Excited to share this paper from @yiechanglin showing how lipids can move between bacterial membranes along the bridge like protein TamB. Also happy to be able to post the cool movie. ๐ฅ๐ #MDsimulations#StructuralBiology https://t.co/9c395prYOx
How does your immune system tell pathogenic RNA from your own, even though theyโre made of the same stuff? Our latest paper with
@GantierLab
shows some self RNA act as an off switch preventing autoimmunity in the absence of pathogens. ๐งฌ๐ฌโญ https://t.co/GyNvzuVaJj
Beginning 2026 with a flipping good paper๐OSCA/TMEM63 proteins do double duty: theyโre ion channels andmechanically activated lipid scramblases helping reshape membranes and survive mechanical stress. ๐@yiechanglin@Charles_D_Cox
https://t.co/w3ZkTrAcf8
Great to see this paper with @whoiselainetao out in print at the Biophysical Journal. Using Alphafold to study conformational transitions in 32 voltage-gated ion channel superfamily members #ionchannel#AI#StructuralBiology
https://t.co/fm5UNwgpoE
2 yrs ago @yiechanglin sent me this of lipid scrambling by OSCA1.2. Now we show itโs common to WT OSCA/TMEM63 proteins, mechanically activated, cholesterol dependent, and protects cells from damaging forces. Awesome collab with @Charles_D_Cox
&Zhang lab. https://t.co/ummUuLps3J
๐We are hiring! Seeking a postdoc to use molecular dynamics and AI to understand how ion channels are regulated by membrane lipids๐
Join us at @ourANU with amazing collaborators and great working conditions!
Apply: https://t.co/sb24UaQGir. Us: https://t.co/5B6ibl9lbw
๐We are hiring! Seeking a postdoc to use molecular dynamics and AI to understand how ion channels are regulated by membrane lipids๐
Join us at @ourANU with amazing collaborators and great working conditions!
Apply: https://t.co/sb24UaQGir. Us: https://t.co/5B6ibl9lbw
Excited to share @john_d_tanner's new work in Nat Coms! We demonstrate how PfCRT, a polyspecific peptide transporter, turns into a drug transporter for antimalarials like chloroquine and why this causes a fitness cost for the malaria parasite (1/2)
https://t.co/TkQBrNabTA
Also bittersweet to announce the final work of @whoiselainetao in our lab, using AF2 to study conformational transitions in 32 voltage-gated channel superfamily members ๐คฉ we're so excited to watch you Nav-igate the next steps of your career, Dr. Tao ๐ฉ
https://t.co/zbgJUKUq2H
Bittersweet to announce YC's final work in our lab. We are so proud of everything she's accomplished (incl. this beautiful study showing how the TAM complex facilitates lipid flow between the bacterial inner & outer membranes). We can't wait to see what you do next, Dr. Lin ๐คฉ
1/ In my final project as part of the @CorryLab, we show the bacterial TAM complex facilitates the spontaneous flow of phospholipids from the IM to the OM in MD simulations..
https://t.co/74LBAaoP7I
Thrilled to share our latest preprint from @yiechanglin & @ciara__wallis showing AF2-Multimer and AF3 can quickly & accurately predict the oligomeric states & structures of proteins (& maybe can identify multiple biologically relevant oligomeric states ๐)
https://t.co/5pHSKuAMfP
Big congratulations to the very sharp @whoiselainetao who submitted her PhD last week! Our greatest Nav channel expert is rumoured to be joining the dark side of Kv. #drtao#phdone@ourANU@scienceANU ๐ช๐๐ฉโ๐ฌ๐ฉโ๐
Big congratulations to @Riottowow for winning an Anders Early Career Award at @LorneProteins #lorneproteins2025 ! Presenting his work on the lipid lined pore of the OSCA mechanosensitive channel.
Proud of our latest work w/ the Zhang lab showing from structure & simulation how XPR1, the only known human Pi exporter, is regulated by InsP8 & KIDINS220 + Pi selection/permeation by a channel-like knock-kiss-kick mechanism
๐ป @ciara__wallis@Riottowow
https://t.co/my7tGU5DEL
Excited to start the year with this lovely paper with @whoiselainetao showing that drugs that inhibit sodium channels bind in a range of sites within the pore cavity rather having a single distinct pose.
@JGenPhysiol@scienceANU@NCInews
Tao and Corry @CorryLab@ANU_RSB_BSB investigate the binding of sodium channel inhibitors to the Naแตฅ1.5 pore using simulations, revealing promiscuous, polyspecific binding at the fenestrations and central cavity. https://t.co/sBg4Gx6iCz
Nav computer modelling as tool to understand fast inactivation: join us for the next worldwide sodium channel seminar given by Ben Corry on December 17th. More info on https://t.co/W3G6Q7QJO3. Mark your calendar and join the discussions!
We've just opened expressions of interest to EIGHT PhD scholarships in plant biosecurity! Each come with integrated placements in government or industry, awesome travel and professional development. #PhD#PhDposition#biosecurity https://t.co/yXvmi8m2r5
@ARC_Tracker I have noticed that our college internal EOI submission deadline is before the likely announcement of the DP25 outcomes... Are we meant to assume our current application will be rejected๐ค๐