Institute for Cardiovascular Physiology

Official twitter account of the Institute for Cardiovascular Physiology | Goethe University Frankfurt am Main | @goetheuni | Director: @Ralf_P_Brandes

[Institute for Cardiovascular Physiology @BrandesLab]

Check out the new preprint from the lab in collaboration with @TheMarcelSchulz on calling RNA-DNA interactions from linker-based sequencing methods! https://t.co/4KdFMKUmGF

[Tim Warwick @tim_warwick]

Do you want to detect #RNA-#DNA interactions from RADICL-seq, Red-C or GRID-seq, but lack a reliable method? Then try RADIAnT, our new statistical framework for calling robust, consistent interactions from RNA-DNA ligation methods https://t.co/3BEH8XmUvZ

[Kurian Lab @KurianLab]

@EVanNostrandLab dive into the new mysteries of snoRNAs in this exciting article.

Includes:
-chimeric eCLiP to map snoRNA-target RNA interactions
- SNORD89 guided 2'-O methylation of U2 leading to splicing regulation
- SNORD3-rRNA processing

https://t.co/b5H9gYBOMC
👏👏👏👏👏

[Institute for Cardiovascular Physiology @BrandesLab]

If you're interested in exploring this pathway, we can help! Reach out and let us know!

Thanks to all supporting authors @PedroMalacarne1 @tim_warwick @TheMarcelSchulz @Ralf_Gilsbach @fleming_ivs + many more & funding bodies @SFB1531 @CPI_ExStra @dfg_public @goetheuni

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[Institute for Cardiovascular Physiology @BrandesLab]

Did you know that there is a second glutamine metabolism pathway that generates α-ketoglutarate?

Check out our new pre-print from @FlaviaRezendeF describing the pathway, now on bioRxiv: https://t.co/DkVYktl8yO

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[Institute for Cardiovascular Physiology @BrandesLab]

This reaction is catalyzed by the ω-amidase enzyme NIT2, which we demonstrate to be a metabolic switch and redox target of oxidative stress.

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[Institute for Cardiovascular Physiology @BrandesLab]

Congrats to @LisaM_Weiss for winning a #DPG2023 poster prize 🎉

[Tim Warwick @tim_warwick]

For anybody at #ISMBECCB2023 interested in mechanisms of regulatory #RNA, I’ll be giving a talk on our recently published method on prediction of RNA-DNA interactions at 12:20 TODAY in the iRNA session! @BrandesLab @TheMarcelSchulz @trr267 @CPI_ExStra

[Marcel Schulz - @[email protected] @TheMarcelSchulz]

Come and see our science in 4 talks over the next three days at #ISMBECCB2023 in #Lyon @dzhk_germany @CPI_ExStra @InstCardReg_FFM

[James A. Oo @JamesAOo7]

Delighted to have been given the opportunity by the @RNASociety to present my work at #RNA23 #RNA2023 in #Singapore. Had great discussions about #lncRNA regulation of #chromatin complexes in #endothelial #gene #expression.

@RNASociety @jrRNAscientists @BrandesLab

[Institute for Cardiovascular Physiology @BrandesLab]

We’re at the #DGKJahrestagung 2023 in #Mannheim today! We’ve already given some exciting talks including the presentation by @Ralf_P_Brandes for the @SFB1531 and the presentation by Frederike Boos on the #lncRNA LINC00607 in #angiogenesis.

[Institute for Cardiovascular Physiology @BrandesLab]

@FlaviaRezendeF and @tim_warwick are in attendance at the Dutch-German Joint Meeting on Molecular Cardiology in Würzburg, ready to share their latest research 🧑‍🔬 watch out for Flávia’s talk and Tim’s poster, and make sure to say hi 👋

[Institute for Cardiovascular Physiology @BrandesLab]

We were thrilled to celebrate Matthias Leisegang's successful habilitation last month, where he gave a great Antrittsvorlesung on #lncRNA in the #cardiovascular system. Thanks to @goetheuni , @CPI_ExStra , @trr267, @dzhk_germany and @UK_Frankfurt for supporting Matthias' work!

[SFB 1531 @SFB1531]

Yesterday we celebrated the launch of our Integrated Research Training Group.🥳 A successful meeting with highly motivated PhD students, great talks, interesting discussions and tasty food. We are looking forward to many exciting years of CRC-specific training! #letsgetstarted

[Institute for Cardiovascular Physiology @BrandesLab]

Thanks to @goetheuni @dfg_public @CPI_ExStra @trr267 @TheBHF @dzhk_germany and others for supporting the project.

[Institute for Cardiovascular Physiology @BrandesLab]

We’ve just published another #endothelial #lncRNA paper in @BasicResCardiol. LINC00607 maintains ERG target gene transcription by interacting with BRG1 to mediate #angiogenesis. Fantastic work from the team! Very well done! 👏🏻 🎉

https://t.co/dml9A24Gwr

[Institute for Cardiovascular Physiology @BrandesLab]

Well done to Frederike Boos @JamesAOo7 @tim_warwick @maduiixeta @MelinaL24 @Bibli_lab @GiuliaKarolin @Hinkel_Lab @bakergroupcvs @reinier_boon @TheMarcelSchulz @Ralf_P_Brandes and everyone else who was involved in the project!

[SFB 1531 @SFB1531]

Looking forward to our SFB 1531 seminar next Tuesday! Save the date and don`t miss @rooij_laura from CeMM talking about #endothelial cell heterogeneity! #cardiotwitter @goetheuni @CeMM_News

[Institute for Cardiovascular Physiology @BrandesLab]

We can’t wait to see so many friendly faces! Plus, our very own @FlaviaRezendeF will be presenting her work on endothelial glutamine metabolism 🧫🧪

[CPI @CPI_ExStra]

27 January 2023 4 - 6 pm @ University Hospital Frankfurt

First joint meeting for basic and clinical heart, kidney and vessel researchers in #Frankfurt to get to know cross-disciplinary topics and methods @BrandesLab @InstCardReg_FFM @IVS_FFM @m_leistner

[Institute for Cardiovascular Physiology @BrandesLab]

Our third #lncRNA paper of the month is out! Terrific work from @JamesAOo7 and the team on such a detailed characterisation of PCAT19 function in #endothelial cells 🧬 with the bonus of some great collaborations as well 🤝

[James A. Oo @JamesAOo7]

🚨Our paper on the role of #lncRNA PCAT19 in #endothelial quiescence, and its implications for #cardiovascular disease, has just been published in @CellReports! 🎉 Featured on https://t.co/yWPe9pZz7x.

#RNA #vascular @CellPressNews #DNA #ScienceTwitter