Ajith Karunarathne, PhD (he/him)

Biochemist, molecular cell biologist, associate professor @SLUChemDept, editorial board member @PLOSOne and @jbiolchem, PI in Molecular Cell Lab @SLUChemDept

[Ajith Karunarathne, PhD (he/him) @Cellphotochem]

https://t.co/ZmYagPpyYG
"බුද්ධි ගලනය" ඇත්තක්ද?වැරද කාගෙද?

[Alexei Demchenko, PhD, ACSF @glycoworld]

Come and join us at SLU Department of Chemistry. We seeks applicants for a tenure track assistant professorship in the fields of physical chemistry, biochemistry, or biophysical chemistry, broadly defined. Have questions? Please contact Prof. Mak [email protected] @SLUChemDept

[Jen Heemstra @jenheemstra]

Research inherently comes with uncertainty. The key is to focus on what we can control.

Not every idea will work right away in lab, but we can troubleshoot and then try again.

Not every proposal will be funded, but we can stay open to feedback to keep sharpening our ideas.

[Slava Bobrov @slava__bobrov]

How big are the cells? Microorganisms in perspective

[bioRxiv @biorxivpreprint]

Spatiotemporal optical control of Gαq-PLCβ interactions https://t.co/zTxAiQbWTf #bioRxiv

[Ajith Karunarathne, PhD (he/him) @Cellphotochem]

Happy to share our latest work now spatiotemporal optogenetic control of Galphaq signaling. You can access the preprint version in biorxiv now.

https://t.co/XscMPIE8Cl

[Ajith Karunarathne, PhD (he/him) @Cellphotochem]

https://t.co/Le3hM2lGkL

[bioRxiv @biorxivpreprint]

CaaX-motif adjacent residues control G protein prenylation under suboptimal conditions https://t.co/urEtk0p8O9 #bioRxiv

[Ajith Karunarathne, PhD (he/him) @Cellphotochem]

Happy to announce our latest research live on biorxiv as a preprint!

[bioRxiv @biorxivpreprint]

CaaX-motif adjacent residues control G protein prenylation under suboptimal conditions https://t.co/urEtk0p8O9 #bioRxiv

[Young Group @ UToledo @YoungGroupChem]

at these systems, recently culminating in our ability to "turn off" the C–H activation by exploiting the rate determining nature of C–H activation and switching to a coupling partner that worked under milder conditions: https://t.co/3780wUogcB

In the current work, we... (3/5)

[Young Group @ UToledo @YoungGroupChem]

products. The reason for this is that in situ-formed nanoparticles were found to give the Mizoroki–Heck coupling products, while C–H activation was favored by homogeneous Pd species: https://t.co/imWTnh9tLi

Following up on this work, we published several studies looking... (2/5)

[Ajith Karunarathne, PhD (he/him) @Cellphotochem]

@YoungGroupChem Delighted to be a part 🤩

[Young Group @ UToledo @YoungGroupChem]

Happy to share our recent preprint: https://t.co/9mMcXV8fuy

Having worked on the Pd-catalyzed functionalization of allylamines for a few years, we've struggled with the fact that insertion reactions were faster than C–H activation reactions, giving trans rather than cis... (1/5)

[Ajith Karunarathne, PhD (he/him) @Cellphotochem]

Our latest article was just published in Nature Scientific Reports! Congratulations to my current and former team members for unveiling crucial signaling mechanisms published here underlying GPCR physiology and pathology!
https://t.co/IVDdpv7Zcl

[Ajith Karunarathne, PhD (he/him) @Cellphotochem]

Happy to share the preprint version of our latest article on Molecular regulation of GPCR-G-protein-governed PIP3 generation and its adaptation https://t.co/1zTH0nQVD4

[Ajith Karunarathne, PhD (he/him) @Cellphotochem]

@SLU_Official @SLUChemDept @WUSTLmed @WashUanesthesia @usjp @SJPChemistry @jbiolchem
G protein gamma subunit, a hidden master regulator of GPCR signaling https://t.co/6xm5U6X61i

[Ajith Karunarathne, PhD (he/him) @Cellphotochem]

I am excited to congratulate the latest Ph.D. recipient from my @cellphotochem at the @UToledo, Dr. Mithila Tennakoon! She defended her dissertation titled "Molecular regulation of G protein localization and its pharmacological implications" exceptionally well. @chemistrytoledo

[UToledo NSM @UToledo_NSM]

Shout out to Mithila Tennakoon, @UToledo Ph.D. student @Cellphotochem @ChemistryToledo who received a third-place award at #MUACC2021 hosted @OSU_CBC on October 15-17 for her poster titled “G Protein C-tail Drives Prenylation Efficacy and Statin Sensitivity”. #UToledo #UToledoNSM

[Ajith Karunarathne, PhD (he/him) @Cellphotochem]

Postdoctoral position in protein engineering & optogenetics @ Ajith-Lab at @UToledo, USA. Send cover letter, CV, & a list of three references in one pdf to https://t.co/26FPqPV6Q6. Also, email it [email protected]. Review start: 8/30/21.
@chemjobs2, @PostdocJobs

[Ajith Karunarathne, PhD (he/him) @Cellphotochem]

Postdoctoral position in protein engineering & optogenetics @ Ajith-Lab at @UToledo, USA. Send cover letter, CV, & a list of three references in one pdf to https://t.co/26FPqPV6Q6. Also, email it [email protected]. Review start: 8/30/21. @UToledo_NSM @ChemistryToledo