Chamith Halahakoon

[Chamith Halahakoon @chalahakoon]

Take-home message: depressed individuals experience significant behavioural reward-processing impairments, most prominently on reward bias.

[Chamith Halahakoon @chalahakoon]

More details on the new meta-analysis on behavioural reward processing impairment in #depression by @karelkieslich, @CiaranPsi, @_a_nair, @jonroiser, @GlynLewis9 and I in @JAMAPsych

[JAMA Psychiatry @JAMAPsych]

From @jonroiser, @chalahakoon, @GlynLewis9, and colleagues: new meta-analysis provides robust behavioural evidence for reward processing impairment in #depression, with varying magnitudes across different cognitive sub-components #reward #depression https://t.co/WF2nN30Ja9

[Chamith Halahakoon @chalahakoon]

We looked at whether impaired cognition or anhedonia moderated reward processing impairment. We didn’t find any evidence for this but these analyses were likely underpowered.

[Chamith Halahakoon @chalahakoon]

Overall, depression was associated with small to medium impairments in reward-processing (SMD = 0.345; 95% CI, 0.209-0.480). None of the variance was explained by the medication status of the depressed individuals.

[Chamith Halahakoon @chalahakoon]

We carried out a meta-analysis on behavioural case-control reward processing studies in order to find out whether clinically depressed people have reward-processing impairments https://t.co/trG0mZhmaW