@whsource Modern wines have tons of sulphites and aren't fermented on the grape so you won't notice much. It's more important for traditionally made wines. The difference is very noticeable, especially if it's decanted.
@FatEmperor High methyl intake is associated with badness, but only very weakly, cancer, etc. It may be a genetic thing if you're a high methylator, or related to cheap vitamin intake, folic acid, cyanobalamin, etc.
@gerdosi Sorry, what i meant was that weight gain or loss has no impact on health. So the study results are meaningless. It's your health that has an impact on weight gain.