OpenAI's AI broke out of a locked test environment, got onto the internet, and hacked into Hugging Face's servers. It did this entirely on its own. No human told it to.
Here's what happened in plain English.
OpenAI was testing how good its newest AI models are at hacking. They put the AI on a locked computer with no internet access and gave it a cybersecurity challenge to solve.
The AI couldn't solve it the normal way. So it started looking for a way out.
It found a software bug that nobody knew about. It used that bug to escape the locked computer and get onto the internet.
Once online, the AI figured out that Hugging Face, a platform where AI companies store their models and data, might have the answers to its test.
It found stolen login details and discovered another unknown bug in Hugging Face's software. It combined both to break into their servers and grab the test answers.
It did all of this to cheat on a test.
Hugging Face's security team caught it and shut it down. Both companies are now working together on the investigation.
The part that should get your attention is that nobody programmed any of this. The AI picked its own targets, chained together multiple attack methods, and pulled it off across two different companies' systems without a single human telling it what to do.
@Barclays, how is a 2026 credit card experience this bad? No app access, no online banking, no digital statements and supplementary cardholders locked out too. Feels pre-internet. Slow, painful, impossible to budget. Cancelling immediately. #Barclays#Banking#CustomerExperience
This is the biggest irony in tech history.
Microsoft beat revenue estimates. Stock plunged 11%, wiped out $400 BILLION in market cap.
Salesforce reported growth. Stock fell 5.6%.
ServiceNow beat earnings. Stock crashed 11%.
SAP beat projections. Stock dropped 16%.
Entire software sector entered bear market territory. Down 22% from peak.
These are the companies everyone said would WIN from AI.
They spent billions BUYING AI companies.
ServiceNow: $7.75 billion for Armis.
Salesforce: $8 billion for Informatica.
They launched AI products. Built AI workflows. Hired AI teams.
And the market said: You're all dead.
Because investors just realized something nobody wanted to admit:
AI doesn't make software companies stronger.
AI makes software companies OBSOLETE.
Morgan Stanley:
"In an environment of heightened investor skepticism, stable growth falls short of shifting the narrative."
Good earnings aren't enough anymore.
The market is pricing in a world where AI replaces the software these companies sell.
ServiceNow CEO tried defending on the earnings call: "AI needs workflow orchestration. ServiceNow is the gateway to this shift."
Market response: 11% crash.
Because here's what he didn't say:
If AI can write code, automate workflows, and generate apps at a fraction of the cost, why would anyone pay $50,000 per year for enterprise software licenses?
The per-seat pricing model that made SaaS companies rich is getting murdered by AI efficiency.
One AI agent replaces 10 seats.
One prompt replaces months of custom development.
One LLM call replaces entire software categories.
Klarna already proved it. CEO said they pulled Salesforce out of their stack.
Built everything themselves using AI.
And that's just the beginning.
The software apocalypse hit hardest on companies that INVESTED IN AI:
Atlassian: down 12.6%
Intuit: down 7.8%
HubSpot: down 11.5%
Zscaler: down 6.3%
Meanwhile, the companies ENABLING AI made money:
Nvidia: up
Semiconductor stocks: surging
Memory firms: rallying
The divide is brutal.
Hardware companies print cash.
Software companies get destroyed.
Because in an AI-first world, you need GPUs to build the models.
But you don't need software subscriptions when the AI builds the software for you.
Jim Cramer called it the "P/E multiple compression crisis."
Translation: Investors don't care about earnings anymore.
They care about whether your business model survives the next 5 years.
And right now software business models look doomed.
They're literally stuck:
If they DON'T invest in AI, they fall behind.
If they DO invest in AI, they cannibalize their own products.
It's a death spiral with no exit.
ServiceNow spent $12 BILLION on acquisitions in 2025 alone.
Trying to buy their way into relevance.
And yesterday the market cooked them.
The craziest thing to me tho...
Most software companies beat earnings.
Revenue was solid. Growth was fine.
But it didn't matter.
Because the market stopped pricing software on what it earns TODAY.
It's pricing software on what it's worth in a world where AI does the job for free.
And in that world these companies are worth nothing.
This is the biggest sector repricing since 2008.
$500 billion in market value gone in ONE DAY.
And it's not stopping.
Because every company watching this is thinking the same thing:
"If I can replace ServiceNow with 3 AI agents and save $10 million per year, why wouldn't I?"
The answer used to be: "Because you need enterprise-grade reliability."
But now? AI agents are getting reliable. Fast.
Software companies just realized they're competing with open-source models that cost $0.02 per 1,000 tokens.
You can't win a pricing war against free.
The companies that spent BILLIONS preparing for AI are getting killed BY AI.
What an irony.
DAVOS: THE SHORT VERSION
(NO FLUFF)
(Sorry for the photo, nothing personal to my EU friends)
Let me give you the compressed version of what actually happened at Davos.
🇺🇸 Donald Trump
What he said (synopsis):
•America is done subsidizing bad trade deals
•Sovereignty matters more than global consensus
•Greenland is strategic and negotiable
•Leverage beats lectures
Tone:
Direct. Blunt. Very American.
Observation (mine, not medical):
He looked very tired.
Not weak, just worn down.
I genuinely hope he’s okay.
Impact:
He reset the room.
Davos stopped being theoretical.
⸻
💰 The “Fed guy” — Scott Bessent (U.S. Treasury)
What he said (synopsis):
•Markets aren’t panicking
•U.S. debt is fine
•Europe is overreacting
•“Take a breath”
Translation:
America isn’t scared, and we’re not slowing down to make Europe feel comfortable.
Why Europe hated it:
They expected reassurance.
They got dismissal.
⸻
📦 Trade — Jamieson Greer (USTR)
What he said (synopsis):
•Tariffs are not radical, they’re historical
•Free trade hollowed out the U.S. middle class
•Balance matters more than ideology
Translation:
Globalism didn’t fail accidentally.
It failed structurally.
Why Davos didn’t like it:
He challenged the core religion of the room.
⸻
⚡ Energy — Chris Wright
What he said (synopsis, reported from closed sessions):
•Energy security comes before climate theater
•Oil and gas still matter
•Supply beats slogans
Important:
These remarks were reported from closed-door meetings.
I cannot confirm a public Davos speech transcript.
Why it mattered:
It exposed the gap between elite narratives and physical reality.
⸻
🔥 Howard Lutnick — Commerce Secretary
What he said (reported, not verbatim):
•Europe’s energy policy is delusional
•Coal works when renewables don’t
•America isn’t apologizing for winning
Reaction:
Jeers. Walkouts.
Christine Lagarde reportedly left early.
Was it harsh?
Yes.
Even by American standards.
Was it intentional?
Absolutely.
Sometimes clarity requires friction.
⸻
🇫🇷 Emmanuel Macron
What he did (synopsis):
•Warned against U.S. “coercion”
•Framed America as destabilizing
•Played the familiar moral authority card
Reality:
Same speech.
Same posture.
Different decade.
Boring.
⸻
🇪🇺 Ursula von der Leyen
What she said (synopsis):
•Europe will lead the “largest free trade bloc in the world”
•Focus on South America / “Latin America”
•Regional partnerships are the future
Translation:
Globalism isn’t dead,
it’s being rebranded.
What this really was:
Globalism light.
Same system.
New label.
America not invited.
⸻
🇨🇦 Mark Carney
Now this part matters.
Trump warned Mark Carney to watch his tone in public remarks about U.S. policy.
Trump wasn’t tolerating proxy criticism, even from allies.
His speech was the same as always: Globalist Chit chat
⸻
THE BIG PICTURE (WHY THIS WAS A SMACKDOWN)
Europe wasn’t offended because Americans were rude.
Europe was offended because America stopped pretending.
Davos runs on:
•Polished language
•Managed outcomes
•Consensus without accountability
America showed up with:
•Leverage
•Direction
•Consequences
Yes, it was harsh.
Yes, it was uncomfortable.
But here’s the thing:
After all the outrage…
after all the editorials…
Deals still happened.
Including Greenland.
Yes: Trump and Greenland came to an agreement.
See the structure European leadership?
Try it sometime.
Intent.
Planning.
Action.
Delivery.
Results.
"Why does our top performer get the worst reviews?" the boss asked.
I was reviewing their annual performance data.
"Show me," I said.
She pulled up the ratings.
Diana: 2.8 out of 5.
Below average on "collaboration."
Low marks for "team player."
"What's her actual performance?" I asked.
"Exceeded every target.
Landed our biggest client.
Trained three new hires."
"So why the low scores?"
"Her peer reviews are dragging her down."
I scanned the comments.
"Too direct."
"Challenges ideas too much."
"Not supportive enough."
"Let me talk to Diana," I said.
"I used to give honest feedback," Diana told me.
"Said our pricing model was broken.
Got dinged for 'negativity.'"
"What happened with the pricing?"
"They finally fixed it six months later.
After we lost two major accounts."
"What else?"
"I questioned why we needed
eleven approvals for a simple contract change.
Manager said I wasn't being collaborative."
"Are you still giving feedback?"
"No. I learned my lesson.
Now I smile. Nod. Say everything's great.
My reviews are improving."
"But nothing's actually improving?"
"We're making the same mistakes.
Just with better vibes." She chuckled.
I went back to the boss.
"Your review system doesn't measure performance," I said.
"It measures compliance."
"That's not true."
"When was the last time someone
got promoted for challenging bad ideas?"
Silence.
"When did someone get rewarded for preventing a mistake?"
More silence.
"You've trained your best people to stay quiet.
And your mediocre people to stay nice."
A few months later, they redesigned the system.
Added a category: "Constructive Challenge."
Points for identifying problems early.
Rewards for preventing costly mistakes.
Diana got promoted.
"What changed?" I asked the boss.
"We stopped confusing agreement with alignment.
Stopped mistaking silence for harmony."
"And?"
"Turns out our 'difficult' people
were our most valuable.
They actually cared enough to speak up."
Here's the truth about performance reviews:
Most companies don't reward performance.
They reward performance theater.
The person who says the meeting was great
beats the person who says it wasted an hour.
The person who agrees with bad ideas
beats the person who prevents disasters.
You think you're measuring contribution.
You're measuring conformity.
And your best people?
They've already figured out the game.
They're just deciding whether to play it
or find somewhere that values truth over comfort.
This is absolutely worth your time. Really shows up British politicians for the intellectual pygmies they really are. JD Vance excoriates the whole premise behind globalisation.
I’ve moved my entire family to Dubai.
We can live here for life.
Our kids can be born here.
Their kids can be born here too.
And none of us will ever be citizens ❌
No voting.
No control over the system.
And that’s exactly why it works.
Only around 9% of the population are Emirati citizens.
Yet they control their borders, their taxes, their culture, and their future.
Imagine if anyone could move here and vote.
It would slowly become the UK.
High taxes.
Broken systems.
Short term thinking.
Dubai does the opposite.
It attracts talent.
It attracts capital.
It attracts ambition.
But it never gives up control.
You’re free to earn.
Free to build.
Free to invest.
But ownership of the country stays with the people who built it.
That’s not oppression.
That’s intelligent design.
Most countries sell control for votes.
Dubai protects control and invites value.
Do you agree?
Would you move your family to Dubai?
PS: There is one exception people always mention.
If one of my daughters married an Emirati, she could apply for citizenship.
The catch?
7 years of marriage if they have children.
10 years if they don’t.
Nothing is given easily here.
And that’s exactly the point.
#dubai #uae #dubailife #wealth #freedom #future
Tax. We’ve all become so used to it, we forget how much we’re actually paying. It is relentless, even beyond death. And for what? If we had a semblance of functioning public services, I could maybe stomach it. But we don’t, so what are we actually paying all of this money for?
We are subject to Scandinavian levels of tax for third-world levels of competence - what a toilet deal.
Earn a salary. Income tax, a fifth gone before we’ve even started. National insurance, more on top of that. What for? A ‘world-class’ health service? The NHS? Ha. Good luck.
Even getting to work costs - taxes on buying a car, running a car, insuring a car. Vast amount of road tax. Is that being well spent? Unless you want potholes you can paddle in, the answer is no. A road network built for half the amount of cars. How’s that going? It takes twice as long to get anywhere. Fuel duty and tax on insurance - whack that on top too. Congestion charges, tolls, fines and more. It goes on and on and on.
Forget getting the train, that’ll cost twice as much and never runs on time - a season ticket into London costs thousands. Unaffordable. Yet the trains so often run empty? Maybe that system isn’t working…
VAT on anything that moves - getting taxed to buy products/services, from already taxed money.
Tax, tax, tax, tax, tax, tax. Then more tax.
Did you go to university? Your ‘loan’ isn’t loan, it’s a tax. Interest is so sharp, you’re just paying that off each month. Hundreds gone, to pay for a sociology degree a decade ago. Ouch. Why are we saddling our youngsters with so much debt, with so much interest on top of that? Madness.
Manage to put a few quid away to save? That gets taxed too - ISAs will be under attack in the budget. Profit made on successful investments, what happens? You guessed it. Tax.
Somehow you’ve scrabbled a deposit together for a property. Well done.
Paying half a million quid for a semi-detached? Not cheap. Stamp duty means you get slapped for thousands. Obviously first time buyer exemptions mean less and less as house prices soar.
You’re in the house. Great news. Or so you thought. Council tax. Going up seemingly by 5% every year. Thousands of pounds a year. For what? To collect the bins? Really? Don’t forget the extra costs to have your garden waste removed. Brilliant.
More insurance taxes, and of course VAT on any improvements you want to make. Bills soaring, with tax slapped onto every corner of it - green levies and the rest.
How depressing. Time for a pint.
Alcohol duty. Because of course. Why wouldn’t they throw extra tax on it? I’m not a smoker, but the same applies. Even holidays. Air passenger duty to put a few extra quid onto the price of a trip away. Just for good measure.
You’re limping on through. Maybe you decide that starting your own business is the way to go?
You get it up and running, starting to make a reasonable profit. Take a small salary - to pay for such luxuries as food and heating. As we know, that gets taxed.
Alongside the costs. National Insurance. Business rates. Fees and licences. It is endless.
What’s left after all that? A profit? Surely good news?
Bang. Corporation tax. A big slice gone. After that, we can enjoy a handsome profit. Right?
Nope. Dividend tax. With its brutal thresholds. What slivers you do take get taxed all over again when you want to actually buy something. Obviously.
And the final kick in teeth.
Inheritance tax.
After everything, somehow, you’ve managed to put a reasonable amount of money away. After all that tax, you’ve succeeded in building a financial legacy to pass to your children - your business, and your own savings.
Money you were taxed on the day you earned it, taxed when you saved it, taxed when you invested it, taxed to build your business. It gets taxed one final time. On both your personal savings, and also the value of your company.
Even after death, it continues.
What are we paying all this money for?
Are our schools world-class? Borders secure? Police visible? NHS efficient? Economy thriving? Roads operational?
No. No. No. No. No. No. NOTHING WORKS.
Britain has the highest tax burden in most of our lifetimes, yet the worst services many of us have ever seen. If everything worked perfectly, there could maybe be an argument for such suffocating levels of tax. But it doesn’t, and hasn’t for decades, so there isn’t.
When the taxpayers fail to fund this state monster of inefficiency and unaccountability, what do they do?
QE. Print money. Creating inflation, devaluing our earnings and our savings. Yet one more tax.
The people creating all of this, implementing all of this? £100k plus on the public sector, living in London. Comfortable salary, great pension, no job risk. Clueless about the real world.
Maybe, just maybe, the current approach isn’t working.
We need to urgently cut tax. Shrink government. Reward hard work.
You just can’t tax a nation into prosperity. It never has worked, and it never will work.
LEAVE OUR MONEY ALONE.
#AVCT is now able to walk two horses around the paddock on one set of reins.
One PDC, two warheads.
Most likely Exatecan (which the company knows well) plus another warhead which seeks to disrupt DNA repair. Such as a PARP inhibitor.
PARP inhibitors are a type of targeted therapy commonly used to treat breast cancer and ovarian cancer (and other indications).
They target PARP, or poly (ADP-ribose) polymerase, which is a protein in cells that helps repair damaged DNA. I.e. helping the cancer to reform, grow and disrupt.
This dual-action approach improves efficacy and overcomes resistance mechanisms that limit current treatments, as to survive the tumour would need to resist BOTH drugs simultaneously.
Dual actions ADCs are at the forefront of oncology, @avacta is now playing in that space but with a PDC instead (simpler, far cheaper and easier to produce and more stable).
The IP is new, novel and protected.
As per Trinity Delta: “We believe a new linker, with relevant IP, has been created that, following FAP cleavage, allows the two selected drugs to be released independently in a finely
controlled manner.”
This will have been worked on for a very very long time. Yet this is the first we have heard of it. Every large pharma wants dual-action ADCs.
Here is Avacta sat on a dual-action PDC, yet never before having spoken about it. Not even blurred out in the pipeline. Why?
Easy to forget Avacta has an arsenal of different warheads and different linkers. This is their toolbox at play. There’s as much value in the Avacta team as there is in the IP.
That team likely becomes part of the new FAP division at large pharma when the company is inevitably sold.
Pharma is slow, then quick. The slow bit has been done, we’re now firmly in the action zone: deep into P1b with P2 on the horizon and Exatecan going into clinic in Q1. And a tangible pipeline forming. This is exactly what Pharma wanted to see built. Coughlin has built it - on a shoe string - whilst retaining 100% of everything.
Unicorn drugs don’t make it beyond Phase 2 without being acquired.
ESMO on the weekend, hopefully formally confirming a doubling of the PFS in an indication with no standard of care and - just as importantly for the platform - a clean safety profile. AACR a few days later.
Silent in the bloodstream. Active in the tumour.
#AVCT The foundation of the Avacta value proposition is based on its IP. Lets take a look.
PreCISION was born out of Tufts University by some genius work from William Bachovchin. Make no mistake this guy is an expert on FAP, linkers, PDCs. He designed the linker that is so unique it is only cleaved by FAP.
https://t.co/p3nSNUg1Je
His son David has his own lab at MSK 'The Daniel Bachovchin lab' (our primary trial site where various members of the SAB work, no coincidence we started in the US there)
Eurocrats lecturing Trump about how America conducts its commercial affairs is absolutely priceless. Europe has shut down its nuclear power, swapped out power stations for unreliable windmills, made itself dependent on Russian gas than done everything possible to antagonise Russia.
They then shut down their fertiliser production capacity, drove the chemicals industry overseas, and are now pressing the auto industry to make cars that consumers categorically don't want, pushing the auto industry to the brink of extinction. Now the only way they can meet their own EV targets is to import cheaper EVs from China, which they just put a tariffs on.
Having run down their own industries and infrastructure, they then implement a carbon border tax on cement, iron and steel, aluminum, fertilisers, electricity, and hydrogen - thereby unravelling three decades of trade liberalisation, and in contravention of their own free trade agreements. They then lecture the rest of the world about the "international rules based order". This is the same entity that lectures the world about human rights that has only once rescinded trade preferences on human rights grounds. They will also bleat about democracy while cancelling elections and jailing politicians they don't like.
What Trump is doing right now is not only a corrective to decades of economic mismanagement, it is also a complete repudiation of the Net Zero dogma that has brought European economies to a standstill and driven up costs for everyone. Trump is breaking from the liberal consensus as well as the climate consensus that technocrats have long used to subvert democracy. In calling his latest measures "liberation day" he is not wrong. Most of the West's economic woes, particularly those of Europe, are wholly self-inflicted. Sadly, Europe's liberation is a long way off. For Europe to prosper, the EU must fall.
@TheGreenParty And when they leave the UK, which we’re seeing millionaires do in their 000s, how do you intend to plug the gap? Short sighted approach.
@VP@JDVance ‘s speech at #MunichSecurityConference - one of the best I’ve seen; content, backed by evidence, common sense based and the electoral majority views, and delivered like a true leader for his people. Definite future President, we can only hope for similar in the UK.
A Brit who wants to bring their American, Japanese, Australian, or Canadian spouse to the UK is treated like a genuine criminal by the Home Office.
That's in stark comparison to their warm embrace of male illegal migrants, mainly from alien cultures that share none of our values and hold zero respect for women. Do we want these men in our country? No, we don't. Red carpet for them, a cold bureaucratic wall for Brits and their spouses.
Speak to anybody who has gone through the process - it is brutal, demeaning and actually quite cruel. Couples are kept apart for months, and it costs a fortune. They have to pay £1,035 a year for the NHS, why do illegal migrants get access for free?
Thousands and thousands of pounds are spent. Bureaucratic delays and incompetence are rife, of course.
These are people who want to come, contribute, integrate, build a life and raise their children in our country with their husband or wife.
They should be welcomed - they are trying to do things properly. Illegal migrants are not, and should not be allowed to stay.
Enormously crack down on fraud, naturally - especially on arranged marriages and all of that nonsense. But the constituents I have spoken with are not fraudsters, they just want to see their husbands and wives.
I want pro-family policies. We need to make it easier for Brits to have children, here.
Honestly, the Home Office is such a disgraceful organisation. I truly detest what these snakes have done to this country.
If a British lad marries an American girl and they want to build a life together in the UK, that should be encouraged. You might question their sanity in choosing Britain at the moment, but still...
Hundreds of thousands of legal migrants from Nigeria, Pakistan or wherever else come and bring their dependants - many students! It's a joke. Put brutally, British people should have far more rights than them.
It's our country.
It's all upside down. We're putting thousands of illegal migrants in hotel accommodation, paying for their laundry and food, but a decent taxpaying Brit is treated like a criminal by his or her own Government for having the audacity to marry an Australian or Canadian.
It's insanity.
Our immigration system is disgusting - it benefits ALL the wrong people, and puts Brits at the stinking bottom of the pile.