Tian Qiu

Postdoc in the Nathanael Gray Lab @Stanford.
Ph.D in the @chembioBryan Lab @Uchicago.
Alum of @Tsinghua_Uni.
Researcher in chemical biology.

[bryan dickinson @chembioBryan]

So, if you or someone you know thinks they can actually predict PPIs, prove it. Here is a link to our blinded protein sequence data:
https://t.co/mq7PHh73F2
5/n

[Pascal Devant @pascal_devant]

The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis.
Congrats to Hongbo Luo and authors on this discovery, great to see the final version of this published! @BostonChildrens @harvardmed

https://t.co/9E2SetzxfG

[Pavel Kielkowski @pavelkielkowski]

Let's do the right click! In chemical proteomics chemoselectivity of the CuAAC is crucial. Andreas Wiest in our group found that formation of the ubiquitous thiotriazole byproduct during the click reactions can be easily diminished: https://t.co/5uKlRx3n6i. Congratulations!

[Tian Qiu @CBwolfTQ]

@rmoellering14 @UChicago @UChiChemistry Congratulations!

[Kelvin Lau 🧬🧪💎 @klausenhauser]

Lets do a retro discovery of an unreleased product @Cytiva. Who thanks twitter can explain this entire process before the marketing info comes out 🤣

[Tian Qiu @CBwolfTQ]

Congratulations to my PhD advisor @chembioBryan for #100 papers!! #101 is already on the way and hope more will come out soon

[bryan dickinson @chembioBryan]

Finally, on a personal note, this is paper #100 for me. That feels kind of crazy....but lots of work left to do!!

https://t.co/woemFjrLDM

6/n

[Tian Qiu @CBwolfTQ]

Glad this work is finally out! It was a pleasure contributing a small part to this informative paper.
Fun fact: Using four (4) different assays to determine DHHC writers for ERK protein is not fun.

[bryan dickinson @chembioBryan]

Excited to share our group's most recent work out today in @CellReports:

In this paper, we discover ERK1/2 are regulated by dynamic lipidation - illuminating a new layer of control for these critical cellular kinases

https://t.co/O98Vz0y2qp

1/n

[Journal for ImmunoTherapy of Cancer @jitcancer]

Let’s take a closer look at the recent #JITC article: Senescent cancer cell vaccines induce cytotoxic T cell responses targeting primary tumors and disseminated tumor cells. https://t.co/9Sh1rwMpCc 1/6

[UChicago Medicine Comprehensive Cancer Center @UCCancerCenter]

Stephen Kron, Professor @UChicago publishes his recent findings in the journal @CellChemBiol. His work demonstrates the role of telomerase reverse transcriptase in cancer growth and therapy resistance.
@UCCancerCenter @UChicagoMed
https://t.co/gHjUsTBGSH

[bryan dickinson @chembioBryan]

Check out our most recent work on DHHC inhibitors! Lovely paper led by group members Saara-Anne and @ClemyDela, along with help from @LanT_763 and @CBwolfTQ. Our first true medicinal chemistry paper...cool insights and A LOT of molecules 🙃

https://t.co/AlgeLzEeNu

[Rafa Nadal @RafaelNadal]

Dear Roger,my friend and rival.
I wish this day would have never come. It’s a sad day for me personally and for sports around the world.
It’s been a pleasure but also an honor and privilege to share all these years with you, living so many amazing moments on and off the court 👇🏻

[bryan dickinson @chembioBryan]

Very exciting paper out on discovery that Cln5 is a protein S-Deacylase! This is the second protein annotated using our probes (in addition to Abhd10) and we are thrilled to have been able to contribute to this work. https://t.co/SDHWSeaWIg

[Francesca Lorandi @FrancescaLoran2]

The past week I was involved in a lab accident. I'm fine, just wearing a neck brace for a while and I’ll have a new tooth. I'm very grateful for all messages and help.
But we need to talk and do more about safety in chemistry labs. 1/n

[Madeline E. Kavanagh @mads_chem]

Congratulations to the 2022 @WolfPrize_ #chemistry laureates Prof. Ben Cravatt @scrippsresearch , Prof @CarolynBertozzi and Prof Bonnie Bassler @Princeton. A tour de force in chemical biology!

[Dr Matt Benton @DrMattBenton]

Well hello! After making a new red fluo histone line in Dros, @MBattistara found the existing mCherry line to have much higher background than her new one. Maybe this is why!

https://t.co/5iejFqFyvL

[Robert Spitale @SpitaleLab]

A real joy in science is creating enabling technologies and then working with the best people to see them reach their full potential. Congratulations to @JMTali on Halo-Seq to characterize subcellular transcriptomes, in situ.

https://t.co/Dp74udPgR2

[Jake Yeston @JakeYeston]

Also in @ScienceMagazine this week, Wei Han's group reports an iron catalyst with a disulfide ligand to oxidize arenes to phenols https://t.co/usIH90u9SF

[Iain Cheeseman @iaincheeseman]

With the new academic year starting, and many people beginning fresh as graduate students, post-docs, or junior faculty, I have been thinking a lot about the core philosophies that govern my own perspectives on science. So I thought I would share.
Welcome to The Tao of Cheese

[Feng Zhang @zhangf]

We are really excited to share our work on a new modular RNA delivery technology called SEND, built from endogenous components found in the mammalian genome. @ScienceMagazine https://t.co/0HRvKkDAFV