Bennett Shaw

Medical student @dgsomucla / former researcher @mgh_id @sabeti_lab / science and running / tweets are my own

[CBS LA @CBSLosAngeles]

First locally-acquired case of dengue virus discovered in Pasadena https://t.co/E1xl48JbXi

[Bennett Shaw @bshawrunnin]

Stay tuned as our innovative team @UCLA_Pathology @UCLA_ID continues to explore the many advantages of routine pathogen sequencing in the clinical microbiology laboratory! (6/6)

[Bennett Shaw @bshawrunnin]

The latest from our Molecular Microbiology and Pathogen Genomics lab here at @dgsomucla is now out in @Micro_MDPI @MDPIOpenAccess. (1/6) https://t.co/C9kWVUEVbf

[Bennett Shaw @bshawrunnin]

SNP distance analysis revealed that the closest link between any two isolates was 96 SNPs, far greater than the 10 SNP threshold indicating transmission within the last two years. Bottom line: no evidence of local MTB transmission within our patient population. (5/6)

[Bennett Shaw @bshawrunnin]

We hypothesize that mechanisms of antimicrobial resistance may vary across subspecies, and we hope to continue this work by using WGS to study MAC subspecies-resistance dynamics. Stay tuned! (4/4)

[Bennett Shaw @bshawrunnin]

Excited to share some of my latest work with the UCLA clinical micro lab genomics team using WGS to identify Mycobacterium avium complex (MAC) subspecies using whole genome sequencing. (1/4)
https://t.co/xKN3OeViPW

[Bennett Shaw @bshawrunnin]

While MAC can infect many tissues, we show that M. avium subsp. homonissuis is the most commonly isolated subspecies from the lower respiratory tract while M. intracellulare subsp. chimaera is most often found in soft tissue wound infections. (3/4)

[Bennett Shaw @bshawrunnin]

Day 5 prenatal counseling edition. No soft cheeses in pregnancy due to Listeria risk is incomplete. Evidence says that melons and hummus are high risk foods to be avoided and locally prepared foods (delis and such) are higher risk for outbreaks.

[Bennett Shaw @bshawrunnin]

Back by popular demand: 1 learning moment from each day of Family Medicine rotation. Thank you to those encouraging me to do more of these!

[Bennett Shaw @bshawrunnin]

Day 2: Endometritis should be considered in ddx of abdominal pain. Risk factors include any opening of cervix and rupture of membranes including recent menstrual bleeding, miscarriage, and vaginal delivery. More peds/obgyn learning moments on the way…

[Bennett Shaw @bshawrunnin]

IM Day 17: 5 classes of 🫁 HTN:
1) PAH (idiopathic) 2) Left heart disease 3) Lung Disease (COPD, emphysema, IPF, etc) 4) chronic thromboembolic events 5) unknown / secondary to other disease w/ unknown mechanism

[Bennett Shaw @bshawrunnin]

IM Day 16: EPO (erythropoietin) is contraindicated in patients with anemia and active malignancy because it potentially accelerates tumor growth and jeopardizes survival.

[Bennett Shaw @bshawrunnin]

IM Day 15: In an immunocompromised host, normally harmless organisms can cause serious damage. Among them is Strongyloides, a roundworm that can cause a life threatening infection. In the US it is most commonly seen in immigrant populations.

[Bennett Shaw @bshawrunnin]

And it can produce blood cells and regrow after trauma and other really cool immunology stuff. Often removed after MVA trauma due to bleeding risk, yet people often live normal happy healthy lives without a spleen.

[Bennett Shaw @bshawrunnin]

IM Day 14: Had a patient with new afib, multiple lacunar infarcts, and splenic hematoma thought to be also due to an embolus. This gives me a chance to talk about my favorite organ: the spleen!

[Bennett Shaw @bshawrunnin]

Hematologic role: in charge of ‘quality control’ of blood cell lines. Gets rid of old, damaged, deformed cells and fascinatingly can actually make blood cells when your bone marrow isn’t working well.