Single-Cell Profiling Identifies Skin-Resident Memory CD4+ T Cells as a Potential Correlate of Immunity During Staphylococcus aureus Skin Infection https://t.co/AIESjjhrpY
I am so excited to share this work from my PhD which has now been published in @JCI_insight ✨
In this study, we used IFN-γ to induce trained immunity in human macrophages and enhanced their ability to kill M. tuberculosis and MRSA.
Read more here: https://t.co/l2UiMnup82
We are hiring!!! If you are interested in #gdTcells or #Staph this is the position for you!! Post-Doctoral Research Fellow in Immunology at Trinity College Dublin, The University of Dublin https://t.co/tKtagaEdZM
New paper led by @SineadORourke8 discussing the ageing immune response in disease and the potential of the Nrf2-HO-1 axis as a therapeutic target.
Now available online at @FrontImmunol
https://t.co/a1BMcQrNnM
Join us this Friday for #EuropeanResearchersNight in @tcdTBSI and learn how to train your immune system to beat the bugs! Even try your own hand as a part of our pest patrol team to see how well you can defend yourself against bug invasion!🦠🧬🦠 #startatern#irishresearch
Very proud of this latest work from the lab! As we suspected, the immune imprint from a lifetimes exposure to S. aureus might be the reason vaccine have continually failed to drive protective immunity.
Very proud of the latest offering from the lab @tcdbi a huge team effort with @irvinederm @StaphLab but led by Julianne Clowry. A great way to showcase her MD work. S.aureus associated T cell signatures in AD https://t.co/OI35WzyjxZ
Would highly recommend doing a PhD in the host pathogen interaction lab. Rachel is a superb supervisor with an amazing lab, and I am so happy to have done my PhD with her and the team!
Take a note of the key dates announced for the European Congress of Immunology (ECI) 2024!
The 7th ECI will take place in Dublin from 1st to 4th September, 2024.
Visit the link to learn more!
https://t.co/X7bHYYI1Zb
Researchers uncover a novel pathway by which intracellular Staphylococcus aureus can suppress the antimicrobial capabilities of human neutrophils by using the anti-inflammatory adenosine receptor, adora2a (A2aR). Read the article in @mbiojournal: https://t.co/OitV6iZfIC
More insights into how this crafty bug evades the immune system! Culmination of fantastic PhD work by @EmilioVozza@tcdbi S.aureus suppresses pentose phosphate pathway in human neutrophils via adenosine receptor A2aR to enhance intracellular survival |mBio https://t.co/HAAlx5hBtM
I am so delighted to see my paper out in the world! We show that S. aureus drives glycolysis, limiting the pentose phosphate pathway to inhibit neutrophil function and facilitate its intracellular survival. Many thanks to my supervisor @McLoughlin_Lab & to my amazing Co authors!
Staphylococcus aureus suppresses the pentose phosphate pathway in human neutrophils via the adenosine receptor A2aR to enhance intracellular survival https://t.co/vWibGpOxDo