BökeLab

Oocyte Biology and Cellular Dormancy Lab in @CRGenomica, Barcelona, led by Elvan Böke. Joint lab account; tweets by Elvan are signed EB.

[BökeLab @LabBoke]

What does an ovary actually look like as it ages—one oocyte at a time?
We mapped >85,000 oocytes in >100 intact mouse ovaries, in 3D, across the reproductive lifespan. And the ovary turned out to be much more organized than we expected. 🧵 1/5 https://t.co/BUeZBI3vJA

[Biomedical Picture of the Day BPoD @BPoD_s]

The ovary actively 'counts' its eggs, preparing the same proportion for ovulation, at different stages of life

📹 Arturo D’Angelo et al @LabBoke @CRGenomica in @NatureAging
➡️ https://t.co/d110WNsowe

[Discover Magazine @DiscoverMag]

Learn more about the first-ever 3D map of an ovary and how it could reshape our understanding of fertility, menopause, and women's reproductive health. https://t.co/pBqnZRvWzg

[Catalunya Color @CatalunyaColor]

La Barceloneta, el 1973.
📷Color original

[BIST-Barcelona Institute of Science and Technology @_BIST]

🗺️ First 3D map of ovary throughout reproductive lifespan reveals it counts its own eggs

A new study published in @NatureAging by @CRGenomica researchers challenges the idea that ovaries are simply passive egg reservoirs

@LabBoke #BISTCommunity

👉 https://t.co/uw0oBskosY

[Gabriele Zaffagnini @zaffagg3]

Happy Sunday with another issue of #cebooc!
This weeks @LabBoke shows the dynamics of follicle depletion with age using whole 3D imaging of intact mouse ovaries: https://t.co/uXYkDdC6gT

Read the full issue for more exciting papers: https://t.co/T7ugUN75fN

subscribe here: https://t.co/zLshZzoAO9

Thanks @Bims_BiomedNews for preselecting!

[BökeLab @LabBoke]

And I somehow ended up the only woman on the author list of a paper about ovaries. 😅
Very proud of this team and what we built together. 5/5

[BökeLab @LabBoke]

What does an ovary actually look like as it ages—one oocyte at a time?
We mapped >85,000 oocytes in >100 intact mouse ovaries, in 3D, across the reproductive lifespan. And the ovary turned out to be much more organized than we expected. 🧵 1/5 https://t.co/BUeZBI3vJA

[BökeLab @LabBoke]

This work took a village and several disciplines: Led by the fantastic Arturo D’Angelo, with Daniel Franco-Barranco, Marco Musy, @jmduranse , James Sharpe, @nstroustrup1 & Ignacio Arganda-Carreras bringing together imaging, AI, statistics and mathematical modelling. 4/5

[ShorterLab @ShorterLab]

Exclusive: Death of girl in Chinese gene-editing trial was never made public | Science | AAAS https://t.co/VLbGGaxCjA

[BökeLab @LabBoke]

Keeping oocytes alive for decades is a massive challenge, but so is earning a PhD with the highest honors! 👏

Massive (belated!) congratulations to our PhD student, Dr. Devesh Bahety (@devbahety) for defending his thesis and receiving an excellent cum laude! 🥳🏆

@CRGenomica

[Fundación Banco Sabadell @FBSabadell]

Desde la Fundación Banco Sabadell felicitamos a los dos premiados, @marcguellc y @garciadearquer, y agradecemos a todas las personas que nos han acompañado en esta nueva edición de los #PremiosBiomédicaCiencias.

Una cita anual que reúne a la comunidad científica para reconocer la excelencia científica y su potencial de impacto social.

#LaCulturadelTalento #Investigación

[BökeLab @LabBoke]

Exactly my thoughts re the "unbiased" QED 1% list- this analysis puts it on firm footing. One thing not captured here is the prominence of well-established authors; that's what triggered me whether QED was really ranking the science OR signals assoc'd w/ scientific prominence- EB

[Ran Blekhman @blekhman]

I wanted to like QED's new 1% preprint ranking. But the more I looked at the data, the more uncomfortable it made me. Here is my full peer review:

https://t.co/c8a0B344Od

[Physics of Life Dresden @PoLDresden]

🏆 Introducing the inaugural Suzanne Eaton Awards for Physics of Life!

👨‍🔬We're thrilled to announce the 2026 recipients: L. Mahadevan @Harvard and Anna Erzberger @embl who will give their award lectures on 20. November.

➡️Read our announcement here: https://t.co/2NeUinqmOm

[Mizushima Lab (UTokyo) @MizLabUT]

Our new paper is out in @ScienceMagazine! We developed mice with reversible control of autophagy, and showed that restoring this pathway after its suppression reverses neuronal abnormalities and brain dysfunction, demonstrating the resilience of neurons. https://t.co/kegmU08mcY

[BökeLab @LabBoke]

@qedScience @IMPvienna @viennabiocenter Out of curiosity - how sure are you that the score was assigned "blind"to author, institution etc? Have you figured explainable AI for QED? - EB

[Joffrey pelletier @Joffreypelleti1]

📢 Open Postdoctoral Position!
Interested in cellular plasticity and translational control? Don't miss this opportunity!

We are looking for a motivated postdoctoral researcher to join our team and contribute to cutting-edge research.

🔗 For more information👇

[Michael Baym @baym]

“Towards”

[Arjun Raj @arjunrajlab]

Can someone start a journal called “Cell Atlases” so that the rest of the journals can go back to publishing interesting things?