Newly posted video - a reaction to Extractions&Ire's video on converting adipic acid to cyclopentanone. ~31 min #organicchemistry
https://t.co/H2UQCfdndb
New video on the FDA approval of TRYVIO (aprocitentan), a treatment for hypertension. NDA sponsored by @Idorsia. Overview of med chem properties. 10 min. #medchem#drugdiscovery https://t.co/i5xho4hgta
New video on nivasorexant, an orally available selective orexin-1 receptor antagonist discovered by @Idorsia. Video based on recent J Med Chem Drug Annotation article. 13 min. #medchem@ACSBioMed#drugdiscovery https://t.co/frdN9mi8RH
New video on the FDA approval of REZDIFFRA (resmetirom), a treatment for NASH/MASH. NDA sponsored by @MadrigalPharma. Overview of med chem properties. 11 min. #medchem#drugdiscovery https://t.co/SAZgQVeWKG
New playlist about lead discovery & optimization in drug discovery. Topics include screening, target engagement, SAR studies, & isosteres/bioisosteres. 21 videos, ~90 min total. #medchem#drugdiscovery https://t.co/lm2AhGVDkF
New video on the FDA approval of EXBLIFEP (cefepime & enmetazobactam), an antibacterial for complicated UTIs. NDA sponsored by Allecra. Overview of med chem properties. 11 min. #medchem#drugdiscovery https://t.co/I15scWYuR7
New playlist about preclinical/nonclinical safety in drug discovery. Topics include sources of toxicity, hERG inhibition, & safe starting dose estimates. 21 videos, ~90 min total. #medchem#drugdiscovery https://t.co/wGNqllaaSS
New video on the discovery of KIN-3248, a pan-FGFR inhibitor for treatment of certain cancers. Video based on recent J Med Chem Drug Annotation article. 11 min. #medchem@ACSBioMed#drugdiscovery https://t.co/6uQ6mtgQrK
New playlist about ADME & PK in drug discovery - from membrane permeability to PK parameters & PK/PD models with some sample calculations. 23 videos, ~120 min total. #medchem#drugdiscovery https://t.co/dYwxKErVLT
New video on the discovery of JTE-151, a RORg inhibitor for certain autoimmune diseases. Video based on recent J Med Chem Drug Annotation article. 13 min. #medchem@ACSBioMed#drugdiscovery https://t.co/1Wrxbof1Vb
New playlist about measuring biological activity for compounds in drug discovery and interpreting activity data. 21 videos, ~100 min total. #medchem#drugdiscovery https://t.co/qFVnvPlE7k
New playlist with a broad treatment of some business, legal, & regulatory aspects of the pharmaceutical industry. 21 videos, ~80 min total. #medchem#drugdiscovery https://t.co/NbCzMFfxN0
New video on the FDA approval of gepirone (EXXUA), an oral 5HT1A partial agonist for major depressive disorder. NDA sponsored by Fabre-Kramer. Overview of med chem properties. 9 min. #medchem#drugdiscovery
New video on the FDA approval of momelotinib (OJJAARA), an oral JAK inhibitor for myelofibrosis treatment. NDA sponsored by @GSK. Overview of med chem properties. 11 min. #medchem#drugdiscovery https://t.co/qa2KE99S7c
New video on the FDA approval of palovarotene (SOHONOS), an oral RAR-gamma agonist for rare bone tissue disorders. NDA sponsored by @IpsenGroup. Overview of med chem properties. 11 min. #medchem#drugdiscovery https://t.co/SlZrsDnHEz