Nature Aging

Nature Aging is a thematic Nature journal that serves the broad aging research community. Follows & RT ≠ endorsements.

[Nature Aging @NatureAging]

🗞️Our October issue is live!✨Read about lipid remodelling and lifespan regulation; how age-related T-cell accumulation drives myelopoiesis; senescent B-cells in rheumatoid arthritis risk; exercise-derived vesicles promote cartilage health & much more! https://t.co/V7CsXx66HL

[Nature Aging @NatureAging]

📎 And read the News & Views written by Shuai Ma & Jing Qu https://t.co/1mu6T9tykO

[Nature Aging @NatureAging]

Online now!✨@kezhang2021 @xingjchen7 @f_monticolo @Salvato88775199 et al pair Raman imaging with spatial and single cell transcriptomics in aging and repair, and identify a lipid-linked Raman signature of p21+ cells @JianShuLab https://t.co/UXNAnUU1tY

[Nature Aging @NatureAging]

📎And now read the associated Research Briefing: https://t.co/riDIOr9hWp

[Nature Aging @NatureAging]

Online now! @EnriqueGab, @gsotoheredero et al identify an accumulation of cytotoxic CD4+ T cells producing CCL5 in the bone marrow during aging, linked to age-associated myelopoiesis. Blocking this axis improves healthspan in aged mice @MMittelbrunn https://t.co/kEvxzMnk14

[Nature Aging @NatureAging]

🗞️Our September issue is live!✨Read about trained immunity driving inflammaging; senomorphic potential of CDK4/6 inhibitors; muscle grafts mimic exercise benefits; mtDNA drives ovarian inflammation; aging diseases dominate global health & much more!
https://t.co/t0rt8bbXoX

[Nature Aging @NatureAging]

Could molecular diagnostics advance our understanding of Alzheimer's? Applications are now open for the 2026 MDx Impact Grants, supporting research on molecular markers of neurodegeneration using Seegene's high-multiplex PCR technology. https://t.co/mxgV3ZEef7

[Nature Aging @NatureAging]

Online now! Cerrato et al propose a consensus roadmap towards precision senescence medicine, emerging from the SENESCENCE2030 meeting in Coimbra, Portugal earlier this year @marc_dema https://t.co/pgMKLOYtrp

[Nature Aging @NatureAging]

Online now!✨@anamikaa_yadav et al develop a framework to quantify tissue structural aging, without training on chronological age, using GTEx histology image data, finding distinct and coordinated organ aging trajectories @Sanjusinha7 @sbpdiscovery https://t.co/Ih0gcAkNlo

[Nature Aging @NatureAging]

📎And now read the associated Research Briefing https://t.co/ynMGJuQe8R

[Nature Aging @NatureAging]

Online now!✨Martinez, Morandini et al identify a role for cGAS in chromatin organization: cGAS knockout mice show compromised heterochromatin organization, LINE1 depression, inflammation, and shortened lifespan https://t.co/A4Rmf4v61I

[Nature Aging @NatureAging]

@CSIC @CBM_CSIC_UAM

[Nature Aging @NatureAging]

Online now! @EnriqueGab, @gsotoheredero et al identify an accumulation of cytotoxic CD4+ T cells producing CCL5 in the bone marrow during aging, linked to age-associated myelopoiesis. Blocking this axis improves healthspan in aged mice @MMittelbrunn https://t.co/kEvxzMnk14

[Nature Aging @NatureAging]

Online now! In a World View, primary care physician Dean Ariel reflects on how conversations about geroscience unfold in his clinic, amidst the evolving landscape of public engagement with aging research https://t.co/84GOU0NpHI

[Nature Aging @NatureAging]

Online now!✨Martinez, Morandini et al identify a role for cGAS in chromatin organization: cGAS knockout mice show compromised heterochromatin organization, LINE1 depression, inflammation, and shortened lifespan https://t.co/A4Rmf4v61I

[Nature Aging @NatureAging]

📎Liqin Wang & Rene Bernards discuss both studies in a News & Views https://t.co/6I7z085nB4

[Nature Aging @NatureAging]

Online now!✨Wang et al report a role for CDK4/6 in regulating not only cell cycle progression but also the SASP, via retinoic acid signaling and NFkB. Targeting this pathway reduces inflammation and improves function in aged mice @Marc_dema https://t.co/e5PnvbjcK8

[Nature Aging @NatureAging]

✨Rajesh et al also report an unexpected role for the cell cycle regulators cyclin D1 – CDK6, as regulators of SASP via DNA damage and cGAS-STING. Blocking this pathway with palbociclib improves motor function and frailty in aged mice @AdamsBioAging https://t.co/z5T4tMEiat

[Nature Aging @NatureAging]

Register now for Reframing Precision Medicine: Innovation to Implementation, a flagship Nature Conference in London from 13–15 Oct 2026. Learn more at https://t.co/gbTTzEUFbu

[Nature Aging @NatureAging]

🗞️Our August issue is live!✨Read about fructose drives metastasis from senescent ovarian cancer cells; dietary valine restriction improves mouse healthspan, 5 blood proteins predict MASLD up to 16 years before onset & much more
https://t.co/YXaKPgcGPV

[Nature Aging @NatureAging]

📎Now read the associated News & Views from Maz Divangahi & Katherine King https://t.co/5JfoexMXA6

[Nature Aging @NatureAging]

Online now!✨Mu, Barthez, Feng, Chen, Wang et al report that trained immunity links hematopoietic stem cell aging to age-associated inflammation https://t.co/lvuDNinhT8

[Nature Aging @NatureAging]

Online now!✨Cole et al identify fructose as a component of the therapy-induced SASP in senescent ovarian cancer cells and show that it reprograms cancer cells in paracrine, promoting detachment and metastasis @airdlab https://t.co/nkUTtJnEWX