BRIDGE-S Berlin

The BRIDGE-S study led by Ripke lab @ChariteBerlin aims to reveal genetic and environmental factors mediating risk and resilience to schizophrenia.

[stephan ripke @stephanripke]

Excited to share a new attempt to identify drug targets for schizophrenia, lead by @karlheilbron, funded by @AvHStiftung, @dfg_public,, @StanleyCenter, @PGCgenetics  #psychgenomics #schizophrenia https://t.co/f7qnkQ9pt9

[James Walters @drjameswalters]

1/12 Very pleased to finally share the @PGC Schizophrenia Group paper: Mapping genomic loci implicates genes and synaptic biology in schizophrenia https://t.co/IEcUWZVQiF (my first proper thread!!)

[TJ Singh @TarjS]

At long last, I am pleased to say that the SCHEMA consortium’s paper has been published online in @Nature (https://t.co/QkN46s4Vwz): analysis of >120K individuals shows that rare coding variants in 10 genes confer substantial risk for schizophrenia. (1/6)

[Charité - Universitätsmedizin Berlin @ChariteBerlin]

What is the role of genetics in schizophrenia? Thanks to an international collaboration and the largest-ever genetic study on the disorder, researchers from #CharitéBerlin have brought us one step closer to an answer. @nature @bridges_berlin https://t.co/trnSrqbnZV

[Charité - Universitätsmedizin Berlin @ChariteBerlin]

1/2 Welche Rolle spielt das Erbgut bei #Schizophrenie? Forschende der #CharitéBerlin sind der Antwort ein Stück nähergekommen. In internationaler Zusammenarbeit ist die bisher größte genetische Studie dazu entstanden. @nature @bridges_berlin https://t.co/ZpKOcg3fud

[BRIDGE-S Berlin @bridges_berlin]

Wie beeinflusst unsere Genetik das Risiko an einer Schizophrenie zu erkranken? Der @DLF hat nachgeforscht und neben Betroffenen auch unser Studienteam zum Thema befragt. @StephanRipke
https://t.co/GRTXK89o97

[BRIDGE-S Berlin @bridges_berlin]

We are proud to share a first update on data collection efforts in Vietnam, in collaboration with our colleagues at the Hanoi Medical University!

[medRxiv @medrxivpreprint]

Increasing Sample Diversity in Psychiatric Genetics - Introducing a new Cohort of Patients with Schizophrenia and Controls from Vietnam - Results from a Pilot Study https://t.co/11NMWhmuEN #medRxiv

[PGC Consortium @PGCgenetics]

Genome-wide association studies (GWAS) in schizophrenia have identified >300 independent genome-wide significant variants (p ⩽ 5 × 10−8) associated with the disorder.

https://t.co/JyA79W2yGC

[BRIDGE-S Berlin @bridges_berlin]

We really love our new flyer design and look forward to recommence our data collection in the near future!

Wir lieben unser neues Flyer Design und freuen uns schon darauf unsere Datenerhebung bald fortzusetzen! #schizophrenia #research

[PGC Consortium @PGCgenetics]

Want to convert #polygenic risk scores into absolute risks using summary statistics? Check this new tool developed by @cathrynlewis and collegues.

[BRIDGE-S Berlin @bridges_berlin]

We are proud to be part of the latest schizophrenia GWAS — Huge thanks to everyone involved, especially to all participants who engage in our study!

[Danielle @DPosthu]

Finally out! PGC-SCZ3, kudos to the whole working group, but especially to @stephanripke @drjameswalters, Vasa Trubetskoy and Mick O'Donovan

[BRIDGE-S Berlin @bridges_berlin]

We are excited to present our first Poster on BRIDGE-S study procedures at #DGPPN2019

[Schizophrenia International Research Society @SIRSGlobal]

🔬A polygenic resilience score moderates the genetic risk for #Schizophrenia | New study by Hess et al (@PGCgenetics) compares high-risk controls, i.e., "resilient" controls to patients with similarly high polygenic risk scores. @MolPsychiatry: https://t.co/UWIW3BUNc5

[PGC Consortium @PGCgenetics]

Just out: @PGCgenetics Genome-wide association study identifies 30 loci associated with bipolar disorder: Bipolar I strongly correlated with schizophrenia, Bipolar II with major depression. https://t.co/VPpnSHKqH2

[Jordan Smoller @jorsmo]

Exciting new work from @LauraHuckins, Eli Stahl, @DMRuderfer @doctorveera @NancyGenetics @PGCgenetics @hakyim and many others identifying new #schizophrenia risk genes and pathways using transcriptomic imputation in brain. @ISPGnet https://t.co/p5XQohQQnl

[Mental Health Europe @MentalHealthEur]

We just launched our #European & interactive #map of #youth helplines and support services with the precious help of @EuroYouthMH & our members.
. https://t.co/hNMbC2UZ2g #EU #MentalHealth #YouthMentalHealth #SharingisCaring #MentalHealthMatters #Young #EuropeYouth @EU_Social

[Daniel Smith @ProfDanielSmith]

Earlier-onset #depression in #adolescents associated with polygenic risk of #schizophrenia, #ADHD and neurodevelopmental traits. Great new paper in @JAMAPsych by Fran Rice and colleagues @MRCcardiff @PGCgenetics
https://t.co/c8apQLt52X

[BRIDGE-S Berlin @bridges_berlin]

Please also check our brand new BIH-Webseite for other #GWAS-related projects and collaborations! @berlinnovation https://t.co/YOwFHWVoQq

[Dr Chloe Wong @ChloeCWong]

Fantastic illustration of the importance of genetic, environmental AND protective factors in mental illness @J9_Austin. #WCPG2018

[PGC Consortium @PGCgenetics]

Using #ALSPAC data she shows that both early and late adolescent onset #depression are associated with #depression PRS but the early onset group also associated with #schizophrenia and #adhd PRS. Really interesting paper. Also @anita_thapar1