Evan Chiefer

Student at the University of Pittsburgh majoring in Biochemistry. Pursuing virology to advance our understanding of pathogens and ways to eliminate them.🦠🔬

[Evan Chiefer @ChieferEvan]

I'd also like to add to this that there arises a grave issue when those who are pandering to a specific demographic warp their beliefs in the name of influence, power or financial gain. Yet again it is analogous to the Purdue incident. Scientists do their research, the research gets debunked, the companies or politicians then ignore the new research (which is a flaw of the scientific method) if it vaguely disagrees with the agenda or drug they are pushing. We've seen this with vaccines, specifically the MMR scandal regarding autism in vaccines which was found to have contained fabricated statistics, was done on an incredibly small cherry picked sample size and whose results have not been reproducible to this day (though many still actively try to prove this association). The amount of roadblocks and cross checking within scientific research is fierce and in all honesty those in the field are pushed equally hard to disprove past findings as they are to pursue new ones. The whole system is built on a consistent fact-checking basis and the entire system HAS to abide by this scientific methodology. When it was first theorized that H. Pylori was the causative agent of stomach ulcers the widely held scientific belief was that bacteria could not even survive in the pH of stomach acid, yet the theory was proven true when time and time again scientists tried to disprove the H. Pylori hypothesis and failed to disprove it time and time again. This research, which yet again was published, was in part met with major backlash by insurance companies, politicians, and pharmaceutical corporations since the existing treatment protocols were financially lucrative for the medical and pharmaceutical industries. Pharmaceutical companies sold billions of dollars in antacid and acid-suppressing drugs, like Tagamet, which treated the symptoms but not the root cause. Insurance companies profited off of partial gastrectomies to treat ulcers, a profitable procedure that would be rendered unnecessary if a simple antibiotic cure were available. Therapists and psychiatric companies, as well as insurance companies profited off of stress treatments since it was said "stress" caused stomach ulcers. In order to finally settle the science, Barry Marshall literally drank a culture of H. pylori to prove it would cause gastritis, which it did, and then treated himself with antibiotics.
Conclusions within the scientific community are not reached through one study or through one individual, they are CONSTANTLY belittled, challenged and tested. The science becomes settled whenever every possible attempt to disprove a finding cannot do so and no amount of narrative twisting by those who are not within scientific research communities stands a chance at distorting the results of the research. It's so frustrating how researchers simply do their jobs and then get their findings twisted out the mouths of corrupt CEOs and politicians and the public backlash focuses on the scientists themselves. Experts are experts for a reason, and if anyone in the scientific community does take bribes or unknowingly prescribe dangerous things it's doctors, who are trained to look at research but more so are constantly briefed by pharma companies on drugs they're selling who typically don't look any further into the matter than the statistics displayed to them by the seller of the drug themselves. Doctors play NO PART in actually DOING the research or scientific discovery and are simply trained on what discovered things are available to treat their patients. Research is a whole different field of medical science. Researchers cannot treat patients but can get data from treated patients and doctors cannot do research besides helping administer clinical trials. Modern science is so fucked because it's not the science that's at fault it's the people who oversee the science and the people who profit from it.

[Evan Chiefer @ChieferEvan]

That's why there are conflict of interest statements in research papers and is also why we laid the legislative hammer down on pharma companies after what Purdue did- Purdue Pharma intentionally misused a single-paragraph letter published in a 1980 edition of the New England Journal of Medicine. The letter, from authors Hershel Jick and Jane Porter, observed a low rate of addiction in a group of closely monitored hospitalized patients who were taking opioids. Purdue's marketing materials then twisted this limited finding into the blanket claim that the risk of addiction was "much less than 1%" for all prescription opioid patients, including those with chronic pain. The company was aware of internal research by Lawrence Robbins et al that found addictive behavior in 8% to 13% of OxyContin patients. Rather than pursuing the concerning nature of these findings, Purdue pushed the ≤1% narrative using the flawed Jick and Porter study; internal documents from 1996 revealed Purdue knew about widespread abuse of OxyContin, the company did nothing to address the issue. The issue yet again, was never the scientists, the scientists knew about the 8-13% statistic. The issue once again was the business aspect, the company and its representatives- who were trained to tell doctors that signs of addiction, such as requests for early refills, were actually signs that the patient's pain was not being treated effectively. They were taught about the fabricated concept of "pseudoaddiction" to encourage doctors to prescribe even higher doses. Purdue also aggressively targeted doctors with meals and gifts, while tracking their prescription habits (which is now illegal). The company often targeted high-prescribing physicians, even those with known histories of improper prescribing (which is now illegal but still occurs) incentivized sales representatives with high commission and fired those who questioned their narrative. They also sent representatives to areas "with high rates of pain" although these yet again were just vulnerable communities like the poor (miners, laborers, etc) the sick or the old. The sales representatives for the most part were doing their job marketing a drug they had been convinced was a solution. Those who held the fault were the higher ups in the company who silenced published studies disagreeing with their claims and brainwashed their sales representatives. The Purdue Scandal is absolutely perfect at capturing what's wrong with modern science and it is NOT the scientists, who were doing valid research and publishing papers warning about Oxycontin. The 1% statistic wasn't even funded by Purdue, it was a small unreliable study done with a tiny sample size on an observed population that was warped by a company. The writer of the "Letter to the Editor" actually ended up suing the company if I recall and deeply regretted publishing it in a paper. Yet again, he was simply doing research, every scientist was doing research and publishing their findings. The key aspect is that science builds and concept proofs nearly constantly and when that 1% statistic was debunked it was no longer in the hands of the scientists, they'd done their job, it was in the hands of politicians, who were lobbied by Purdue. Research is always accurate, interpretations and spins of the research are not. You cannot blame anything within STEM for the actions of corrupt politicians or greedy multinational pharma corporations. There are an insane amount of stage III clinical trials which fail and it's partly due to the much, much heavier restrictions put onto scientific research after the Purdue incident and subsequent opioid crisis. If anything due to that science is more transparent than ever, people just will be people and trust "experts" without medical degrees who say what they will say about data that they cannot even begin to comprehend. Truth is truth coming from an unbiased expert, no one going to law or business can be an expert in medicine.

[Evan Chiefer @ChieferEvan]

Intriguing

[Evan Chiefer @ChieferEvan]

@rushtropicalwx https://t.co/r40AI5jFGZ

[Evan Chiefer @ChieferEvan]

Well in terms of a collapse of the AMOC very drastic things but also not what I think we'll see in the near term (speaking decades); with that being said, AMOC collapse is a feedback loop so a destabilized Gulf stream would transfer much less heat to the poles, which would in turn lead to a loop wherein less cold water is recirculated south into the Atlantic gyre to be reheated and transferred back north, which would result in colder water stagnating in the Arctic and warmer water stagnating near the equator. It would also result in the formation of much more ice near the poles, since colder water sinks faster and warmer water near the surface would be subject to increased cooling from the Arctic environments. Assuming this trend, you'd see a much colder environment in northern latitudes and tropical rain belts would be pushed further South (since less water would be circulated resulting in simultaneous north Atlantic cooling and south Atlantic heating). It would be catastrophic for oceanic environments and ecosystems and would likely lead to unpredictable and extreme weather patterns, especially in Northern Europe while the southern shift of tropical rain belts would be catastrophic for the Amazon rainforest and other established equatorial jungles.

[Evan Chiefer @ChieferEvan]

Goated Saturday soundings for the Ohio Valley. Are we back?

[Evan Chiefer @ChieferEvan]

#pawx rise up. Charge your cameras. The Ohio Valley is developing nuclear weapons.

[Hunter Biden @HunterBiden]

WTF timeline are we on. Someone called me the MAGA whisperer and I’ll gladly take the title. Left, right, D or R we all want the same things. We’re being divided on purpose by the Epstein Elite Oligarch class because as long as we’re at each other’s throats, they get fat and rich off of our misery. The second we figure out we agree on more than we disagree, they’re done. Love your neighbor. Be yourself. Radical honesty. No fucks given, no fucks taken. Everything else is just noise. (But still fuck Jake “Brick Tamland” Tapper on any time line)

[maybe: k*rk @a_dose_of_wx]

A data center would make a great damage indicator for a violent tornado

[Evan Chiefer @ChieferEvan]

Highly anomalous temperatures in the gyres of the Gulf stream are the result of a destabilizing Atlantic Overturning Circulation. It's a canary in a coal mine because it has both anomalous highs and lows within the circulation which increased intermixing of hot and cold water off New England prior to the northern extent of the Gulf stream. At least that's what I picked up on.

[Evan Chiefer @ChieferEvan]

@stainless_squid On God bro?

[Evan Chiefer @ChieferEvan]

@Tommy2legs @HunterBiden @theliamnissan Word?

[Evan Chiefer @ChieferEvan]

@HunterBiden @theliamnissan Bro came back to X to set up his presence in the ring 😂

[Hunter Biden @HunterBiden]

@theliamnissan It would be my honor.

[Forbes @Forbes]

Hunter Biden, the youngest son of former President Joe Biden, has stepped back into the public eye with a series of attention-grabbing social media posts.
Read more: https://t.co/9D0YXSROBg
Photo: Samuel Corum via Getty Images

[Hunter Biden @HunterBiden]

@JaulaDePerreo How about “Let’s take another crack with a Biden.” Needs work but the possibilities are endless.

[Hunter Biden @HunterBiden]

@Kenn321705 I’ve never stolen an erection in my life.

[Evan Chiefer @ChieferEvan]

Carrington Municipal Airport has fallen.

[Evan Chiefer @ChieferEvan]

Absolutely pristine hail producer

[Tanner Charles 🌪 @TannerChasing]

Things that put a knot in your stomach. Guessing this car wasn't a chaser - they drove right into this tornado. Not sure what happened to them.

Looking west at the intersection of 291st st and 469th ave - 9:01pm

#sdwx