Simone Cimminelli

Running my holding company. Believe entrepreneurship is a force for good.

[Simone Cimminelli @Cimminelli]

In tech we went from Steve Jobs to no jobs thanks to ai

[Avi Roy @agingroy]

Eli Lilly released retatrutide Phase 3 data yesterday. 28% weight loss in 80 weeks. The most powerful obesity drug that’s ever been tested.

And today the cancer signal drops.

12,112 patients. Seven tumor types. GLP-1 users had half the lung cancer metastasis rate (10% vs 22%). Breast cancer: 43% cut. Colon cancer five-year mortality in a separate study: 15.5% vs 37.1%.

Cancer joins a list that already includes heart disease (SELECT, 20% MACE reduction), kidney failure (FLOW, 24% slower decline), sleep apnea (SURMOUNT-OSA, FDA-approved), addiction (BMJ, 600K veterans, 18-25% reduction across substances), and liver disease (86% fat clearance).

Tumors express GLP-1 receptors. Activate them and NF-kB drops, apoptosis rises. The drug isn’t just shrinking fat. It’s talking directly to the cancer.

One drug class. Designed for blood sugar. The biology keeps finding uses the designers didn’t predict.

[Simone Cimminelli @Cimminelli]

@dividendology The trade off is an illusion

[Simone Cimminelli @Cimminelli]

@JesseTinsley https://t.co/zT0qQLiomr

[Simone Cimminelli @Cimminelli]

@mewwts Yes and I am not going back. To me alcohol was primarily a great social lubricant. I have morphed in a more self confident men over the decades. I still enjoy going out very much and I am happy to do it regularly even alcohol free. The day after I feel fresher.

[Simone Cimminelli @Cimminelli]

My crm syncs emails, calendar, tasks, deals and WhatsApp. It’s so good that I leave my Pa taking care of it. Only give her input in a 40’ early morning meeting. She is not allowed to reach out to me during the day. She send me a recap acting as agenda every evening. Never been so productive and free to focus to my actual work

[Simone Cimminelli @Cimminelli]

@Jason i'm in

[Simone Cimminelli @Cimminelli]

@boringmarketer 💯

[Simone Cimminelli @Cimminelli]

@euronationalizt Book me in

[Simone Cimminelli @Cimminelli]

Opus 4.6 is now retarded

[Simone Cimminelli @Cimminelli]

X is now a 💩 TikTok clone

[Simone Cimminelli @Cimminelli]

@PeterJ_Walker Likely the f.o. will not have to read all the follow ups, also on their side will use an agent. :)

[Simone Cimminelli @Cimminelli]

@Rikardoplav how much?

[Thomas Massie @RepThomasMassie]

Congratulations AG Blanche. Now you have 30 days to release the rest of the files before becoming criminally liable for failure to comply with the Epstein Files Transparency Act.

[AnthonyAndrews @anthon7yandrews]

“Mr. Trump and Mr. Epstein knew that I was 13 years old.”
Given the latest news, this deserves another look by everyone. It’s only two pages. Also please share widely on all platforms. Save the screenshots to your phone and share on your own platforms. We need Truth to be clear.

[Simone Cimminelli @Cimminelli]

@OliverMolander they are all walking zombies

[Simone Cimminelli @Cimminelli]

@agupta wrong alignment

[Alex Taylor @AlexTaylorNews]

Australians can now live & work freely in the EU for 4 years and vice versa

That means they now have 𝒎𝒐𝒓𝒆 EU rights than British people. Free movement offered millions of us fantastic opportunities but Brexiteers slammed that door shut, most shamefully on their own children

[Simone Cimminelli @Cimminelli]

@adcock_brett basically another note taking app

[Jvnior @Jvnior]

🚨🇱🇧 BREAKING: Israel is completely ETHNIC CLEANSING civilians in Lebanon and world is 100% silent on this.

Don't be silent. Repost this. Stand with Lebanon.

[Esta @TheOnlyEsta]

Las Vegas understands the assignment‼️

Don’t get distracted‼️