Bjornsson lab

Physician scientist with focus on epigenetic disorders

[Bjornsson lab @BjornssonL]

Congrats to @KijinJang on this very cool story now available as a preprint:
SARAF represses the mild hypothermia response through the regulation of JUN https://t.co/BKUDfmxHaf

[DMM Journal @DMM_Journal]

@SaraTholl, @BjornssonL & co use a #MouseModel to understand the impact of missense variants on KMT2D function and uncover developmental and perinatal abnormalities in Kabuki syndrome type 1.

Read and share this article for free: https://t.co/YrLQOxCYJw

[Neil Stone @DrNeilStone]

YOU LOVE TO SEE IT

Life expectancy for people with cystic fibrosis going up and up and up and uo

That's what REAL science does.

😍

[Kimberley Anderson @Kimberley1A]

@BjornssonL And glad to have had the opportunity to talk about this more in an interview with AJHG: https://t.co/bGzC6Bw3io

[Kimberley Anderson @Kimberley1A]

Our paper on Pilarowski-Björnsson syndrome is out in AJHG! We show that male sex hormones, including #testosterone, may protect against some phenotypes. Sex differences may also extend to other autosomal genetic disorders.
@BjornssonL https://t.co/SKG6aQNinm

[Bjornsson lab @BjornssonL]

@KijinJang Together, these findings identify SARAF as a new repressor of the MHR and point toward calcium signaling and JUN as very early components of this response.

Congrats again to @KijinJang on a beautiful piece of work!

[Bjornsson lab @BjornssonL]

Congrats to @KijinJang on this very cool story now available as a preprint:
SARAF represses the mild hypothermia response through the regulation of JUN https://t.co/BKUDfmxHaf

[Bjornsson lab @BjornssonL]

@KijinJang Our working model is that SARAF acts upstream of JUN, potentially through its effects on cytoplasmic calcium, with JUN then helping regulate the downstream MHR.

This begins to give us a temporal and regulatory hierarchy for how cells respond to mild reductions in temperature.

[Bjornsson lab @BjornssonL]

@Kimberley1A @Haskolinn_Ak Here is a summary about the article in English: https://t.co/rIyM0aHFRg

[Bjornsson lab @BjornssonL]

Samantekt frá HÍ um nýja grein sem var að koma út í American Journal of Human Genetics: Karlhormón virðast vernda gegn áhrifum sjaldgæfs erfðasjúkdóms https://t.co/tgC7zzuN1N

[Bjornsson lab @BjornssonL]

til hamingju @Kimberley1A sem er nýr lektor hjá @Haskolinn_Ak og Eirný Þöll Þórólfsdóttir hjá Landspítala. Hér er greinin sjálf: https://t.co/MJT5uNML9K

[Leandros Boukas @LeandrosBoukas]

Together with @BjornssonL (and Kasper Hansen, and others) we have spent many years thinking about the molecular basis of Mendelian disorders caused by variants in chromatin regulators.

We have just published a review where we discuss our thoughts: https://t.co/LrGn9nYZjN

[Bjornsson lab @BjornssonL]

We are recruiting a PhD student!!! Deadline for applications is June 16th 2026. Please share with your network and feel free to reach out with questions ([email protected])
PhD position in human genetics https://t.co/oSY2TFW4Si

[Bjornsson lab @BjornssonL]

Loss of KMT2D accelerates hypertrophic chondrocyte differentiation and senescence by increasing mitochondrial ROS production https://t.co/1acZDBLrEi

[Bjornsson lab @BjornssonL]

Congrats @SaraTholl and @AgnesUlfig and Stefán Pétursson on a really cool pre-print suggesting that dysregulated ROS production drives some disease phenotypes in Kabuki syndrome!!! https://t.co/1acZDBLrEi