Clemence Delalande

Pharmacist, doctor, part-time artist, curious about everything. On its way to a new exciting adventure

[Clemence Delalande @ClemyDela]

Need an inhibitor to study DHHCs, we got you covered!

[bryan dickinson @chembioBryan]

Happy to present our newest work! Grown out of frustration with current chemical tools, we developed a new pan-active DHHC inhibitor for the study of protein S-acylation (palmitoylation)

https://t.co/IzDw7JkZJG

[Clemence Delalande @ClemyDela]

@Topiramatee Merci pour ce super thread! Migraineuse depuis des années et pharmacienne aussi, j’aide au mieux les autres migraineuses qui passe à la pharma et c’est pas facile vu comment certaines personnes sont encore mal diagnostiquées ou mal traitées 😥

[Clemence Delalande @ClemyDela]

@skepteis @WUR Congrats!

[bryan dickinson @chembioBryan]

Excited to share our group's most recent work out today in @CellReports:

In this paper, we discover ERK1/2 are regulated by dynamic lipidation - illuminating a new layer of control for these critical cellular kinases

https://t.co/O98Vz0y2qp

1/n

[The Nobel Prize @NobelPrize]

BREAKING NEWS:
The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”

[Clemence Delalande @ClemyDela]

New paper with a lot of cool molecules is out to tackle DHHCs inhibition! So happy to see our latest effort going out 😀

[bryan dickinson @chembioBryan]

Check out our most recent work on DHHC inhibitors! Lovely paper led by group members Saara-Anne and @ClemyDela, along with help from @LanT_763 and @CBwolfTQ. Our first true medicinal chemistry paper...cool insights and A LOT of molecules 🙃

https://t.co/AlgeLzEeNu

[bryan dickinson @chembioBryan]

Check out our most recent work on DHHC inhibitors! Lovely paper led by group members Saara-Anne and @ClemyDela, along with help from @LanT_763 and @CBwolfTQ. Our first true medicinal chemistry paper...cool insights and A LOT of molecules 🙃

https://t.co/AlgeLzEeNu

[Clemence Delalande @ClemyDela]

Very thankful about the opportunity to share experience with TransCure fellows and reconnect with others. So much nostalgia being there for this last retreat!

[Hugues Abriel @[email protected] @SwissIonChannel]

Another star @NCCR_TransCure alumni @ClemyDela coaching a fellow during our last retreat @uniofbern @unibern! Very appreciated!

[Daniel Probst @[email protected] @skepteis]

Auch auf Deutsch 😉

[Daniel Probst @[email protected] @skepteis]

Some covers for academic journals I could design.
I always like to pack some actual data into it. The first two contain scatter plots, the third a ridge plot, and the fourth the 3D PCA of @DrugBankDB molecules in VR.
#ScienceTwitter

[Clemence Delalande @ClemyDela]

@av_thakkar @reymondgroup @AstraZeneca Congratulations !! 🍾

[Universität Bern @unibern]

Scientific progress should not be held up by politics. Global challenges do not stop at borders. The #unibern is supporting @Stick2Science for an open and inclusive European Research Area.
Sign here ▶️https://t.co/3opFuIJe7U

@C_Leumann @SwissIonChannel

#StickToScience

[Clemence Delalande @ClemyDela]

Very cool to see TRP channel brought to light with this year Nobel prize! So much to learn still from this class of ion channels

[The Nobel Prize @NobelPrize]

David Julius – awarded this year’s #NobelPrize in Physiology or Medicine – utilised capsaicin, a pungent compound from chilli peppers that induces a burning sensation, to identify a sensor in the nerve endings of the skin that responds to heat.

[bryan dickinson @chembioBryan]

Our new DHHC inhibitor story is out now in @ChemicalBiology. This was a huge amount of work over years and required an incredible team effort. Let us know if you want some CMA - and look out for more molecules and screening approaches coming next!

https://t.co/gFlekeztIE

[Clemence Delalande @ClemyDela]

@chembioBryan Felt very lucky to have such an enriching and inspiring experience in your lab @chembioBryan ! Loved my time there and hope to come back one day to Chicago.

[Clemence Delalande @ClemyDela]

@SwissIonChannel Congrats! Amazing to see this new results on CBA and NBA

[Clemence Delalande @ClemyDela]

Finally! 💉

[bryan dickinson @chembioBryan]

Happy to present our newest work! Grown out of frustration with current chemical tools, we developed a new pan-active DHHC inhibitor for the study of protein S-acylation (palmitoylation)

https://t.co/IzDw7JkZJG

[Daniel Probst @[email protected] @skepteis]

I tried to keep it simple, so yes, I left a lot out :-).

[Clemence Delalande @ClemyDela]

@skepteis Indeed and somehow quite cold in winter (up to -20 degree Celsius). More thdd et reason not to use those kind of windows