Changya

[Kai Tan Lab @KaiTanLab1]

Excited to share the first spatially resolved multiomics atlas for human bone marrow, published today in @CellCellPress. https://t.co/EVT4qrhiFs. Wonderful collaborations with Ling Qin @LingQin6, Charles Nelson, Martin Carroll, Ivan Maillard, Vinohd Pillai @pillai_vinodh labs!

[Zev Gartner @ZevGartner]

Excited to announce deMULTIplex2 - a powerful new classification algorithm for multiplexed scRNA-seq data from the Gartner lab and @czbiohub, @c3STC, and @UCSF developed by @QinZhu_1 & @Danny__Conrad:
https://t.co/pOlRppyLki

[Changya @Changya1]

@YangDing19 @KaiTanLab1 @ASH_hematology @kathrinbernt @Junjyang Thanks, Yang!

[Kai Tan Lab @KaiTanLab1]

Great presentation @ASH_hematology by another lab member, Changya Chen @Changya1 on characterization of progenitor-like blasts in high risk leukemias! Great collaboration with David Teachey, @kathrinbernt, Sarah Tasiah, @Junjyang labs! #ASH22

[Changya @Changya1]

Thanks for your nice review!

[Erica DePasquale, PhD @EAKDePasquale]

Check out our review of the single-cell multiomics work done by @KaiTanLab1 on KMT2Ar leukemia. It's great to see progress on improving outcomes in pediatric cancers! https://t.co/59YYDJWBHX @vangalenlab @cdktmw @Changya1 @wbaopaul

[Kai Tan Lab @KaiTanLab1]

Happy to share our newest study on KMT2Ar leukemia using single cell multiomics!
https://t.co/TxsJ4p7dfU

[Cancer Discovery @CD_AACR]

Just published #OnlineFirst: Integrative bulk and #singlecell profiling of pre-manufacture T-cell populations reveals factors mediating long-term persistence of #CARTcell therapy. @cdktmw @UPennGCB @ChildrensPhila #immunotherapy
https://t.co/lA5Ct1vRY5

[Changya @Changya1]

@QiQiu8788 Thanks, Qi!

[Changya @Changya1]

So excited to share our preprint about infant leukemia study at single-cell resolution!

[Kai Tan 🇺🇦 @cdktmw]

Excited to share our single-cell multi-omics study of a high-risk subtype of leukemia, as part of the @NCIHTAN. Tremendous effort by multiple labs at @CHOPCancerCntr, @penngenetics, @pennpathlabmed, @childrensmercy, @HopkinsKids.

@bioRxiv viewer https://t.co/493UUQ31PQ

[Changya @Changya1]

@YangDing19 Thanks, Yang!

[Kai Tan 🇺🇦 @cdktmw]

Excited to share our single-cell multi-omics study of a high-risk subtype of leukemia, as part of the @NCIHTAN. Tremendous effort by multiple labs at @CHOPCancerCntr, @penngenetics, @pennpathlabmed, @childrensmercy, @HopkinsKids.

@bioRxiv viewer https://t.co/493UUQ31PQ

[Kai Tan Lab @KaiTanLab1]

Diverse noncoding mutations contribute to deregulation of cis-regulatory landscape in pediatric cancers https://t.co/J6xqAQw3xx

[Kai Tan 🇺🇦 @cdktmw]

Great collaboration with the Speck lab.

[Kai Tan 🇺🇦 @cdktmw]

Excited to share our new method MAPLE for integrating single-cell methylome and transcriptome data based on supervised learning. https://t.co/y7WW5ukHI0

[Speck Lab @LabSpeck]

Our latest puplication is online! The work was a collaboration with @KaiTanLab1 (@cdktmw) with @penggao8, @Changya1, and our graduate student @howell_ED2 leading the work - https://t.co/RB8caPei3y

[Kai Tan Lab @KaiTanLab1]

Very proud of our study. Technically very challenging experiments to do, dealing with rare primary hematopoietic stem cells. Spatial Genome Re-organization between Fetal and Adult Hematopoietic Stem Cells: Cell Reports https://t.co/ZzZPmkYZbw

[Kai Tan 🇺🇦 @cdktmw]

Very excited to share the joint work with the Speck lab to map the transcriptional regulatory circuitry during definitive embryonic hematopoiesis. Kudos to Peng, Changya and Elizabeth from both labs who did the lion's share of the work!
https://t.co/U8Tu0F18OX

[Changya @Changya1]

Transcriptional regulatory network controlling the ontogeny of hematopoietic stem cells https://t.co/VVTIGi8RZA

[Qin Zhu @QinZhu_1]

Very excited to share our new preprint on pre-HSC formation in early development. Feedbacks are welcome! It's a two-years-long effort with Tan Lab (@cdktmw) and Speck Lab to collect and dig into the scRNA and scATAC data and functionally validate our findings!

[Changya @Changya1]

scATAC-pro: a comprehensive workbench for single-cell chromatin accessibility sequencing data https://t.co/I2AvI1vQjs