A great quote from @matthewherper today:
"The reason we canโt get new psychiatric drugs isnโt because the bar is too high,โ said one former FDA official who is critical of #Aduhelmโs approval. โItโs because we donโt understand the fundamental biology.โ
https://t.co/GZrHzwrYaB
@TweetwithQuinn Creating the smokescreen of presentations to create the impression of reliable data perhaps? Of course, none of which is being submitted for peer reviewโฆ
There is a storm coming beyond #LongCovid. In years to come we will be talking about permanent #COVID19 as weโre hit by a wave of chronic / autoimmune/ neurodegenerative disability that we actively encouraged into the population
LONG COVID THREAD:
The people running the BBC Horizon "Great British Intelligence Test" challenge on over 80,000 people took the opportunity to see if they could detect any differences by whether people had had covid or not...
To be clear, none of the #Aducanumab sceptics want to prevent patients getting treatment. We want to make sure snake oil salesmen canโt charge millions for false hope to an extremely vulnerable patient group The consequences of getting this wrong cannot be understated.
The argument โsurely any chance is better than nothingโ is a seductive but dangerous one. Adu is not a benign drug: 1-in-3 will get ARIAs, and it will sap scarce resources from other therapy areas. The benefits are at best unproven, but the harmful consequences are very real.
Very strange statement from the FDA and an approval like Iโve never seen before. The suggestion that AB clearance could be a deciding factor given the repeated failure of amyloid clearance to slow cog decline is on dodgy ground at best #Aducanumab $biib
https://t.co/yZ1KksTI8A
On this important April 1st holiday, we've decided to make available all of our data visualizations from https://t.co/14VDNFGCCp and https://t.co/xscKWHfRSS as non-fungible tokens (NFTs).
The #RaceReport dismissing the idea of structural racism in the UK is a shocking example of bad science masquerading as authoritative insights. Thank god the #BMJ is there to take them to task ๐๐ค
Yet another open letter from the independent advisory committee to the @US_FDA calling for #aducanumab not to be approved on the basis of the data submitted. Strange times. #Alzheimers https://t.co/49mx35wnLZ
A crawling cell making a left turn. What I enjoy watching in this video is the coordination of the leading edge and the myosin II-based contractile system.
#CellBiology#microscopy#SciArt
A great shame as Leicester Uni looks to cut its neuroscience program. Neuroscience on grounds that it doesnโt lead to clinical benefit.
In reality, mental and neurodegenerative illnesses pose our greatest impending needs. Please share and sign this letter ๐ง
@uniofleicester management has decided to axe Neuroscience. Not part of bench to bedside they say.... I have a few (psychiatrist) neuroscientist and psychology friends who might want to have a word. Please sign our public letter.
https://t.co/wlUMSXzykk