Anna Bodzeta

Biophysics, Neuroscience, Microscopy
Postdoc in Grieve lab

[adam grieve @adam_grieve]

Can I ask you to share a PhD advert at Bristol Uni please? Rhomboid proteases play a role in neurons that is essential for life- but it is not characterised. Got a student interested in cell biology, electrophysiology and neurobiology? Send them our way! https://t.co/1aGeWoou9D

[Anna Bodzeta @bodzeta]

Great Summer School with great scientists in beautiful city of Utrecht. Highly recommended.
Also happy to see that one of my 1st images made in Utrecht is still in use 😉

[Harold MacGillavry @hdmacgillavry]

Interested to learn the latest about the development and plasticity of neural circuits? Check out the fantastic program of this Summer School in Utrecht/NL 👇 More info and sign up: https://t.co/3swUWYAe7G

[Anna Bodzeta @bodzeta]

Let’s start new scientific adventure in @adam_grieve lab in Bristol. It is very promising beginning with such view from the lab and green friend on the desk.

[Anna Bodzeta @bodzeta]

Many thank to @hdmacgillavry and @DrFlorianBerger for a great journey into understanding of presynaptic mGluR dynamics!

[Anna Bodzeta @bodzeta]

Finally it is out! Subsynaptic mobility of presynaptic mGluR types is differentially regulated by intra- and extracellular interactions. https://t.co/G1BpdYyWe6

[Anna Bodzeta @bodzeta]

We show that:
- immobilization of mGluR7 at synaptic sites is determined by its extracellular domain while mobility of mGluR2 along the axon is mediated by its intracellular domain.
- dynamics of presynaptic mGluRs are decreased after synaptic activity decrease

[Anna Bodzeta @bodzeta]

We show that:
- presynaptic mGluR2 is highly mobile and localized throughout the axon, while mGluR7 is largely immobilized at presynaptic active zones

[Anna Bodzeta @bodzeta]

These nice neurons do not deserve to be forgotten in the black hole of the backup drive. So, I am sharing them here. @LeicaMicro STELLARIS #FluorescenceFriday

[Anna Bodzeta @bodzeta]

Synapses rule!
Bassoon (green) & Actin (grey) imaged with Elyra 7 with Lattice SIM² @zeiss_micro
#FluorescenceFriday

[Anna Bodzeta @bodzeta]

Everything you want to know about localization of mGluRs, now you can find in our new review 10.1016/j.neuropharm.2021.108799 Thanks to
@NickyScheefhals and @hdmacgillavry
for great collaborations

[Harold MacGillavry @hdmacgillavry]

It has been long in the making but it is online! Our view on how the trafficking and positioning of metabotropic glutamate receptors at pre- and postsynaptic sites shapes synaptic transmission and plasticity: https://t.co/rDuPpREtBw @NickyScheefhals @bodzeta

[Anna Bodzeta @bodzeta]

I am happy to share new insights into nanoscale dynamic of presynaptic mGluRs. Many thanks to @DrFlorianBerger and @hdmacgillavry for fruitful teamwork!

[Harold MacGillavry @hdmacgillavry]

Preprint! In this exciting study spearheaded by @bodzeta with key contributions from @DrFlorianBerger, we present surprising new findings on how the dynamic nanoscale positioning of presynaptic mGluRs is regulated and contributes to synaptic signaling. https://t.co/xnVZ5B8aDG