Coralie Sengenès

[Le Média Positif 🍀 @LMPositif]

🇫🇷 À Toulouse, la chercheuse Vera Pancaldi utilise l’intelligence artificielle pour mieux comprendre le cancer du pancréas, l’un des plus complexes et résistants aux traitements. Son travail consiste à analyser d’immenses données biologiques afin d’identifier de nouvelles pistes thérapeutiques et améliorer la prise en charge des patients. ���� (France Bleu)

📸 Sébastien Brethenou

[Coralie Sengenès @CoraSen]

Cadmium dans nos assiettes : protégeons nos enfants ! - Signez la pétition ! https://t.co/lvwju6ss25 via @ChangeFrance

[Rémi Mounier @RemiRmounier]

MuSkLE Excellence Scholarships, offering outstanding Master’s and PhD students the opportunity to join a cutting-edge, research-driven graduate programme in Lyon (France):
https://t.co/5WZt09y7Tv

[Rémi Mounier @RemiRmounier]

https://t.co/rUV2FpS3MB?

[Kris Selin @kris_honneur]

Un simple geste pour prolonger la chaîne humaine ✨️
📸 Repartagez le dessin de #Lola
Que son visage continue de se propager, de cœur en cœur 🤍✨️jusqu'à toucher toutes les âmes.

[Perrimon Lab @PerrimonLab]

https://t.co/H5b5ROz9EY

[Dylan Thompson @DrDylanThompson]

New Research Associate opportunity in nutrition and metabolism at @UniofBath funded by @BBSRC - closing date 20th August. Come and join @CNEM_Bath!

https://t.co/OQomXrVPuo

[Julien Gondin @GondINMG]

Join us!

[ANR - Agence nationale de la recherche @AgenceRecherche]

📢 #France2030 L’appel à projets (AAP) du programme de recherche exploratoire « Organes et organoïdes sur puces » (MED-OOC) est en ligne.

📅 Date limite de dépôts des dossiers : 27/05/2025 - 11:00
🔗 https://t.co/RLQq3MI7ES

[João Cardeira-da-Silva @joao_cardeira]

Interested in #cardiac_regeneration, #zebrafish, #aging, and the #immune_response? We are looking for a candidate to apply for a PhD opportunity from the CARe graduate school @CareGraduate in Toulouse!

[Association for Women in Science @AWISNational]

We love to see everyone #StandUpForScience!

[Institut de Myologie @Inst_Myologie]

📢 #StandUpForScience Le 7 mars, mobilisons-nous en écho à l’action américaine Stand Up for Science ! 👉 https://t.co/wjnKaN6vgV

[Cell Metabolism @Cell_Metabolism]

New! Online now: https://t.co/S1pp8sSkky: A knowledge portal integrating clinical and experimental data from human adipose tissue https://t.co/Adcu0Zy4lC

[Cell Reports @CellReports]

scCamAge: A context-aware prediction engine for cellular age, aging-associated bioactivities, and morphometrics https://t.co/gibvWXsZ46

[Julien Gondin @GondINMG]

Happy to share our work on the effects of neuromuscular electrical stimulation training on myonuclear accretion and hypertrophy https://t.co/XiPtG5hule
Thanks @aurelief1624 @AZavoriti @BenChazaud and all the coauthors
Funding @MyoNeurALP @Canceropol97501 @iNeuroMyoGene

[Javier Gonzalez @Gonzalez_JT]

I was surprised to hear @DoctorChrisVT say “the whole idea that you can burn more calories by doing exercise was funded, if not by Coca Cola, then by the soft drinks industry”

https://t.co/uKD7czI5sW

Is this true? 👇
@Ri_Science

Cc @theproof @NutritionMadeS3 @GilesYeo

[Rita Strack @rita_strack]

It was an absolute dream to help with this Method of the Year! SPATIAL PROTEOMICS gets a well-deserved spotlight! Thanks so much to all the authors who contributed their comments! @RongFan8 @BodenmillerLab @leeat_keren @labs_mann @DanielaQuail

[Martin Picard @MitoPsychoBio]

If we look at thousands of proteins (i.e., signals) in the human blood, the protein most associated with chronic physical and mental illnesses is the **same protein** as the top marker for mitochondrial diseases: GDF15

When mitochondria cannot flux energy properly, the cell makes and secretes GDF15 in the blood to alert other cells

Some highlight by Cynthia Liu in our group:
- GDF15 is the top predictor for most diseases

- GDF15 associated with diabetes is among the most significant protein-prevalent disease associations
Based on p-value, GDF15 was most significantly associated with disease.

- “GDF15 was associated with the most diseases, containing 205 prevalent and 397 incident diseases, generally acting as a risk factor except for three incident diseases (respiratory diseases affecting the interstitium, disorders of magnesium metabolism, and peripheral artery disease).”

- “GDF15, similar to its high ranking with protein-disease pleiotropy, ranked second for protein-trait associations, boasting a substantial 428 associations.”Significant associations with many lipid metabolite markers.

- Mental disorders like anxiety disorders, depression, and mood disorders, along with mental health-related traits, also exhibited substantial proteomic signatures including elevated GDF15

- “The fluid intelligence score and various types of dementia shared significant proteins such as NEFL and GDF15 (Figure 2G)”

- “GDF15, the protein with pleiotropic effects, was causally associated with several autoimmune diseases, including ulcerative colitis and rheumatoid arthritis (Figure 6B).”

Data from >53,000 people in the UK Biobank

Full paper here:
https://t.co/F3dn16E0t2

Resource to explore your favorite protein or disease/trait of interest: https://t.co/BjpilkdtHW

[Sarry Lab @jeansarry]

Lucky you! Fantastic! @isaperarnau

[Coralie Sengenès @CoraSen]

Yaaaa!!!