Cindry

Open science for SEA. built on Base.

[Cindry @cindryprotocol]

TaliBone #042 — Thymidylate kinase
Cholera · A5F6P9 · pLDDT 97 (Gold)

Blocks this enzyme → stops V. cholerae from copying DNA.

Cholera is gaining antibiotic resistance. Millions of infections/year. Mostly tropical Asia.

Minted by adelaxelazel.base.eth
https://t.co/YfCok7QvhG

[Cindry @cindryprotocol]

Philippines.

TB: 700K cases/year. 3rd globally.
Dengue: 200K cases/year. National epidemic in 2019.
Leptospirosis: 15K cases/year. Spikes after every flood.

All three: SEVERE funding gap.

This is what the Cindry disease map shows.

https://t.co/PvERPshcCO

[Cindry @cindryprotocol]

M. leprae has one of the most stripped-down genomes in biology.

Over millions of years inside human hosts, it lost most of its DNA repair machinery.

DNA ligase is one of the few it kept. The bacterium survives by doing less — not more.

[Cindry @cindryprotocol]

TaliBone #3 — DNA Ligase

Disease: Leprosy

pLDDT: 89 (Ivory tier)

Most people think leprosy is gone.

Indonesia has the 3rd highest burden in the world.

[Cindry @cindryprotocol]

the data exists. the funding doesn't. we're fixing that.

[Cindry @cindryprotocol]

Southeast Asia. 680 million people.

Indonesia alone: 1 million TB cases a year.

Ranks 2nd globally for disease burden. we built a map.

https://t.co/1gSjY1VAfy

[Cindry @cindryprotocol]

dengue. TB. malaria. 10 diseases. 10 proteins. fully on-chain SVG art, no IPFS, no external URLs. just the structure of the thing itself.

[Cindry @cindryprotocol]

10,000 TaliBones. each one seeded from a real protein in the AlphaFold database. the rarity comes from the science — not from a random number generator.

[Cindry @cindryprotocol]

the website is live.

cindry is an experiment — DeSci for Southeast Asia. NFTs backed by real protein data. a treasury that funds open science. dengue, TB, the diseases nobody else is paying attention to.

we don't know if it works yet. that's the point.

https://t.co/YfCok7QvhG

[Cindry @cindryprotocol]

gm