Che-Min Lee

UBC BC Cancer PhD Candidate • fibroblast and TME nerd • occasional oboist

[The Stromal Network @StromalNetwork]

❗📢 We’re excited to invite Stromal Biologists to the Stromal Network's Journal Club 2025!
❗📆 We are kicking off 2025, with out first Journal Club meeting that with take place on Monday, February 17th, 2025 at 9am PST - 5pm GMT - 7pm EET.
Details -> https://t.co/zHIwAQik67

[Che-Min Lee @CheMinLee1]

@nikita_telkar @erikacule Ahahahaha was thinking of you 😂🫰🏼

[Christine Mayr @Mayr_Christine]

New preprint from us!

mRNAs act as chaperones for IDRs.

mRNAs often bind to IDRs. This changes their conformational ensembles to drive protein complex assembly, and controls protein activity.

Thank you @VickyLuo0223!

https://t.co/0LeTA2bjXv

[Herbert B Schiller @SchillerLab]

[1/7] How do fibroblasts sense the mechanical properties of their tissue microenvironment?

Check out our new paper on @biorxivpreprint:

https://t.co/KlfJCjE5Md

#mechanobiology #systemsbiology #phosphoproteomics #fibrosis
@HelmholtzMunich @labs_mann @LungHealthMUC @dzlacademy

[Lisa deCotret @LdeCotret]

Excited to share the @KevinBennewith’s lab most recent work in @FrontiersIn! We provide a new perspective on performing ex vivo brain slice invasion assays. https://t.co/QWaBNSES7z

[Che-Min Lee @CheMinLee1]

@LdeCotret @KevinBennewith @FrontiersIn Woohooo congrats Lisa!!! 🎉🎉

[Ruth Shouval @shouval]

A cell circuit approach to dissect fibroblast-macrophage interactions in the tumor microenvironment https://t.co/Gkrrl0QMYh

[Mike Murphy @mcwm]

get your flu shot
https://t.co/57eGMI5wp9

[Che-Min Lee @CheMinLee1]

@nikita_telkar @UBC @Robinson_Lab @TheLamLab Congrats Nikita!!! Super well deserved you star! 🌟🎉

[Anirban Maitra @Aiims1742]

Pan-cancer single-cell analysis reveals the heterogeneity and plasticity of cancer-associated fibroblasts in the tumor microenvironment
https://t.co/244zBeiofg
A dozen publicly available scRNA seq datasets were collated for this study. CAF Browser at:
https://t.co/aFKR7twYvm

[Anirban Maitra @Aiims1742]

In @Cancer_Cell
Multiomic analysis reveals conservation of cancer-associated fibroblast phenotypes across species and tissue of origin
https://t.co/A0Q9Y4R5to
Three functional categories (“superclusters”) of CAFs across solid tumors (including #PancreaticCancer).

[Ivan Zanoni @Lo_Zanzi]

#EveryCell_is_AnImmuneCell!! Müller Turley &co show ⁦@Nature⁩ that #TGFb drives the expansion of a population of #tumor-associated myofibroblasts that suppresses #CD8Tcell protective responses, identifying a new therapeutic target against tumors! https://t.co/gjn15kaXay

[Che-Min Lee @CheMinLee1]

@melese_mi @ninan_abraham1 Woohoo! Congrats Dr. Melese!!! 🎉

[Che-Min Lee @CheMinLee1]

@nikita_telkar @Backmanland I love Fredrick Backman’s books! Super glad I found another fan 😁

[Mushtaq Bilal, PhD @MushtaqBilalPhD]

How to MOVE your Mendeley library to Zotero:

A step-by-step guide with visuals 🧵

Why move, you ask?

Elsevier is SHUTTING DOWN Mendeley Desktop app on Sept. 1, 2022 😱

[Buitengebieden @buitengebieden]

A smile for your timeline.. 😊

🎥 IG: babydollsheepuk https://t.co/aUIlUl1e5b

[Hank Green @hankgreen]

IT'S HERE!! IT'S NOW!! IT'S HAPPENING, AND YOU CAN UNDERSTAND IT!!! https://t.co/zHR9pDT7il

[Eugenio F. Fornasiero @euforna]

Expansion microscopy at one nanometer resolution #ONE_Microscopy, a possible game changer? Great work done by an amazing team! https://t.co/GaPLahBmG2

[Jeff Lotthammer @jefflotthammer]

AlphaFold, ColabFold, ESMFold, OmegaFold? Well … allow me to introduce you to DALL-E-Fold.

Unlike other recent methods that use protein sequence to predict structure, DALL-E-fold is able to predict a structure* of a protein with just a name and a dream!

*results may vary

[George Caputa @curiousdrgeorge]

How do oocytes remain viable over a lifetime?

An exciting study by @LabBoke in @nature finds that oocytes have reduced expression of mitoETC complex I to limit ROS-associated damage and promote cellular longevity.

OA: https://t.co/jx94TlWBcT
https://t.co/n3fc53E0x8