Carlos Silva Rosas

Full Professor of Neurology, University of Chile. Medical Education, Semiology, Neuroinfectology, Headache, Linguistics, Literature, Astronomy...

[EthelCiampiSCL @EthelScl]

⏰️Time is Brain 🧠 in MOGAD! Early and Effective acute treatment impacts disability and long-term outcomes. Start and escalate quickly if poor response. Tocilizumab also useful in severe attacks! @NeuroinmunUC @TheMOGProject
@TheSumairaFDN
https://t.co/wqp8acUWDd

[Neurology Journal @GreenJournal]

This study characterizes the risk of major congenital malformations in infants born to women using common antiseizure medication polytherapies during the first trimester. Read more: https://t.co/TTm7gTWv07

[W David Freeman, MD, FRSM, FNCS, FAAN @freemanwd]

🧠 Big news for stroke care from the T-FLAVOR trial!

Standard-dose tenecteplase 0.25 mg/kg beats low-dose alteplase 0.6 mg/kg—the standard of care in Japan and parts of East Asia—by achieving a nearly 3-fold higher rate of early substantial TICI reperfusion 10.3% vs 3.6% in acute ischemic stroke patients with large-vessel occlusion scheduled for mechanical thrombectomy ⚡️

Safety profiles were highly reassuring with similar rates of symptomatic ICH hemorrhage 2.8% vs 1.8% and 90-day mortality 6.5% vs 9.9% between groups 📉

This world-first head-to-head data positions tenecteplase as a highly promising thrombolytic option to streamline stroke workflows in regions currently relying on low-dose alteplase 🏥

Source: Inoue M, Hirano T, Fukuda-Doi M, et al. Standard-Dose Tenecteplase vs Low-Dose Alteplase for Acute Ischemic Stroke From Large-Vessel Occlusion: A Randomized Clinical Trial. JAMA Neurol. Published online June 1, 2026. doi:10.1001/jamaneurol.2026.1590

[Neurology Journal @GreenJournal]

Patients with iatrogenic cerebral amyloid angiopathy (CAA) exhibit higher amyloid burden and a distinct biomarker profile compared with those with sporadic CAA, supporting a divergent—possibly exogenous—mechanism of amyloid propagation: https://t.co/1GyujQ1KW3

[Rohit Sharma @piandro3142]

Great @Radiopaedia case by Dr Paul Ryan demonstrating Biffl grades I-IV blunt cerebrovascular injuries all on a single patient! 😱

https://t.co/6Y34ljpDit

[RADIOLOGISTS @DrAyubaD]

EASY ONE 🔥🔥

Elderly patient with chronic kidney disease on dialysis, presenting with confusion, tremors and choreiform movements.

MRI Brain (T2/FLAIR axial).

What is this classic sign? 👇

What are your differential diagnosis?

#MedX

[Annals of Indian Academy of Neurology @AnnIndAcadNeur]

Mechanical stress from dystonia can cause arterial dissection and stroke. @Divyani_Garg reports this combination in a case with genetically proven PKAN. Chronic iron deposition may also cause vascular fragility in NBIA spectrum disorders. @neuro_ian Link: 10.4103/aian.aian_21_26

[Hospital Barros Luco Trudeau @HBarrosLuco]

En el HBLT superamos las mil trombólisis, gracias al trabajo coordinado de nuestros equipos y lo conmemoramos en una ceremonia donde recibimos la certificación de Angels Initiative y nos acompañó el primer paciente trombolizado.

Con un 94% de efectividad, seguimos salvando vidas

[Nirmal Pandey MD DM Neurologist @nirmalregency]

And we use it in CNS TB.
Had quite a few favorable results.
Learned it from Dr Manish Modi.
And some more.. @docakx

[DrMansillaNeurologo @DrJPMansilla]

El MOGAD es el "gran impostor" de la neuroinmunología. 🧠 Pasa años confundido con Esclerosis Múltiple, pero tratarlo como EM puede exacerbar los brotes.
🚩 Red flags:
1️⃣ Neuritis óptica bilateral/severa.
2️⃣ Respuesta dramática a corticoides.
Abro hilo 🧵👇

[Carlos Silva Rosas @csilros]

@JordanHNewman @zach_london I agree

[Patricio Sandoval @neuropuc]

De @ACEVE_Chile me invitaron a dar una charla sobre “Cefalea y ACV” Un tema con muchas caras, mucha controversia, pero con buenos datos recientes que obligan q actualizarse! 🧠🥴
Inscripciones👉https://t.co/nrqkJaxQES

[Oren Gottfried, MD @OGdukeneurosurg]

Encephalopathies @drcyncity

[Nirmal Pandey MD DM Neurologist @nirmalregency]

@docakx seljalandsfoss.
Diagnosis ?

[Simen Sletten @simensletten]

FOOT DROP
Fibular (peroneal) neuropathy vs L5 radiculopathy!

You have a patient come in with a foot drop. There is no pain, but they have a history of low back pain. How do you differentiate between an L5 radiculopathy and fibular neuropathy in the clinic?

[XRP Ledger Announces @XRPL__A]

A young man 👨 with slowly progressing gait disorder and sleep apnea (due to recurrent tongue fall back at night)
Mother died of a similar illness
Mri shows this

[Oscar Arias @OACerebro]

Enjoy!

https://t.co/RKCakL3m1j

[Stanford Neurology & Neurological Sciences @Stanford_Neuro]

Jake Sossamon, PGY-1 Stanford Neurology resident, has launched The History of Neurology Podcast to explore the human drama, wartime breakthroughs, and accidental discoveries that shaped our specialty.

Episode 1: "The 'L' is Not Silent: The Secret History of Guillain-Barré" can be found on Spotify, Apple Podcasts, or Amazon Podcasts. https://t.co/2BTdTK74nT

[Patricio Sandoval @neuropuc]

Ha fallecido uno de mis maestros, el Dr Jorge Tapia Illanes. Profesor Titular de @FacmedicinaUC, Discípulo de Miller Fisher, Jay Mohr, Louis Caplan y EP Richardson. Pionero de la neuropatología y neurología vascular en Chile. Maestro de la neurología chilena @sonepsyn 2018, destacado por su aporte a la especialidad como gran docente formador de decenas de generaciones de médicos y neurólogos. QEPD 🕊️, muchas gracias por todo lo que aprendí de él y a seguir el legado de enseñar neurología “stroke by stroke” 🧠

[Carlos Silva Rosas @csilros]

@neuropuc @FacMedicinaUC @Sonepsyn Mis condolencias, Patricio. Asimismo, para todo el departamento. El Dr. Jorge Tapia fue un gran profesor.