BMJ Owens

Biopharma | BD | M&A | Immunology | Food | Cooking | Wine. Papers: | Tweets & Opinions are mine

[BMJ Owens @BmjoPhd]

#immunology - can never start too early. 👨🏼‍🔬 Only minor corrections, key revision was that T and B cells ‘have happy eyes daddy’. 2 years and 4 months and already knows more than I did when I first put on my undergraduate🥼 🧪

[BMJ Owens @BmjoPhd]

@habibi_uk Incitement to violence, surely - got to hope that @BrumPolice will take a look at this.

And to add insult to injury she is one of the worst public speakers I’ve ever seen 😂

[BMJ Owens @BmjoPhd]

@jwalkermobile Woah!! Amazing, enjoy!!

[BMJ Owens @BmjoPhd]

@jwalkermobile @pberard @AmauryCarrasco @teamhrc 👏🏻how was the Mouton ‘85 ? It’s my birth year so interested!

[BMJ Owens @BmjoPhd]

Sanity and scientific facts have prevailed: it’s also a supremely crisp, tight and well-written definition. Bravo 👏🏻🫡

[Colin Wright @SwipeWright]

🚨BREAKING: The @HHSGov has just released its official updated statement defining sex for all federal agencies, external partners, and the public!

SEX is a person’s immutable biological classification as either male or female.

FEMALE is a person of the sex characterized by a reproductive system with the biological function of producing eggs (ova).

MALE is a person of the sex characterized by a reproductive system with the biological function of producing sperm.

The new guidance also includes detailed clarifying remarks:

"There are only two sexes, female and male, because there are only two types of gametes. An individual human is either female or male based on whether the person is of the sex characterized by a reproductive system with the biological function of producing eggs (ova) or sperm.

"The sex of a human, female or male, is determined genetically at conception (fertilization), and is observable before birth. Having the biological function to produce eggs or sperm does not require that eggs or sperm are ever produced. Some females or males may not or may no longer produce eggs or sperm due to factors such as age, congenital disorders or other developmental conditions, injury, or medical conditions that cause infertility.

"A person’s sex is unchangeable and determined by objective biology. The use of hormones or surgical interventions do not change a person’s sex because such actions do not change the type of gamete that the person’s reproductive system has the biological function to produce. Rare disorders of sexual development do not constitute a third sex because these disorders do not lead to the production of a third gamete. That is, the reproductive system of a person with such a disorder does not produce gametes other than eggs or sperm."

🔥🔥🔥

[Colin Wright @SwipeWright]

🚨BREAKING: The @HHSGov has just released its official updated statement defining sex for all federal agencies, external partners, and the public!

SEX is a person’s immutable biological classification as either male or female.

FEMALE is a person of the sex characterized by a reproductive system with the biological function of producing eggs (ova).

MALE is a person of the sex characterized by a reproductive system with the biological function of producing sperm.

The new guidance also includes detailed clarifying remarks:

"There are only two sexes, female and male, because there are only two types of gametes. An individual human is either female or male based on whether the person is of the sex characterized by a reproductive system with the biological function of producing eggs (ova) or sperm.

"The sex of a human, female or male, is determined genetically at conception (fertilization), and is observable before birth. Having the biological function to produce eggs or sperm does not require that eggs or sperm are ever produced. Some females or males may not or may no longer produce eggs or sperm due to factors such as age, congenital disorders or other developmental conditions, injury, or medical conditions that cause infertility.

"A person’s sex is unchangeable and determined by objective biology. The use of hormones or surgical interventions do not change a person’s sex because such actions do not change the type of gamete that the person’s reproductive system has the biological function to produce. Rare disorders of sexual development do not constitute a third sex because these disorders do not lead to the production of a third gamete. That is, the reproductive system of a person with such a disorder does not produce gametes other than eggs or sperm."

🔥🔥🔥

[Bella Wallersteiner 🇺🇦 @BellaWallerstei]

27 local authorities have now declared state schools at capacity and can’t absorb private school students (@thetimes). A policy fuelled by envy, punishing private schools and further burdening an already overstretched state system. Appalling.

[DONALD ROSS @vaderbogger]

Dear @RachelReevesMP @Jamie4North speaking as quite a good one man band farmer.

In 2024 I will have contributed nearly £50000 in tax the treasury. I also produce barley which has a tax take of £1.8m and wheat which has a tax take of £4.5m when turned into whisky (all per annum)

[BMJ Owens @BmjoPhd]

@allianzuknews Honestly - what are you talking about! It will be Twickenham, forever and always.

[Jamie Phillips @JNPhillips4]

It won’t really take ‘some getting used to’ because we’re all still going to call it Twickenham.

[Bea Johanssen @bea_johanssen]

@Steven_Swinford The only country in the developed world to tax children's education.

That university fees have been left untaxed simply underlines the spitefulness.

[Kamil Tamiola, PhD @KamilTamiola]

Peptone sponsors Gordon Research Conference 2024 on Biophysics and Biology of Intrinsically Disordered Proteins.

https://t.co/k6P0XO3RZm

[bioRxiv Biophysics @biorxiv_biophys]

Improving Inverse Folding models at Protein Stability Prediction without additional Training or Data https://t.co/gHaImyKLQK #biorxiv_biophys

[Sandro Bottaro @SSadnro]

Preprint here: https://t.co/Vav1Kh4Ml3
@KamilTamiola @carlo_fisicaro @inve_michele @BmjoPhd @PeptoneLtd 4/4

[Michele Invernizzi @inve_michele]

Interested in stability prediction of protein variants? Want to get more out of ProteinMPNN without extra effort?
Check out our latest work at @PeptoneLtd

[Sandro Bottaro @SSadnro]

Proud to share our latest work led by X-less Oliver Dutton! We've demonstrated that inverse folding models can be substantially improved at protein stability prediction without additional training or data. 1/4

[David Brent Fans @DavidBrentMovie]

Teams better than Scotland

[BMJ Owens @BmjoPhd]

@EIE2024 @metpoliceuk @TerrorismPolice It will be ignored, as usual. The dawn raids will be on the homes of those who resist these terrorist scum who live amongst us.

[BMJ Owens @BmjoPhd]

@spectatorindex Go get them boys 🇬🇧 💥

[Egle Kvedaraite @EgleKvedaraite]

🧵 on our recent @NatureComms paper! https://t.co/vcw2IRFjJ8

We were interested in stroma’s role in immune cell homeostasis

And found that stromal lineage (PDRFRA+CD142low/- fibroblast) guides monocyte to macrophage development in human gut

Based on what evidence?
(1/8)

[Egle Kvedaraite @EgleKvedaraite]

How does a monocyte become a macrophage?

We found intestinal stromal cells guide macrophage differentiation via
GM-CSF in human gut!
Now out @NatureComms @karolinskainst
https://t.co/P9Njuz1OXT