AI for Life Sciences at Anthropic. Former drug target hunter at Genentech and Bayer. Recovering marine biologist. Always an evolutionist. Views are my own.
Cheers, chills, and a standing ovation when RASolute 302 showed unprecedented survival on daraxonrasib for patients with progressive pancreatic cancer
Seldom do you sense you’re witnessing a historic moment in cancer care but this feels like ras targeting has arrived
#ASCO26
@pgodfreysmith@birchlse@davidchalmers42 I was just thinking about you this week in my new role and wondering what Peter would have to say about LLMs...I do you hope you do some writing on this at some point.
@peterottsjo I loved these papers. But I also have to say, the future house paper (which is well done) did highlight a target that is actually pretty well known for AMD....
Last week was my last week at @genentech. It was an amazing 5 years. And now...something new! I've joined Beneficial Deployments and the AI for Life Sciences team at @AnthropicAI. Looking forward to continuing science conversations in this new role.
Excited to share Decima, out now in @naturemethods! 🎉
Existing seq-to-function models predict bulk expression. Decima goes further: it predicts gene expression in specific cell types and disease states from DNA sequence alone — trained on 22M+ single cells.
Applications: cis-regulatory mechanisms, cell-type-resolved variant effect prediction, and designing context-specific regulatory DNA
@MichaelGalvezMD@SantaClaraUniv Often, I think the incentive structure is often to keep the number of graduates low to keep the "product" rare. There just needs to be a lot more medical schools (and PA schools, and skilled nursing schools....etc)
A new medical school, the first in a century, is coming to the Bay Area thanks to a gift from Nvidia billionaire Mark Stevens and his wife Mary. It's a partnership between Sutter Health and Santa Clara University - two miles down the road from Nvidia HQ:
https://t.co/KBjC0Ok8f4
@ScienceYael@keviv9 Stick with it. Not keeping this kind of balance was ultimately what burned me out of an otherwise pretty successful academic career (happy where I landed...but man...that was not a wise path)