Critical Pressure

A new biotechnology company focussed on the development of new treatments for vasopressor dependent shock

[Critical Pressure @crit_pressure]

Excited to announce the launch of @crit_pressure with support of a £10m investment from @medicxi. Tackling septic shock with novel vasopressor therapies.

[UofG MVLS @UofGMVLS]

.@UofGlasgow, Professor James Leiper's research focuses on identifying new drugs to prevent the precipitous fall of blood pressure in septic shock. Through @crit_pressure, new candidate drugs have been identified & hopeful clinical trials will commence in future. #WorldSepsisDay

[Ashish K. Khanna, MD,MS,FCCP,FCCM,FASA @KhannaAshishCCM]

Dr.Jonathan Chow addresses the need for another vasopressor @SOCCA_CritCare

[Withers tech @WithersTech]

Congrats to our client Professor James Leiper and @crit_pressure on their $10 million Series A round from @medicxi for the development of a new drug to help patients in intensive care with severe sepsis. https://t.co/SqYlW97QvD #lifescience #medtech #investment

[Critical Pressure @crit_pressure]

Delighted to provide some of our published data and answer any questions. DM us your email address. https://t.co/5UPDtw0HsX

[Critical Pressure @crit_pressure]

A great evening, giving us the chance to put faces to the names of the excellent team taking @crit_pressure a reality. https://t.co/MuPj9twGd4

[Withers tech @WithersTech]

Congrats to our client Professor James Leiper and @crit_pressure on their $10 million Series A round from @medicxi for the development of a new drug to help patients in intensive care with severe sepsis. https://t.co/SqYlW97QvD #lifescience #medtech #investment

[Critical Care Pharmacy @PharmacyCCEd]

IV angiotensin II led to catecholamine dose reductions in vasodilatory shock with high pressor requirements #sccmcppjc #athos3

[Paul Young @DogICUma]

The 1st word on the 1st new class of drug for distributive shock in >50 yrs
https://t.co/xOzSZNMdPb

#ATHOS3

[Olga Peña PhD.🔬🦠🇨🇦🇨🇴 @OlgaPena]

I do think that we need to work stronger towards more research to understand the immunopathology of sepsis, the rapid development of microbe ID, and the possibility of using precision medicine approaches to manage and treat #Sepsis #Thread (3)

[Olga Peña PhD.🔬🦠🇨🇦🇨🇴 @OlgaPena]

Thus, clinicians need to stop working in silos and collaborate more with basic science researchers and patients so these goals can be achieved. There are still many unanswered biological and clinical questions in #Sepsis, so lots of research needs to be done! #Thread (4)

[Olga Peña PhD.🔬🦠🇨🇦🇨🇴 @OlgaPena]

Moreover, obtaining government funding for sepsis research is difficult. Therefore, having funding competitions organized by existent and newly created sepsis organizations to do #sepsis research would be really useful. #Thread (5)

[Olga Peña PhD.🔬🦠🇨🇦🇨🇴 @OlgaPena]

Finally, creating competitions to train the next generation of sepsis scientists and clinicians experts in #Sepsis is also highly needed, as currently there "almost" non-existent. #Thread (end)

[CambridgeCardio @Cambridgecardio]

Please spread the word about BHF-funded 4-year PhD studentships in Cambridge - application DL is 7 December: https://t.co/ACYtwQ7v2P https://t.co/2BiRPQDig9

[Intensive Care Society 💙 @ICS_updates]

Intensive Care Society State of the Art 2017 https://t.co/rKBoeCtXeI

[Dr. Paul Peter Tak @paulpetertak]

GSK is internalizing external innovation, bringing academics in house https://t.co/VWi1XxLFd2

[Critical Pressure @crit_pressure]

@BabrahamUK providing a great base with access to world class companies to help make our project a reality. https://t.co/zYYs1XL2rB

[Babraham Research Campus @BabrahamUK]

Award-winning #sepsis project gets $13M to create virtual company @crit_pressure https://t.co/s9ZRiRqjit @sciencescanner @medicxi

[Critical Pressure @crit_pressure]

The @TheBHF Translation award was incredibly valuable in bridging the gap between strong basic science and a model that appealed to commercial funders https://t.co/3xtgt1JdFd

[Dr. David Lyness @Gas_Craic]

#IFAD2017 https://t.co/lyNjiGsZfO

[Critical Pressure @crit_pressure]

The harmful effects of catecholamines are probably extensive, and the development of novel vasoactive agents will alllow greater insights into the impacts of adrenergic drugs on both vascular and immune cell responses. https://t.co/W7HfIB1jyx

[Karim Brohi @karimbrohi]

I would wager we're going to see a lot more data coming out about how bad catecholamines are for endothelia, the blood-brain barrier, and for brains... https://t.co/PI14RSIz5j

[Critical Pressure @crit_pressure]

@RxCelerate @medicxi @RxChemistry Many thanks. @RxChemistry responsive and flexible in moving @crit_pressure forward towards clinical trial in #sepsis