longitudinal and translation) from MD trajectories, benchmarked on a bunch of proteins. Do you need a magnet for measuring relaxation or not, find out yourself! https://t.co/rUFG99k95z
#OPENACCESS: Quantum tunneling in DNA methylation: A computational study using QM/MM and molecular dynamics. Justin Sato, Annabelle Choi, Peace U. Clement, Gisela Alvarez, To Dang, Daniel Erenso, and Horace T. Crogman. https://t.co/D8oL1gxWos
In the New and Notable "Hypoxia and the limits of nuclear passage," Iden Kurtaliaj highlights the paper "Hypoxia-driven changes in nuclear morphology as a determinant of cell migration." https://t.co/pmtpVlyTrB
New study combining microscopic imaging, AFM, and mass spectrometry reveals hypoxic pancreatic tumors that induce cytoskeletal and nuclear mechanical changes that promote cell invasion, opening new avenues for therapeutic strategies that target mechanics. https://t.co/6IvvkZG8tV
#OPENACCESS: A red-light gate for a cation channel: The conducting state of channelrhodopsin-1 from Chlamydomonas augustae. Istvan Szundi, Vera Muders, Chie Funatogawa, David S. Kliger, Ramona Schlesinger, and Joachim Heberle. https://t.co/VtUS9y5svG
#OPENACCESS: Channel gating in bacteriorhodopsin-like channelrhodopsins with contrasting K+ and Na+ selectivity. Oleg A. Sineshchekov, Elena G. Govorunova, Hai Li, Yumei Wang, and John L. Spudich. https://t.co/Dd3pNZ2aUo
#OPENACCESS: Diverging pH dependence and photocycle dynamics across members of the CryoRhodopsin clade. Sarah Warrelmann, Gerrit H.U. Lamm, Kirill Kovalev, and Josef Wachtveitl. https://t.co/X7sJD5qHnA
Modulation of protein dynamics during a functional cycle of a bateriorhodopsin observed using time-resolved quasielastic neutron scattering experiment provides a first direct observation of protein-dynamics-function correlation. https://t.co/k6R6xOFTzZ
#OPENACCESS: RGS proteins: Potential regulators of mouse melanopsin’s signaling phototransduction cascade across ipRGC subtypes. Lee H. Harkless, K.M. Daly, Grayson P. Ostermeyer, Samer Hattar, R. Lane Brown, and Phyllis R. Robinson. https://t.co/0GJMrGfLPU
#OPENACCESS: Costa et al. combine molecular dynamics simulations, network analysis, and machine learning to study signal transduction in the jumping spider rhodopsin 1, identifying Trp290 and TM6 helix residues as mediators of light-driven GPCR activation. https://t.co/6imQqK1s2W
Antarctic microbes just revealed solar-powered molecular gadgets! Marín et al. discovered novel schizorhodopsins that act like tiny light-driven engines hidden in icy ecosystems. https://t.co/8FlR4Y8wk3