ctDNA_DK

Dansk nationalt center for behandling vejledt af kræft-DNA i blodet. Centeret er en del af DCCC og støttet af Kræftens Bekæmpelse.

[Lars Dyrskjøt @LDyrskjot]

Exited to share the first results from the TOMBOLA trial presented at #ESMO24 by @JBjerggaard. We used tumor informed (WES; ddPCR) ctDNA analysis to guide Atezolizumab treatment after cystectomy using longitudinally collected blood samples.

Key findings:

•CtDNA-negative patients: 98% RFS at 1 year
•~50% are ctDNA-positive
•CtDNA-positive patients: 75% RFS at 1 year
•55% of Atezolizumab-treated patients cleared ctDNA & have no evidence of disease

Conclusion: ctDNA shows promise for treatment de-escalation (ctDNA-) and patient selection for adjuvant therapy (ctDNA+)

@Karin_Dem @IverNordentoft @SiaLindskrog @TrineStrandgaa1 @cancer_dk @DCCCcancer @CtdnaDK @AUHdk @AarhusUni

[ctDNA_DK @CtdnaDK]

Congratulation with your publication ✨

@ MarijanaNesic @madsheilskov @ ChristinaDemuth @amanda_fbj @IverNordentoft
@TennaVesterman @LDyrskjot @ClausLindbjerg

[ctDNA_DK @CtdnaDK]

New paper published in @IntJCanc addressing the selection of mutations to be used as ctDNA markers 🧬📃

Find the article here: https://t.co/D3IvpTMk2T

#ctDNA #CancerResearch
@moma_dk

[DCCC @DCCCcancer]

Så er der snart frist, hvis du vil have del i DCCC’s pulje! Send din ansøgning senest d. 22. april kl. 08 – læs mere: https://t.co/2WK4wRSr6j #samarbejdeomkræft #dkforsk

[ctDNA_DK @CtdnaDK]

In these days @CNAPS2024 is taking place in Graz, Austria. The center is represented with both participants and presentations about circulating tumor DNA 🩸🧬

Thank you for organizing this exciting conference, #CNAPS2024

#ctDNA #CancerResearch

[Claus Lindbjerg Andersen @ClausLindbjerg]

Great talk by Nadia Øgaard @GaardNadia on lower shedding of tumor DNA by Asymptomatic than symptomatic CRC tumors

@CNAPS2024 in Graz Austria

[Dept. of Molecular Medicine @moma_dk]

Gratis AUH-foredrag - også online - om strålebehandling og kræft-DNA i blodet ved @KSeiersen fra @DCPTprotons og @ClausLindbjerg fra @moma_dk den 27. februar kl 16

https://t.co/U5W9t4btAR

@CtdnaDK

[ctDNA_DK @CtdnaDK]

We wish you all a Merry Christmas and Happy New Year! 🎄

Thank you for the amazing collaboration! We look forward to more national research in ctDNA guided cancer treatment in 2024

#ctDNA #CancerResearch

@ClausLindbjerg | @LDyrskjot
@DCCCcancer | @cancer_dk

[Dept. of Molecular Medicine @moma_dk]

BLODPRØVE KAN HJÆLPE MED PRIORITERING AF KRÆFTBEHANDLING

Kræft-DNA i blodet hos patienter med de meste aggressive kræftformer stiger meget hurtigt.
Blodprøver kan være et redskab til prioritering af operationskapacitet på kræftområdet.

https://t.co/l5VB3BTVLH
📷Jens Løgstrup

[FYO @FYOncologist]

1000 tak @ClausLindberg fra @moma_dk for endnu engang at stille op lære fra dig af din store viden om #ctDNA 🙏🏼 det var en fantastisk god og meget pædagogisk gennemgang - spot-on til #ungekræftlæger til vores jule-webinar her til aften 🎄

[ctDNA_DK @CtdnaDK]

New paper out in @Annals_Oncology 🧬📢

Great work by @TennaVesterman and the research team of @ClausLindbjerg 🙌

👉 Read the article here: https://t.co/F1ZPoz4z7v

#ctDNA #CancerResearch

[Tenna Vesterman Henriksen @TennaVesterman]

📢 Our newest study on >800 CRC patients is now out 🧬
Read how:
1) Serial ctDNA = powerful recurrence predictor ⏳
2) Rapid ctDNA growth = detrimental to survival 📈
3) Personalized digital PCR = clinically practical for MRD analysis💡

��� Read more in @AnnalsofOncology! 📰

[ctDNA_DK @CtdnaDK]

Thank you for two inspiring days at the Annual Meeting 2023 last week!

Focus at the meeting:
👉Updates on ctDNA research DK
👉The way from trial to clinical implementation of ctDNA
👉ctDNA RECIST as a tool for monitoring therapy response
👉Collaboration and networking across DK

[ctDNA_DK @CtdnaDK]

Yesterday @ClausLindbjerg and Kåre Gotschalck visited Go'morgen Danmark on TV2 to tell about the promising research in ctDNA🧬

Funding from #KnækCancer has enabled the establishment of the national ctDNA Center and the research🙌

Find the piece at TV2 play

#ctDNA #gotv2dk

[CNAPS 2024 @CNAPS2024]

Welcome Jakob Skou Pedersen as a speaker at #cnaps2024, Prof. of Bioinformatics at @moma_dk. His current research focuses on the development of statistical methods for circulating tumor DNA (#ctDNA) detection and analysis of single-cell data.

[CNAPS 2024 @CNAPS2024]

Welcome @ClausLindbjerg, director of the “National Danish Research Centre for circulating tumor DNA guided treatment”, as a speaker at #cnaps2024. His research focuses on translation of basic molecular cancer knowledge into clinical tools.

[ctDNA_DK @CtdnaDK]

Read more about GUIDE-MRD here:

Website: https://t.co/6rHXPYmFDt
LinkedIn: https://t.co/ulQlYg8UYs

#ctDNA #liquidbiopsy #CancerResearch #dkforsk

[ctDNA_DK @CtdnaDK]

GUIDE-MRD, a new initiative about:
👉Defining reference standards for ctDNA testing
👉Clinical validation of ctDNA-based MRD detection assays
👉Integrating ctDNA testing into clinical practice
👉therefore, improving patient outcomes

@ClausLindbjerg is part of the consortium

[ctDNA_DK @CtdnaDK]

These days at #ESCP2023 in Vilnius @TennaVesterman and @morntoft from the ctDNA Research Center present some exciting research

@TennaVesterman about the possibilities of using ctDNA guided decisions - and @morntoft about the new RESPONSE project

#ctDNA #CancerResearch
@moma_dk

[Mai-Britt Worm Ørntoft @morntoft]

Wonderful talk by @TennaVesterman on ctDNA and colorectal cancer: a difficult topic made easy by a brilliant researcher. Surgeons be prepared! ctDNA is coming to your OR soon. #ESCP2023 @escp_tweets @moma_dk @cancer_dk

[Dept. of Molecular Medicine @moma_dk]

👩‍🎓PhD defence Thur September 21st at 10 AM

Amanda Johansen @amanda_fbj will defend her thesis "Blood-based detection of disease in patients with colorectal cancer" at @HealthAarhusUni.

Read more here:
https://t.co/D0W3koJGjy

#ctDNA #colorectalcancer

📸 AU Photo/Lars Kruse

[ctDNA_DK @CtdnaDK]

Open Postdoc position at the Medical University of Graz, Austria!

👉There is an open Postdoc position within GUIDE.MRD – an EU project to benchmark and validate available ctDNA assays for MRD detection.

#ctDNA #Postdoc

[ctDNA_DK @CtdnaDK]

Til Danske Kræftforskningsdage 2023 fortæller @Amanda_fbj om sin forskning i cirkulerende tumor DNA

Tillykke med at være en af de syv, der modtager prisen ”Exceptional Young Scientist Abstract”! 🎉

#DKD2023 #ctDNA #CancerResearch

@moma_dk

[DCCC @DCCCcancer]

Kan vi forudsige tilbagefald af kræft med en blodprøve? Det dykker @amanda_fbj ned i til #DKD2023, når hun i sessionen ’Aktuel Dansk Kræftforskning i Rampelyset’ går på scenen. Her vil hun få prisen "Exceptional Young Scientist Abstract". Tillykke! #SamarbejdeOmKræft #dkforsk