Kristopher Sarosiek

The Sarosiek Lab @HarvardChanSPH studies the regulation of #apoptosis in human development and diseases.

[Dana-Farber’s Breast Oncology Center @DFCI_BreastOnc]

Check out this @Nature paper 👉 A glucocorticoid-FAS axis controls immune evasion during metastatic seeding.
👉https://t.co/ZqiQjqaN0J
@debog93 @PBaldominos @laken66174680 @elmayermd @CellDeathLab @EMittendorfMD @JudithAgudo1 @HSCRB #BreastCancer #TNBC

[Kristopher Sarosiek @CellDeathLab]

Congrats Monica, Judith and team! We were so glad to contribute to this work, which has wide-reaching implications for how we treat cancers. Looking forward to continuing the collaboration and overcoming this resistance.

[Judith Agudo @JudithAgudo1]

Metastasis kills most cancer patients and grows from invisible seeds. How do these seeds escape from attack by immune cells? These seeds harness stress hormones!🤯
⁦thanks to ⁦@nyscf⁩ ⁦@parkerici⁩ for their support. Today at ⁦@Nature⁩ https://t.co/rMKnHEqQwb

[Dr. Anthony Letai @NCIDirector]

My daughter is in an MSTP program, so I hear about the challenges firsthand: the long hours,
the uncertainty, the pressure.

To all our early career scientists, I want you to know that what you're doing matters. Your perseverance today becomes tomorrow's treatments. Keep going.

[Joan Montero @JoanMonte]

If you are interested in pursing a PhD in precision medicine in my lab (https://t.co/BV72RAPEEY) & you meet one of the following conditions: completed undergraduate studies, master within the European Higher Education Area & are admitted to a doctoral program in Catalonia, DM me

[Alex's Lemonade Stand Foundation @AlexsLemonade]

We had the zest time at tonight's #LemonBall!💛🍋💃

To everyone who attended, we cannot thank you enough for making this Lemon Ball extra sweet. Thank you for all that you have done and continue to do for kids with cancer. Special thanks to our outstanding presenting sponsors ALDI USA, Applebee's Neighborhood Grill + Bar, Northwestern Mutual and Volvo Car USA, and all the Lemon Ball sponsors, benefactors, supporters, volunteers and friends who made this night possible.

Let's keep making progress for children with cancer all year long!🎉

[Anthony Letai MD PhD @DrTonyLetai]

I am sharing a quick update for those who may not have seen this yet. As of 9/29/25, I have had the honor of serving as Director of the National Cancer Institute. I will be sharing updates on cancer research progress from @NCIDirector. Feel free to follow me there.

[Dr. Anthony Letai @NCIDirector]

Clear, trustworthy information is essential during a cancer journey. If you or someone you care for has questions about cancer or cancer care, @theNCI’s Cancer Information Service can help. Call 1-800-4-CANCER or visit https://t.co/QPovDN0aUY

[Kristopher Sarosiek @CellDeathLab]

➡️Join our upcoming BCDI discussions on #celldeath as a modulator of intestinal inflammation from Pedro Saavedra @Northeastern and blocking ferroptosis to prevent pancreatitis from Zhe Cao from @HarvardChanSPH!

Monday January 5th at 3PM @harvardmed. https://t.co/uOJiL148QG

[Peter Tsvetkov @ptrtsvetkov]

Join us on December 1, 3–4 pm, for another great set of talks on ferroptosis and apoptosis at the Boston Cell Death Initiative @BIDMC_CancerCtr.

[Kristopher Sarosiek @CellDeathLab]

➡️Join our upcoming BCDI discussions on the role of ferroptosis in autism led by Sundari Chetty @harvardstemcell and targeting apoptosis to overcome cancer chemoresistance led by Xingping Qin @HarvardChanSPH

Monday December 1st at 3PM @harvardmed Quad. https://t.co/uOJiL148QG

[Kristopher Sarosiek @CellDeathLab]

@AlexsLemonade Can you host one of these in Boston?? I bet you’d get a huge turnout and I’d certainly love to support the event.

[Alex's Lemonade Stand Foundation @AlexsLemonade]

The 2025 Young Investigator Summit brought childhood cancer researchers together to discuss the future of their work in a changing landscape. These Alex's Lemonade Stand Foundation-funded scientists receive YI Grants early in their careers, a critical time to establish research projects that will hopefully lead to more cures for kids in the long term.

Thanks to all researchers and staff who attended and to @NM_Financial for sponsoring this year's YI Summit!

[Peter Tsvetkov @ptrtsvetkov]

Don’t miss our next BCDI meeting! 🧠 GPX4 in neurodegeneration—Adam Wahida (Helmholtz-Munich; visiting @MGHCancerCenter, @HarvardChanSPH) 🧬 Targeting phosphate homeostasis in cancer—Daniel Bondenson (@UMassChan) 📅 Mon Nov 3 | 3PM | @harvardmed Quad 🔗 https://t.co/sl332L9g5I

[Kristopher Sarosiek @CellDeathLab]

➡️Join our next BCDI meeting for exciting discussions on immune-competent organoid brain tumor models from Xin Tang @BostonChildrens and immune suppression in ovarian tumorigenesis from @TanjinaKader @harvardmed! Monday Sept 8th at 3PM @ Harvard Med Quad. https://t.co/uOJiL148QG

[Alex's Lemonade Stand Foundation @AlexsLemonade]

We want YOU 🫵 to join The Million Mile Challenge to help kids with cancer! Every September for Childhood Cancer Awareness Month, thousands of supporters walk, run, and cycle to help reach our collective goal of moving a million miles and raising millions for childhood cancer research.

YOU have the power to make a difference. Register for free and challenge your friends and family to join your team> https://t.co/dpjfOr9i2Y

[Henning Willers, MD, FASTRO @HenningWillers]

📢Informative #radbio review in @IJROBP ⚠️

MYC is an enigmatic oncogene impacting #radiotherapy responses in complex ways. This work focuses on novel approaches for MYC inhibitors.

@sueyom @CellDeathLab

https://t.co/xe5AwLjBHg

[Lorenzo Galluzzi @deadoc80]

Glad to share our latest @sigtrans_sttt review on #cancer #stemness and #epigenetic. Kudos to @ClaudiaGalassi9 for taking the lead, not possible w/o critical input from Ilio Vitale #offttwitter and @ManelEsteller @CarrerasIJC @FoxChaseCancer Free at https://t.co/F461qTWV44

[Nature Reviews Molecular Cell Biology @NatRevMCB]

New Online! Regulation of inflammatory processes by caspases https://t.co/gHudIkB5Oa

[Kristopher Sarosiek @CellDeathLab]

Herculean effort from @deadoc80 and team to COMPREHENSIVELY review how #caspases promote or suppress inflammatory signaling. Recent discoveries show that caspase signaling, and ultimately organismal responses, are nuanced and context-dependent. #apoptosis #inflammation

[Lorenzo Galluzzi @deadoc80]

Here comes our latest @NatRevMCB review on the control of #inflammation by #apoptosis, #pyroptosis and #caspases! Kudos to @RuthSAnyc and @Mbv26 for the heavy lifting! Not possible w/o input from @CellDeathLab and Doug Green!! @FoxChaseCancer @HarvardChanSPH @StJude

[Lorenzo Galluzzi @deadoc80]

@NatRevMCB @RuthSAnyc @Mbv26 @CellDeathLab @FoxChaseCancer @HarvardChanSPH @StJude Available at https://t.co/BAgvBYe9Sd