Chem 110B

Experiments 💥 exciting science news 🗞PSU research updates 👨‍🔬 and all things Chem 110B! ⚗️Maintained by Phil Bevilacqua

[Chem 110B @chem_110b]

Moderna's RNA vaccine was just approved by the FDA. Use your CHEM110B knowledge to understand how Moderna's vaccine works! https://t.co/bGcWb7ezAU

[Chem 110B @chem_110b]

"1st Patients To Get CRISPR Gene-Editing Treatment Continue To Thrive." One of the first 110B tweets of the semester was on using CRISPR gene editing to treat sickle cell anemia. This morning I heard this promising report. https://t.co/tLbVHhTveV

[Chem 110B @chem_110b]

First mRNA vaccine ever approved, from Pfizer. Look for Moderna's mRNA vaccine to be approved very soon too! Attacking an RNA virus with mRNA. Here's to a return to normality in 2021! https://t.co/7SjU3yMf9C

[Chem 110B @chem_110b]

Wonderful message from CHEM110B students! Thanks back to you for a great semester!

[Chem 110B @chem_110b]

No doubt about it, thermite is an exothermic reaction! Thank you Bob for the thermite stories and Philip for the videography.

[Chem 110B @chem_110b]

Read about Professor Andrew Read's latest breakthrough: 'Anti-antibiotic' allows for use of antibiotics without driving resistance | Penn State University https://t.co/97V44TPOE0

[Chem 110B @chem_110b]

Reduce CO2 emissions from burning fossil fuels and create jobs. Penn State University endorses climate change letter to world leaders | via @penn_state https://t.co/UOkfnh8mhY

[Chem 110B @chem_110b]

Well said Royal Society of Chemistry! My CHEM110B class will appreciate this clear explanation of RNA vaccines for COVID-19.

[Chem 110B @chem_110b]

Google's DeepMind program reports today using artificial intelligence (AI) to make gigantic leaps in solving protein structures! The 3 proteins in our COVID-19 take home were solved experimentally, but in the future a computer might do it much faster! https://t.co/TkQOHNwnJi

[Chem 110B @chem_110b]

https://t.co/MgBHYxZFwO

[Chem 110B @chem_110b]

Topic for the week ahead. Antibiotic-resistant Germs: New Threats https://t.co/Xt02vdrGjZ

[Chem 110B @chem_110b]

Here is a personal story to go with the preceding antisense oligo (ASO) Spinraza tweet.
https://t.co/bwiyzhWfPq

[Chem 110B @chem_110b]

Antisense Oligonucleotides (ASOs) have come into their own in the last few years. Read this story of a treatment for spinal muscular atrophy (SMA) using the ASO nusinersen (Spinraza) developed by my colleague Adrian Krainer.
https://t.co/MzSDbXoIz6

[Chem 110B @chem_110b]

Meet Dr. Melissa Moore. She is a star RNA researcher. A few years ago she left UMass Med and HHMI to be Chief Scientific Officer at Moderna. Now she is helping to save the world with a 95% effective RNA vaccine! Thank you Melissa! https://t.co/Rb90pEbKLI

[Chem 110B @chem_110b]

Sharing an outstanding research publication from CHEM110B instructor Dr. Zhang. His lab makes and studies probes to understand neurodegenerative diseases.

[Xin Zhang @kfzhangxin]

Congratulations to Songtao Ye!!! His first work at Penn State revealed an interesting mechanism to control viscosity sensitivity of molecular rotor-based fluorophores. @psu_chemistry

[Chem 110B @chem_110b]

Meet Percy Lavon Julian who was a pioneer in synthesis of drugs, done during an era in which segregationist laws limited Black Americans’ access to higher education. He is known for his 11-step synthesis of physostigmine, an alkaloid that can be used to treat glaucoma.

[Chem 110B @chem_110b]

Today we discussed specificity challenges of drugging the human kinome. Recent studies have identified over 175,000 substrates of 385 kinases, which sheds further light on the challenges of kinase drug development.
https://t.co/fhDuJY0plG

[Chem 110B @chem_110b]

Yesterday, we studied stoichiometry in simple combustion reactions, but stoichiometry is essential in biochemistry too. Here is a chromatin-enzyme complex from the Tan Lab at Penn State BMMB. Histones, DNA, and enzymes are in fixed stoichiometric ratios.https://t.co/MM7xGhWx7R

[Chem 110B @chem_110b]

Incomplete combustion of fossil fuels, from poor availability of O2, leads to soot which can lead to cancer.
https://t.co/eUg4iTvrQo

[Chem 110B @chem_110b]

Volatile Organic Compounds (VOCs) have low IMFs and low solubility in water, allowing them to escape to the atmosphere. Plants use VOCs to "talk" to one another. Image: VOC-network of interactions between species. Yellow is the most active VOC network.
https://t.co/z1MKhzWuKr