@NYCMayor pls put a stop to this. The suffering of these horses is something that can end with your help. For that horse to die in Central Park, he suffered so much to meet that end. #centralparknyc
Scientists have discovered a promising new way to help the immune system detect and attack hidden cancer cells.
A first-in-class drug called GRWD5769 (an oral ERAP1 inhibitor) has shown encouraging early results, shrinking tumors in patients with six different types of advanced cancer: lung, liver, bladder, cervical, head and neck, and colorectal.
In a Phase 1/1b clinical trial (EMITT-1) involving 83 heavily pre-treated patients across multiple countries, tumors shrank in 26 participants. Of those, 15 experienced reductions of at least 30%. Many patients had already failed prior therapies, including immunotherapies.
The drug works by blocking the enzyme ERAP1, which cancers often use to “edit” their surface proteins and evade immune detection. By inhibiting ERAP1, GRWD5769 alters the tumor’s antigen presentation, effectively removing the cancer’s invisibility cloak and making the cells more visible to the immune system. It was tested in combination with the PD-1 inhibitor cemiplimab (Libtayo).
Particularly strong signals were seen in certain hard-to-treat cancers. For example, disease control for at least six months was achieved in 51% of colorectal cancer patients and 55% of lung cancer patients in the expansion cohorts.
While these early results are promising, experts emphasize this is still an early-phase study. Larger trials are needed to confirm efficacy, durability of response, and impact on long-term survival.
If successful, this approach could expand the number of patients who benefit from immunotherapy — which currently works in only about one-third of cases.
[Grey Wolf Therapeutics. “EMITT-1: Clinical and pharmacodynamic activity with the oral ERAP1 inhibitor GRWD5769 and cemiplimab in 6 completed phase 1b expansion cohorts in solid tumors...” Presented at ASCO Annual Meeting, 2026]
@NBA these refs are making such bad calls and not calling clear violations. They should be penalized for 2 bad calls in a row. We don’t pay to see a ref change the outcome of a game. #knicks
Ossoff: Last September, the President of Kazakhstan calls Donald Trump and says he wants to grant tungsten mining rights to an American company. And the very next month, Eric and Don Jr. get a stake in the American company pursuing the mining deal.
Six days later, six days after Prince Eric and Prince Don get their stake, Kazakhstan announces this company will get, “The largest known undeveloped tungsten resource in the world.” A few more weeks go by, and then the U.S. government, run by their father, sets aside 1.6 billion of your tax dollars to fund and finance their mining project. In Kazakhstan.
All this while you pay more for gas, for groceries, for health care, and that's just the tip of the iceberg.
This is so insanely corrupt, I can’t even believe it.
More than half the donors to Trump’s $400 million White House ballroom just won over $50 billion in new federal contracts in six months.
And here’s the part that should make your blood boil.
Sixteen of these 27 donors were facing federal enforcement actions, antitrust reviews, labor cases, securities charges. Many of those cases have been quietly dropped or scaled back since Trump took office. You write a check, your legal problems disappear. That’s not a coincidence.
The White House won’t even release the full donor list. They’re hiding it on purpose, because daylight is the one thing pay-to-play can’t survive. A federal judge already ruled ballroom construction has to stop until Congress authorizes it.
Government is supposed to serve the people, not auction itself off to the highest bidder. When access goes to whoever pays the most, working families always end up paying the price.
We either end the corruption, or the corruption will end us.
https://t.co/4MGFzSseFl
#URGENTE: La ocupación en las playas del sur de Albania para construir el lujoso resort de Trump & Kushner se esta haciendo golpeando brutalmente y agrediendo a activistas pacíficos y legítimos propietarios de tierras que se atreven a defender su costa.
Mostremosle al mundo lo que implica la invasión de EEUU a naciones que no pueden defenderse por la via de la guerra, esto es lo que busca Trump, adueñarse de tierras, recursos y riqueza de pueblos indefensos.
¿Por qué no lo hacen con China o Rusia?
Esto quieren hacer en #Colombia #Cuba y #Mexico, solo evitando que la derecha regrese al poder podremos defendernos de su entregismo.
#Albania #EEUUTerroristState
A message to all sane Republicans:
He pardoned 1,600 violent criminals.
You said nothing.
He bulldozed the East Wing.
You said nothing.
He interfered with the release of the Epstein files. You said nothing.
He took over the Kennedy Center and renamed it after himself. You said nothing.
He accepted a $400 million airplane as a personal gift. You said nothing.
He threatened Canada, Cuba, Denmark, Greenland, Venezuela, Colombia, and Brazil. You said nothing.
He tariffed just about everyone but Russia, causing inflation and instability worldwide. You said nothing.
He attacked a nation during mediated negotiations. You said nothing.
His ill-conceived war killed 175 children on day one. You said nothing.
He alienated and insulted our allies. You said nothing.
His ICE Army terrorized and murdered U.S. citizens. You said nothing.
He committed murder on the high seas. You said nothing.
He co-opted the Justice Department and directed it to prosecute his political enemies. You said nothing.
It’s time to start talking.
A message to all sane Republicans:
He pardoned 1,600 violent criminals.
You said nothing.
He bulldozed the East Wing.
You said nothing.
He interfered with the release of the Epstein files. You said nothing.
He took over the Kennedy Center and renamed it after himself. You said nothing.
He accepted a $400 million airplane as a personal gift. You said nothing.
He threatened Canada, Cuba, Denmark, Greenland, Venezuela, Colombia, and Brazil. You said nothing.
He tariffed just about everyone but Russia, causing inflation and instability worldwide. You said nothing.
He attacked a nation during mediated negotiations. You said nothing.
His ill-conceived war killed 175 children on day one. You said nothing.
He alienated and insulted our allies. You said nothing.
His ICE Army terrorized and murdered U.S. citizens. You said nothing.
He committed murder on the high seas. You said nothing.
He co-opted the Justice Department and directed it to prosecute his political enemies. You said nothing.
It’s time to start talking.
@RonDeSantis@GovRonDeSantis In 2010, Florida voters amended that constitution by approving what are called Fair Districts amendments, which prohibit congressional or legislative redistricting to favor or disfavor a political party.
You are elected to do the will of the people and NOT the will of Trump.
@McCormickCorp why does your label and product state “PURE” when it is clearly NOT PURE? All of them. Not one pure extract. All have alcohol in them. Do not open near open flame 😳 #foodlies
@andrewrsorkin pls ask Bezos to help us understand the dichotomy between founding the Earth Fund and asking the county in which Blue Origin operates for a permit to dump waste water into the very important and incredibly biodiverse Indian River Lagoon. Wud luv to hear his take
Shark Tank Billionaire Kevin O'leary says 2 people fighting data centers in Utah are Chinese agents. Turns out its just 2 local girls in Utah, they make a hilarious video calling him the fuck out
@YourAnonNews@GabiFinlayson PLEASE sue him for liable. He just called y’all traitors. He accused you of TREASON… out loud. He would sue you for less.
Get tough. You can use the money to further your cause.