Megadalton Solutions

Megadalton Solutions employs proprietary charge detection technology to make mass measurements of biological nanoparticles possible.

[Indiana University @IndianaUniv]

Dr. Martin Jarrold and Dr. David Clemmer of @IUBChemistry at @IUCollege discuss their groundbreaking new technology of charge detection mass spectrometry, or CDMS.

[Megadalton Solutions @chargedetection]

Exciting work profile the interaction of Antibodies with #AAV #GeneTherapy

[Robinson Research Group @CVR_Research]

Our fabulous summer interns have travelled across The Pond from Indiana University to learn lots about native MS! They have been busy working hard in the lab and squeezing in all the touristy bits

@IUBChemistry @KavliOxford @OxfordChemistry

#TeamMassSpec

[C&EN (Chemical & Engineering News) @cenmag]

New technologies including charge-detection mass spectrometry, mass photometry, and nanoelectromechanical systems are allowing researchers to measure the mass of individual molecules, complexes, and particles. Read on to learn how these technologies work: https://t.co/jlakDL3Jy5

[Megadalton Solutions @chargedetection]

Analysis of AAV-Extracted DNA by Charge Detection Mass Spectrometry Reveals Genome Truncations https://t.co/I9H4TyvPZ2

[Megadalton Solutions @chargedetection]

Pleased to showcase the use of CDMS to characterize thermally driven AAV structures. https://t.co/nTU3xN85Ny #AAV #GeneTherapy #bioprocessing

[Megadalton Solutions @chargedetection]

We are excited to be presenting today at #ASGCT2022. Come to Room 204 to see how we use CDMS to directly measure the mass of packaged DNA in AAV.

[The Herald-Times @theheraldtimes]

Two IU chemistry professors found a way to test the effectiveness of pharmaceuticals that could revolutionize the medical field. https://t.co/p51etXWeDA

[IU Innovate Indiana @InnovateIndiana]

An IU faculty startup has reached a deal with a major corporation to use their technology in equipment with applications to the development of new cell- and gene-based therapies. https://t.co/O6HqgwZELL

[BioMassSpec @realBioMassSpec]

Analysis of Recombinant Adenovirus Vectors by Ion Trap Charge Detection Mass Spectrometry: Accurate Molecular Weight Measurements beyond 150 MDa #AC https://t.co/7GWg7Z0e1P

[ACS Analytical Chemistry Journals @an_chem]

Scientists use charge detection mass spectrometry to characterize the megadalton-sized antigens from classical multivalent vaccines directly from commercial formulations.
https://t.co/fjCeFGCWvN

[Megadalton Solutions @chargedetection]

Still time to register for this virtual event on June 24th, in partnership with @Waters and @SelectScience. A lot of great talks on analytical methods and solutions for vaccine and therapeutic development. https://t.co/OrfFhVkEb7”
#vaccines #vaccinedevelopment #virtualevent

[Megadalton Solutions @chargedetection]

#ASGCT21 Join us at 6:45 pm in the Downstream Process of Vector Manufacturing session #aav #genetherapy #adenovirus

[Indiana University Chemistry Department @IUBChemistry]

New work from the Dragnea and M. Jarrold labs shows that co‐assembling brome mosaic virus coat proteins and nucleic acid oligomers generates unstable capsid structures with stoichiometries that differ from the icosahedral virion.

https://t.co/jT9MVbAnSW

[Megadalton Solutions @chargedetection]

Thank you to everyone for making 2020 a success. We look forward to working with you in 2021!

[Megadalton Solutions @chargedetection]

Last chance to register for tomorrow's CDMS webinar! Can't make it? The webinar will be made available on-demand to those who register. https://t.co/u3RknQy50b
#ImmerseLab #WatersInnovation #genetherapy #aav #DNA

[Megadalton Solutions @chargedetection]

Don't forget to sign up for next week's webinar discussing state of the art CDMS technology and applications https://t.co/u3RknQy50b
#ImmerseLab #WatersInnovation #genetherapy #aav #DNA

[Megadalton Solutions @chargedetection]

Megadalton Solutions and Waters innovate together to extend Charge Detection Mass Spectrometry (CDMS) to the cell and gene therapy sectors https://t.co/veNrdVToum
#ImmerseLab #WatersInnovation #genetherapy #aav #iub