The first trial of creatine in Alzheimer’s disease was just published and the results are big.
Patients took 20 grams of creatine monohydrate daily for 8 weeks.
Brain creatine levels rose 11%, and cognition significantly improved across multiple domains, including memory, reading, and attention.
Nearly every participant stuck with the protocol. No drug, no major side effects.
Caveat: it was a small, single-arm pilot study with no placebo group, so results must be interpreted cautiously.
Still, encouraging signs from a humble supplement.
La agresividad fue clave para darle un vuelco al partido con buenas actuaciones de Pérez Guedes y Calcaterra. Pero no nos quedemos con la foto final: Universitario se está convirtiendo en un equipo reactivo, lo cual es peligroso. Y que se hace goles (y muy tontos, no Riveros?)
🙌 Introducing native 3D for the Apple Ecosystem!
🌟 3D Embeds for iOS, iPadOS, macOS
⚡️ Upcoming support for visionOS/Vision Pro
🎄 Native App Generation
✨ UI scenes for the 3D space
🎇 Particles
Spline is now multi-platform & multi-dimensional
https://t.co/95t6fsULNP
We are incredibly excited to announce the final close of NXTP Fund III – a $98m vehicle to continue to partner with the best early-stage B2B entrepreneurs in LatAm.
The successful raise is a testament to our firm commitment to the entrepreneurs in the region and the incredible opportunity we see to build large tech-enabled companies and transform the way business is done in the region.
We are very grateful to all the entrepreneurs in our portfolio for giving us the opportunity to work with you and for the unwavering support of our LPs, many of whom have been investing with us for over a decade. Thank you for your trust!
Read more about our Fund III on TechCrunch: https://t.co/vULdeERn9p
Meet Naiara Lew @naiaralew and Oscar Caipo @caiposc, NXTP’s Mexico Team!
Before joining NXTP in 2021, Naiara worked as an Investment Banking Analyst at Goldman Sachs. Before joining Goldman, she also worked as a Financial Due Diligence Consultant at PriceWaterhouseCoopers. Naiara has a MSc in Finance and a BA from the Universidad Torcuato Di Tella. If you want to discuss B2B Marketplaces or Logistics Tech, meet Naiara at Cafe Comunidad in Condesa.
Oscar was part of the founding team at Riogrande (YC W21) and worked as a Strategy & Finance Associate. He started his career in New York working at Bank of America in the Latin America Investment Banking desk. Oscar holds a B.B.A. in Business Administration with a concentration in Finance from the University of Notre Dame. If you want to discuss B2B FinTech or Vertical SaaS, meet Oscar at La Zaranda in Roma Norte.
Probablemente esta noche la U venza a Comercio y quizás elimine a Corinthians, pero nada borrará el pésimo manejo del club sobre el Caso Avellino, con un comunicado propio de épocas que parecían superadas. Las amenazas a Barco son solo el colofón de una semana triste y vergonzosa
I talked to a growth stage VC who believes that the headline prices for deals getting done don't reflect "true enterprise value".
Many deals getting done are structured as senior preferred equity with a healthy coupon.
It's worth internalizing that this is the same as "debt with an equity option". The new investor earns a healthy return unless the company becomes insolvent. And if the headline price is "too high" then their return comes at the expense of earlier investors and employees.
This isn't a surprise, but it reflects the fact that headline prices need to come down substantially before clean equity is available for mid/later stage startups.