Ogün Adebali

Associate Professor at Sabancı University

[Ogün Adebali @compGenomics]

1/n
UV radiation disrupts genome integrity, but how does the 3D genome facilitate DNA damage response (DDR)? Our latest study with @vogulcankaya reveals how UV-induced genome reorganization enables efficient repair. 🌟🔬
🔗 https://t.co/xDcz9dX1P1

[Ogün Adebali @compGenomics]

The PURE summer program application period is over. We received a great interest. Thank you! However, the number of applications is far greater than we can accept. ~2000 applications for 8 spots in our lab. Now it is our turn to make the best decision.

[Ogün Adebali @compGenomics]

@AREWlker (wet experiments) and @berkayselcuk (analysis) are the co-first authors. @habibhobo performed MD simulations.

[Ogün Adebali @compGenomics]

🥳 We published our work co-led with @Hanyaloglu_Lab, in collaboration with @serdar_durdagi.

https://t.co/DARAiP5sYE

Differential conservation analysis identifies residues defining constitutive internalization in beta-adrenergic receptors

@AREWlker, @berkayselcuk, @habibhobo

[Ogün Adebali @compGenomics]

Take-home message: evolutionary information can do more than highlight “important residues.” It can help identify which residues encode subtype-specific behaviors, such as baseline trafficking/internalization.

[Ogün Adebali @compGenomics]

Getting prepared for my new course at home.

[Ogün Adebali @compGenomics]

Two comments after my course:

"After this course, I understand that I want to study bioinformatics"

"The course made me make sure that I have zero interest in Comp Bio"

Glad to see both. Knowing what you don't want to do is as important as knowing what you're interested in.

[Ogün Adebali @compGenomics]

@hamptonism More important than ever!

[Ogün Adebali @compGenomics]

Dear developers, in the era of AI, I urge you to specialize in a field. This field could be anything. Genetics is one of them. If you are interested, let's talk about where to start.

[LifeScienceAlliance @LSAjournal]

Have you already read this review?
Conserved 3D genome reorganization during DNA repair
@compGenomics @uzh_vetsuisse @fenssabanci @vogulcankaya https://t.co/aotuvV4f6x

[Ogün Adebali @compGenomics]

Just realized that our work was highlighted - some time ago - by a popular science platform. Written by a real person, not AI 🥰

https://t.co/BqHvRTgSIR

[Ogün Adebali @compGenomics]

I’m happy to co-author this review with our PhD candidate, @vogulcankaya! A big thanks to Drs Nägeli and Yancoskie for their lead. We’ll be sharing more updates from this team in the coming months. Stay tuned!

[LifeScienceAlliance @LSAjournal]

This review synthesizes findings from genomic, molecular, and disease studies that chromatin organization dynamically shapes diverse DNA repair pathways. @compGenomics @uzh_vetsuisse @fenssabanci @vogulcankaya
https://t.co/d6Yy9XNWzG

[bioRxiv Bioinfo @biorxiv_bioinfo]

Brendo: an open resource for uniquely transcribed genes in brain endothelial cells https://t.co/ZgfGl1QqOK #biorxiv_bioinfo

[Ogün Adebali @compGenomics]

Terrible comparison. Think about internet availability when it was first released.

[Greg Brockman @gdb]

AI product adoption is fast.

[Ogün Adebali @compGenomics]

(2/n)
Oct 20 at @itu1773 Öncelikli ve Yenilikçi Araştırmalar Çalıştayı
Nov 19 at @BilkentUniv MBG Departmental Seminar
Nov 21 at @METU_ODTU Departmental Seminar

There might be a couple more, currently uncertain...

Feel free to join.

[Ogün Adebali @compGenomics]

After a year away on my sabbatical, I accepted every seminar invitation that I could.

Here is the schedule:

(1/n)
Oct 4 at @itu1773 BioScenario
Oct 14 at Istanbul Univ - Evolution Club
Oct 17 at @kocuniversity MBG Departmental Seminar
Oct 18 at @UniBogazici BUEC IEEE