Researchers @XTALUCIBIOFCTN1 uncover how metal-dependent formate dehydrogenase enzymes, key for CO2 reduction, are inactivated by oxygen. This discovery could pave the way for more robust bio-inspired catalysts.
More: https://t.co/9hgFOIPRlJ
#CO2Reduction#ClimateChange
And another one, maybe without the training bias. Should bind specifically promoter region ATTTTAGTCGCGCCTAAAAT and it does again! Left is crystal structure, right is the AlphaFold3 model. Promoter is in red.
📢 ONLY ONE WEEK LEFT
to submit your abstract to
2024 #Inorganic & Bioinorganic #Chemistry Conference, #2024IBiCC
📅: May 16 - 18, 2024
🌏: Lisboa 🇵🇹
https://t.co/08GlPnmb7G
Check out our newest preprint reveiling a Mn sensor from #Deinococcus, bound to the promoter region of MntH. Mn ions accumulation is crucial for ROS scavenging & proteome protection in this highly resistant bacterium. @esrfsynchrotron@UCIBIO_Research
https://t.co/3nwmLHeuft
📢 2024 #Inorganic & Bioinorganic #Chemistry Conference
#2024IBiCC
📅: May 16 - 18, 2024
🌏: Lisboa, Portugal 🇵🇹
⚠️ Key dates:
abstracts submission: April 1, 2024
early bird registration: April 15, 2024
More info: https://t.co/nN8lTcuPNp
Our first preprint! Very proud of the excellent work by
Vilela-Alves and coworkers, demonstrating at the atomic level how a W/SeCys-Fdh gets inactivated by oxygen. @FCTNOVA@UCIBIO_Research@i4HBio @XTALUCIBIOFCTN1 @NMRFCTNOVA1@itqbnova@esrfsynchrotron https://t.co/zX05iHhy0g.
Check out our work unraveling the molecular basis for the unusual oxygen tolerance of W-Sec-FDH: a redox switch based on an allosteric disulfide bond regulates both high CO2 reductase activity and oxygen tolerance. https://t.co/yToIOU2rj7 #enzymatic#CO2reduction +
Congrats to Delfim Manuel Araújo Ferreira for his PhD in Molecular #Biosciences! 🎓 👏
His #research, "Unraveling the metabolic pathway of dissimilatory sulfate reduction", was supervised by @InsCardosoPere1 and co-supervised by Sofia Venceslau.
#TeamNOVA#MolBioS@NOVAunl
Congratulations to Cristiano Mota @XTALUCIBIOFCTN1 who coordinates one of the approved projects in the Call for Cooperation in Science between Portugal & Germany FCT-DAAD for 2023/2024, with a German team @unihh and T-REXX beamline at PETRAIII
More https://t.co/qHgi7pMNYF
#UCIBIO
New study developed by @XTALUCIBIOFCTN1 @NMRFCTNOVA1@UCIBIO_Research@FCTNOVA unveiled the mechanisms of 3 inhibitors to an important human drug metabolizing enzyme by combining X-ray crystallography, NMR spectroscopy and kinetic assays.
@ACSBioMed
More: https://t.co/AqaGOHN1DK
Interrogating the Inhibition Mechanisms of Human Aldehyde Oxidase by X-ray Crystallography and NMR Spectroscopy: The Raloxifene Case https://t.co/jRmxtOCSH0