#OPENACCESS: A robust platform that computes NMR relaxation rates (longitudinal and translation) from MD trajectories, benchmarked on a bunch of proteins. Do you need a magnet for measuring relaxation or not, find out yourself! https://t.co/rUFG99k95z
#OPENACCESS: Quantum tunneling in DNA methylation: A computational study using QM/MM and molecular dynamics. Justin Sato, Annabelle Choi, Peace U. Clement, Gisela Alvarez, To Dang, Daniel Erenso, and Horace T. Crogman. https://t.co/D8oL1gxWos
In the New and Notable "Hypoxia and the limits of nuclear passage," Iden Kurtaliaj highlights the paper "Hypoxia-driven changes in nuclear morphology as a determinant of cell migration." https://t.co/pmtpVlyTrB
New study combining microscopic imaging, AFM, and mass spectrometry reveals hypoxic pancreatic tumors that induce cytoskeletal and nuclear mechanical changes that promote cell invasion, opening new avenues for therapeutic strategies that target mechanics. https://t.co/6IvvkZG8tV
#OPENACCESS: A red-light gate for a cation channel: The conducting state of channelrhodopsin-1 from Chlamydomonas augustae. Istvan Szundi, Vera Muders, Chie Funatogawa, David S. Kliger, Ramona Schlesinger, and Joachim Heberle. https://t.co/VtUS9y5svG
#OPENACCESS: Channel gating in bacteriorhodopsin-like channelrhodopsins with contrasting K+ and Na+ selectivity. Oleg A. Sineshchekov, Elena G. Govorunova, Hai Li, Yumei Wang, and John L. Spudich. https://t.co/Dd3pNZ2aUo
#OPENACCESS: Diverging pH dependence and photocycle dynamics across members of the CryoRhodopsin clade. Sarah Warrelmann, Gerrit H.U. Lamm, Kirill Kovalev, and Josef Wachtveitl. https://t.co/X7sJD5qHnA
Modulation of protein dynamics during a functional cycle of a bateriorhodopsin observed using time-resolved quasielastic neutron scattering experiment provides a first direct observation of protein-dynamics-function correlation. https://t.co/k6R6xOFTzZ
#OPENACCESS: RGS proteins: Potential regulators of mouse melanopsin’s signaling phototransduction cascade across ipRGC subtypes. Lee H. Harkless, K.M. Daly, Grayson P. Ostermeyer, Samer Hattar, R. Lane Brown, and Phyllis R. Robinson. https://t.co/0GJMrGfLPU
#OPENACCESS: Costa et al. combine molecular dynamics simulations, network analysis, and machine learning to study signal transduction in the jumping spider rhodopsin 1, identifying Trp290 and TM6 helix residues as mediators of light-driven GPCR activation. https://t.co/6imQqK1s2W
Antarctic microbes just revealed solar-powered molecular gadgets! Marín et al. discovered novel schizorhodopsins that act like tiny light-driven engines hidden in icy ecosystems. https://t.co/8FlR4Y8wk3
#OPENACCESS: WiChR behaves like a nightclub bouncer for potassium ions! Ohnemus et al. built a quantitative photocycle model showing exactly how light controls this optogenetic gatekeeper. https://t.co/qbcTwXzcji
#OPENACCESS: Tool antibody fragments reveal multiple conformations of the rhodopsin-Gi signaling complex. Filip Pamula, Oliver Tejero, Jonas Mühle, Ralf Thoma, Gebhard F.X. Schertler, Jacopo Marino, and Ching-Ju Tsai. https://t.co/cNZwKejcdE
In the New and Notable "Illuminating rhodopsin activation in real time," Kota Katayama highlights the paper "Activation of visual rhodopsin probed by single-shot transient IR spectroscopy." https://t.co/4orQMHyawe