Constantin Pape

Group leader @ Uni Goettingen applying Image Analysis and Deep Learning to large microscopy data in biology.
Also @cppape.bsky.social

[Constantin Pape @cppape]

How can we use foundation models such as (micro)SAM to improve electron microscopy segmentation? Check out our preprint! We found substantial improvements for nucleus, mito, and neurite-segmentation using initialization and semi-supervised learning with foundation models.

[François Chollet @fchollet]

The ideal outcome for science isn't a couple of labs using proprietary models and millions of dollars to crack trophy problems, it's to have millions of AI-aided human scientists who follow their curiosity and become way more ambitious

[Constantin Pape @cppape]

AGI when ChatGPT can convert a PNG to SVG without creating ugly crop boundaries in each rasterized element.

[Constantin Pape @cppape]

This research will help us to build better tools for interactive microscopy analysis --- stay tuned for more! For more details: https://t.co/94KnNtCXk7

Thanks to Caro for driving this work and all other co-authors!

[Constantin Pape @cppape]

Segmenting cells in microscopy is much easier these days thanks to foundation models. Can we use these models for other tasks, e.g. cell classification? See our latest work! We find big improvements for object and pixel classification compared to classical approaches.

[Constantin Pape @cppape]

We compare foundation models (SAM and DINO variants) with classical features from ilastik and supervised learning. The FM features outperform classical approaches. Attentive probing is better than RF, but too slow for interactive use. See example results in the fig.

[Constantin Pape @cppape]

Want to learn about the latest trends and developments in bioimage analysis? Join us for the GLOBIAS workshop in Dortmund this November! I will be hosting a session on foundation models / AI. https://t.co/x39KwHRUHW

[Constantin Pape @cppape]

Learn more here: https://t.co/JBRETgN4pG
Thanks to Marei for leading this work!

[Constantin Pape @cppape]

How can we use foundation models such as (micro)SAM to improve electron microscopy segmentation? Check out our preprint! We found substantial improvements for nucleus, mito, and neurite-segmentation using initialization and semi-supervised learning with foundation models.

[Constantin Pape @cppape]

We are so behind in Europe that our fanfic version of AI 2027 drops a year later and is only Europe 2031.

[Tom Chivers @TomChivers]

Here's a project I've been working on recently: a vision of what happens if Europe doesn't take AI seriously, inspired by AI 2027 https://t.co/b6PBu3nmeK

[Constantin Pape @cppape]

Did it actually answer someone what a mitochondrion is 😱😱😱

[Anthropic @AnthropicAI]

The US government, citing national security authorities, has issued an export control directive to suspend all access to Fable 5 and Mythos 5 by any foreign national, whether inside or outside the United States, including foreign national Anthropic employees.

The net effect of this order is that we must abruptly disable Fable 5 and Mythos 5 for all our customers to ensure compliance.

Access to all other Claude models is not affected.

We apologize for this disruption to our customers. We believe this is a misunderstanding and are working to restore access as soon as possible.

Read our full statement: https://t.co/bwn0sximKZ

[Leo 🏴‍☠️ @leostera]

i need someone at @OpenAI and @AnthropicAI to teach the models that while prototyping, backwards compatibility is just a bad idea

[Constantin Pape @cppape]

Sorry to break the news, but the job of twitter hypeman was automated a few years ago already.

[Dr. Thomas Ichim @exosome]

Today we all lost our jobs.....

Three Nature papers showing that scientists in the conventional sense are obsolete

At least read the first one.... the AI replaced all things that the scientist does ....

https://t.co/zMsRLaaRDU

[EPFL Center for Imaging @EPFL_Imaging]

🔬 Imaging Seminar on Vision Foundation Models for Microscopy with Prof. Constantin Pape (@cppape) from University of Göttingen

📅 Mar 30, 17:00
👉 Registration: https://t.co/Do08h6budq

💡 EPFL PhDs:
Imaging Lunch w/ Prof. Pape
📅 Mar 31, 10:00
👉 https://t.co/Em5wb84I3g

[Constantin Pape @cppape]

Looking for a PhD position at the intersection of AI, imaging, and gene therapy? Apply for this position in my lab: https://t.co/IbnFHMX2k5

Part of https://t.co/d6uswTbITS that studies hearing, vision, and more.

Plus, you can create pretty pictures like the one below :).

[Davis Blalock @davisblalock]

🚀 Today we’re releasing FlashOptim: better implementations of Adam, SGD, etc, that compute the same updates but save tons of memory. You can use it right now via `pip install flashoptim`. 🚀

https://t.co/nRrLSpjnwV

A bunch of cool ideas make this possible: [1/n]

[Timothy Fuqua @timothy_fuqua]

I'm looking for a Swiss department to host me for an SNSF StG.

I research how gene expression evolves and emerges by combining wet lab + computational work in a variety of model systems. More: https://t.co/8SI3OwFDhJ

If your department might be a match, let’s chat!

[Constantin Pape @cppape]

Retweeting as an AC: Please sumbit your CVPR reviews ;)

[#CVPR2026 @CVPR]

Have you completed your reviews yet?

[#CVPR2026 @CVPR]

The #CVPR2026 review deadline is fast approaching: January 12, 2026.

If you face any difficulties, contact your Area Chair NOW!

Approach your reviews the way you would expect your own to be handled, and consult the reviewer guidelines here: https://t.co/oO1FOsaoe9

[Talia Ringer 🕊🪬 @TaliaRinger]

OK can you guys please dedicate even half the energy you collectively use critiquing Empire of AI to also critique the massive work of harmful pseudoscience by Yud and Soares that was also a NYT Bestseller