Jun Yang

Pharmacologist and geneticist through and through

[UChicago Leukemia Program @UChicagoLeuk]

new research featuring @DrWendyStock @CanerSaygin as co-authors looking at BH3 mimetics in T-cell ALL!

https://t.co/YIE7O0dVmN

[Jun Yang @Junjyang]

Look forward to seeing everyone in a few hrs, ASH workshop on functional precision medicine #ASH2025 @ASH_hematology @StJudeResearch @StJude

[Anirban Maitra @Aiims1742]

This is HUGE!
No embargo needed for @AACR publications deposited in PubMed Central - enabling compliance with the NIH public access policy without spending exorbitant open access fees.

[Jun Yang @Junjyang]

New paper alert! Our team published in @NatureComms
on MeiHMM - a hidden Markov model that identifies meiotic nondisjunction error types in chromosomal abnormalities, like Down Syndrome, without parental data! #ComputationalBiology @StJudeResearch
https://t.co/kQCen4lBns

[Jun Yang @Junjyang]

Kudos to @maud_maillard on her new paper in @jclinicalinvest! Our findings indicate NUDT5 is a key regulator of thiopurine metabolism, offering new insights into how cells strike the balance between de novo vs salvage purine synthesis.

[Journal of Clinical Investigation @jclinicalinvest]

Thiopurines for the treatment of cancer or autoimmune disease are limited by their toxicity.

@MaudMaillard @Junjyang @StJudeResearch identify germline NUDT5 variants that affect thiopurine metabolism and cytotoxicity in children with ALL, having implications for individualized thiopurine therapy.

https://t.co/v0UyKOftKl

[Jun Yang @Junjyang]

@LBastian_MD @BloodPortfolio Thanks for writing the editorial piece! A lot more to learn about this drug!@StJudeResearch @StJude

[Jun Yang @Junjyang]

One of my favorite meetings!

[ESH (Haematology) @ESHaematology]

We are a go! #ESHALL2025 started this morning! We are happy to welcome participants in Malahide for the 2,5-day ESH 4th Translational Research Conference on ALL
More information➡ https://t.co/adas9FSZCP
Chairs: @kathrinbernt @CoolsJn @DombretHerve @ullawk
#ESHCONFERENCES #LEUsm

[Jun Yang @Junjyang]

@ADurbinLab @StJudeResearch @MolOnc_StJude @JunQiLab @TheAbraLab Congrats, Adam!

[Rosa Ritunnano @RRitunnano]

Instead of listing my publications, as the year draws to an end, I want to put pressure on the commonplace assumption that productivity must always increase. Good research is disruptive and thinking time is central to high quality scholarship and necessary for disruptive research

[Jun Yang @Junjyang]

#PGRN poster session at John Dutton’s ranch next year? @pgrnhub @ericawoodahl @MinoliPereraPgx

[Jun Yang @Junjyang]

@KaiTanLab1 @NatureCancer @Changya1 @CMullighan Glad to help and to be part of this cool project!

[Jun Yang @Junjyang]

Why is #ALL highly curable in #kids but carries a much worse prognosis in #adults?? Check out our new paper @JCO_ASCO describing genomics of age-related differences in ALL drug sensitivity @StJudeResearch @MDAndersonNews @UChicagoLeuk @NitinJainMD

[St. Jude Research @StJudeResearch]

Researchers identified distinct molecular subtypes of B-ALL that occur in different age groups explaining why cure rates vary between children and adults. The study suggests treatments should be tailored based on underlying molecular groups beyond age.

https://t.co/bLphZdNkJA

[Jun Yang @Junjyang]

@Richardson_S_E Congrats! Thanks for stopping by Carolin’s poster last nite.

[Jun Yang @Junjyang]

@AdeleKFielding @hermione_allen @EHA_Hematology I stopped by your posters last nite, beautiful work!

[Jun Yang @Junjyang]

In beautiful #Madrid for #EHA2024 @EHA_Hematology rooting for Carolin and her poster presentation re inotuzumab resistance in B-ALL

[Jun Yang @Junjyang]

@NitinJainMD @mkonople @EHA_Hematology Thank you @NitinJainMD for picking the nice location and food! #granvia #Madrid

[Jun Yang @Junjyang]

@Rybak_JM Fantastic!!

[Jun Yang @Junjyang]

@KaiTanLab1 @CellCellPress @LingQin6 @pillai_vinodh Really cool stuff! @KaiTanLab1

[Jun Yang @Junjyang]

@AshKishtagari @RaviBha65448036 @JCO_ASCO Very cool study!

[St. Jude Research @StJudeResearch]

Congratulations to Ching-Hon Pui, MD, for receiving the @AACR-@StBalrdricks Foundation Award for Outstanding Achievement in Pediatric Cancer Research. Your pioneering research is lifesaving, and your commitment is inspiring. https://t.co/JNESB5PcJy
#AACR24